medlitГигиена и санитарияHygiene and Sanitation0016-99002412-0650Federal Scientific Center of Hygiene named after F.F. Erisman10.47470/0016-9900-2021-100-2-172-177medlit-1263Research ArticleПРОФИЛАКТИЧЕСКАЯ ТОКСИКОЛОГИЯ И ГИГИЕНИЧЕСКОЕ НОРМИРОВАНИЕPREVENTIVE TOXICOLOGY AND HYGIENIC STANDARTIZATIONЭффекты влияния меди и цинка на живые организмы (обзор литературы)Effects of the influence of copper and zinc on living organisms (literature review)https://orcid.org/0000-0003-3403-6477КопачАлександра ЕвгеньевнаKopachAlexandra Ye.

Доцент кафедры общей гигиены и экологии Тернопольского национального медицинского университета им. И.Я. Горбачевского, 46000, Тернополь, Украина.

e-mail: kopachole@tdmu.edu.ua

MD, PhD., assoc. Prof. of the Department of General Hygiene and Ecology I. Horbachevsky Ternopil National Medical University, Ternopil, 46000, Ukraine.

e-mail: kopachole@tdmu.edu.ua

kopachole@tdmu.edu.uahttps://orcid.org/0000-0001-9860-4889ФедоривО. Е.FedorivOlha Ye.noemail@neicon.ruhttps://orcid.org/0000-0002-7357-7551МельникН. А.MelnykNataliia A.noemail@neicon.ruТНМУ Тернопольский национальный медицинский университет им. И.Я. Горбачевского МОЗ УкраиныHorbachevsky Ternopil National Medical University2021220320211002172177Copyright © Копач А.Е., Федорив О.Е., Мельник Н.А., 20212021Копач А.Е., Федорив О.Е., Мельник Н.А.Kopach A.Y., Fedoriv O.Y., Melnyk N.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.rjhas.ru/jour/article/view/1263Введение

Введение. Несмотря на то что биологическое значение ионов меди и цинка в организме основательно изучается в течение многих лет учёными разных стран, в том числе в государственных лабораториях, значение нехватки или избытка указанных металлов и их соединений в организме для здоровья в значительной степени остаётся недооцененным.

Цель работы – изучить патогенез травматической болезни, возникающей на фоне дисбаланса меди и цинка в организме.

В работе использованы библиосемантические и аналитические методы. Был проведён поиск литературы по следующим запросам: «цинк, медь, тяжёлые металлы, негативное влияние». Поиск проведён по базам данных PubMed, Scopus, Web of Science и Google Scholar для различных статей. Все публикации были проанализированы и включены в этот обзор.

Важность недостатка или избытка этих металлов и их соединений в организме остаётся в значительной степени недооценённой. Особенности патогенеза многих заболеваний, возникающих на фоне дисбаланса меди и цинка в организме, также не изучены. Травматическое заболевание не было исключением, так как это не учитывалось в экспериментальной и клинической медицине.

Заключение

Заключение. Из анализа доступной научной литературе не найдено сообщений об особенностях течения травматической болезни в условиях избыточного поступления ионов меди и цинка в организм. Можно только предположить, что нарушение функциональной способности печени, лёгких, мозга и других органов, которое возникает на фоне поражения ионами тяжёлых металлов, создаёт неблагоприятный фон для протекания тяжёлой травмы.

Introduction

Introduction. Scientists from Horbachevsky Ternopil National Medical University, Ternopil, and various countries, including state laboratories, have thoroughly studied the biological significance of copper and zinc ions in the body for many years. Nevertheless, the value of the shortage or excess of these metals and their compounds in the body remains mostly underestimated for health. 

Purpose of work

Purpose of work: to study the pathogenesis of traumatic disease occurring due to an imbalance of copper and zinc in the body.

Methods

Methods. Bibliosemantic and analytical methods were used. A literature search was conducted for the following queries as zinc, copper, heavy metals, negative impact. The investigation was performed with PubMed, Scopus, Web of Science, and Google Scholar for various articles. All publications have been analyzed and included in this review. The importance of these metals’ lack or excess and their compounds in the body remains mostly underestimated. Features of the pathogenesis of many diseases occurring due to imbalance of copper and zinc in the body have also been unexplored. The traumatic disorder was no exception, as this was not considered in experimental and clinical medicine.

Conclusion

Conclusion. From the analysis of the available scientific literature, no messages were found about the features of the course of traumatic disease in conditions of excessive intake of copper and zinc ions in the body. We can only assume that a violation of the functional ability of the liver, lungs, brain and other organs that occurs against the background of heavy metal ion damage creates an unfavorable background for the occurrence of a serious injury.

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The authors declare that there are no conflicts of interest present.