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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medlit</journal-id><journal-title-group><journal-title xml:lang="ru">Гигиена и санитария</journal-title><trans-title-group xml:lang="en"><trans-title>Hygiene and Sanitation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0016-9900</issn><issn pub-type="epub">2412-0650</issn><publisher><publisher-name>Federal Scientific Center of Hygiene named after F.F. Erisman</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47470/0016-9900-2021-100-6-594-597</article-id><article-id custom-type="elpub" pub-id-type="custom">medlit-1523</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МЕДИЦИНА ТРУДА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OCCUPATIONAL HEALTH</subject></subj-group></article-categories><title-group><article-title>Состояние и перспективы гигиенического нормирования производственной среды с пониженным содержанием кислорода (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>State and prospects of hygienic regulation of the production environment with a reduced oxygen content (literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8317-2718</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бухтияров</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bukhtiyarov</surname><given-names>Igor V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9973-3508</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шестопалов</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shestopalov</surname><given-names>Nikolay V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0991-6237</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Винников</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vinnikov</surname><given-names>Denis V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5704-0650</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Глухов</surname><given-names>Дмитрий Валерьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Glukhov</surname><given-names>Dmitry V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор мед. наук, доцент, вед. науч. сотр. лаб. физиологии труда и профилактической эргономики ФГБНУ «НИИ медицины труда имени академика Н.Ф. Измерова», 105275, Москва.</p><p>e-mail: d.gluhov@irioh.ru</p></bio><bio xml:lang="en"><p>Leading researcherof the laboratory of occupational physiology and preventive ergonomics, Academician Izmerov Research Institute of Medicine of Labor, Academician Izmerov, Moscow, 105275, Russian Federation.</p><p>e-mail: d.gluhov@irioh.ru</p></bio><email xlink:type="simple">d.gluhov@irioh.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6493-502X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Почтарева</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Pochtareva</surname><given-names>Elena S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3017-9251</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джергения</surname><given-names>С. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Dgergeniya</surname><given-names>Svetlana L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт медицины труда имени академика Н.Ф. Измерова»; ФГАОУ ВО «Первый московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский Университет)»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Academician Izmerov Research Institute of Medicine of Labor; Department of occupational medicine, aviation, space and diving medicine of the Sechenov First Moscow State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФБУН «Научно-исследовательский институт дезинфектологии» Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Disinfectology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Казахский национальный университет имени аль-Фараби</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Al-Farabi Kazakh National University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт медицины труда имени академика Н.Ф. Измерова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Academician Izmerov Research Institute of Medicine of Labor</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский Университет)»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Department of occupational medicine, aviation, space and diving medicine of the Sechenov First Moscow State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>14</day><month>07</month><year>2021</year></pub-date><volume>100</volume><issue>6</issue><fpage>594</fpage><lpage>597</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бухтияров И.В., Шестопалов Н.В., Винников Д.В., Глухов Д.В., Почтарева Е.С., Джергения С.Л., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Бухтияров И.В., Шестопалов Н.В., Винников Д.В., Глухов Д.В., Почтарева Е.С., Джергения С.Л.</copyright-holder><copyright-holder xml:lang="en">Bukhtiyarov I.V., Shestopalov N.V., Vinnikov D.V., Glukhov D.V., Pochtareva E.S., Dgergeniya S.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rjhas.ru/jour/article/view/1523">https://www.rjhas.ru/jour/article/view/1523</self-uri><abstract><p>Работа посвящена вопросам физиолого-гигиенических основ безопасности деятельности в изменённых условиях газовой среды, а также характеристикам основных медицинских мероприятий по обеспечению безопасности персонала при работе в условиях гипоксической газовой среды, анализу отечественных и зарубежных данных, изучению условий труда в среде обитания при пониженной концентрации кислорода в воздухе. Проводились исследования помещений с различными технологическими процессами, имеющими изменённую газовую среду, пониженную концентрацию кислорода при выполнении работниками различных операций, оценивалось состояние здоровья работников в зависимости от времени нахождения в изменённой газовой среде и процентного содержания кислорода. Проведён поиск литературы по базам данных Scopus, Web of Science, MedLine, The Cochrane Library, EMBASE, Global Health, CyberLeninka, РИНЦ. В результате проведённой работы сформулированы предложения по проекту санитарных правил и нормативов, которые необходимы для установления санитарно-эпидемиологических требований к среде обитания при пониженной концентрации кислорода в воздухе, а также к организации контроля, методам измерения компонентов воздушной среды на рабочих местах и мерам профилактики вредного воздействия на здоровье работающих, распространяющихся на условия труда в среде обитания для всех помещений при пониженной концентрации кислорода в воздухе.</p></abstract><trans-abstract xml:lang="en"><p>The work is devoted to the physiological and hygienic foundations of the safety of activities in the conditions of the changed gas environment and characteristics of the main medical measures for the employees’ protection in a hypoxic environment, the analysis of domestic and foreign data, the study of working conditions in the environment with the reduced oxygen concentration in the air. Investigations were carried out on premises with various technological processes, a changing environment, and a reduced oxygen concentration when employees perform multiple operations. The health status of workers was assessed depending on the time spent in the changed gas environment and the percentage of oxygen. Having analyzed the regulatory documents currently existing in the Russian Federation on the assessment and control of production factors, working conditions in confined spaces with a low oxygen concentration in the air, air environment to maintain health, high performance, and prevent diseases, experts concluded that it is necessary to develop Sanitary Rules and Norms, SanPiN “Sanitary and Epidemiological Requirements for Habitability (Stay) in Confined Spaces with a Low Oxygen Concentration in the Air” because currently there is no document existing specifically on this issue. The literature was searched in the databases Scopus, Web of Science, MedLine, The Cochrane Library, EMBASE, Global Health, CyberLeninka, RSCI. There were prepared draft sanitary plans and standards “Sanitary and epidemiological requirements for the environment with a reduced concentration of oxygen in the air,” which establish sanitary and epidemiological requirements for the environment with a reduced concentration of oxygen in the air, as well as for the organization of control, methods measurements of air components at workplaces and measures to prevent harmful effects on the health of workers. They apply to work conditions in the living environment for all premises with a reduced oxygen concentration in the air.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>изменённая газовая среда</kwd><kwd>пониженная концентрация кислорода</kwd><kwd>условия труда</kwd><kwd>гипоксия</kwd><kwd>компенсаторные механизмы</kwd><kwd>адаптационные процессы</kwd><kwd>обзор</kwd></kwd-group><kwd-group xml:lang="en"><kwd>modified gas environment</kwd><kwd>reduced oxygen concentration</kwd><kwd>working conditions</kwd><kwd>hypoxia</kwd><kwd>compensatory mechanisms</kwd><kwd>adaptation processes</kwd><kwd>review</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kimmerle G., Bayer-Aktiengesellschaft L. Aspects and methodology for the evaluation of toxicological parameters during fire exposure. J. Fire Flammabil. Combust. Toxicol. Suppl. 1974; (1).</mixed-citation><mixed-citation xml:lang="en">Kimmerle G., Bayer-Aktiengesellschaft L. Aspects and methodology for the evaluation of toxicological parameters during fire exposure. J. Fire Flammabil. Combust. Toxicol. Suppl. 1974; (1).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Final Report. Fuel Tank Inerting Harmonization Working Group. Aviation Rulemaking Advisory Committee (ARAC); 2001.</mixed-citation><mixed-citation xml:lang="en">Final Report. Fuel Tank Inerting Harmonization Working Group. Aviation Rulemaking Advisory Committee (ARAC); 2001.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">National Fire Protection Association (NFPA). DiNenno P.J., ed. SFPE Handbook of Fire Protection Engineering. Quincy; 2003.</mixed-citation><mixed-citation xml:lang="en">National Fire Protection Association (NFPA). DiNenno P.J., ed. SFPE Handbook of Fire Protection Engineering. Quincy; 2003.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Monitoring for Oxygen. T.R. Consulting Inc.; 2004. Available at: https://www.trconsultinggroup.com/safety/last.html</mixed-citation><mixed-citation xml:lang="en">Monitoring for Oxygen. T.R. Consulting Inc.; 2004. Available at: https://www.trconsultinggroup.com/safety/last.html</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Occupational Safety &amp; Health Administration (OSHA); 2004. Available at: https://www.osha.gov/SLTC/smallbusiness/sec12.html</mixed-citation><mixed-citation xml:lang="en">Occupational Safety &amp; Health Administration (OSHA); 2004. Available at: https://www.osha.gov/SLTC/smallbusiness/sec12.html</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Разинкин С.М., Дворников М.В. Физиология и гигиена лётчика в экстремальных условиях. Монография. М.: Научная книга; 2017</mixed-citation><mixed-citation xml:lang="en">Razinkin S.M., Dvornikov M.V. Physiology and Hygiene of the Pilot in Extreme Conditions. Monograph [Fiziologiya i gigiena letchika v ekstremal’nykh usloviyakh]. Moscow: Nauchnaya kniga; 2017. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Chapman R.F., Stray-Gundersen J., Levine B.D. Individual variation in response to altitude training. J. Appl. Physiol. 1985; 85(4): 1448-56. https://doi.org/10.1152/jappl.1998.85.4.1448</mixed-citation><mixed-citation xml:lang="en">Chapman R.F., Stray-Gundersen J., Levine B.D. Individual variation in response to altitude training. J. Appl. Physiol. 1985; 85(4): 1448–56. https://doi.org/10.1152/jappl.1998.85.4.1448</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Безкишкий Э.Н., Иванов А.О., Петров В.А., Ерошенко А.Ю., Грошилин В.С., Анистратенко Л.Г. и соавт. Работоспособность человека при периодическом пребывании в гипоксических воздушных средах, снижающих пожароопасность гермообъектов. Экология человека. 2018; (9): 4-11. https://doi.org/10.33396/1728-0869-2018-9-4-11</mixed-citation><mixed-citation xml:lang="en">Bezkishkiy E.N., Ivanov A.O., Petrov V.A., Eroshenko A.Yu., Groshilin V.S., Anistratenko L.G., et al. Human working capacity in periodic stay in hypoxic air environments, reducing the fire hazard of sealed objects. Ekologiya cheloveka. 2018; (9): 4–11. https://doi.org/10.33396/1728-0869-2018-9-4-11 (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Davis C., Hackett P. Advances in the prevention and treatment of high altitude illness. Emerg. Med. Clin. 2017; 35(2): 241-60. https://doi.org/10.1016/j.emc.2017.01.002</mixed-citation><mixed-citation xml:lang="en">Davis C., Hackett P. Advances in the prevention and treatment of high altitude illness. Emerg. Med. Clin. 2017; 35(2): 241–60. https://doi.org/10.1016/j.emc.2017.01.002</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Vinnikov D., Brimkulov N., Redding-Jones R. Four-year prospective study of lung function in workers in a high altitude (4000 m) mine. High Alt. Med. Biol. 2011; 12(1): 65-9. https://doi.org/10.1089/ham.2010.1033</mixed-citation><mixed-citation xml:lang="en">Vinnikov D., Brimkulov N., Redding-Jones R. Four-year prospective study of lung function in workers in a high altitude (4000 m) mine. High Alt. Med. Biol. 2011; 12(1): 65–9. https://doi.org/10.1089/ham.2010.1033</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Vinnikov D. Drillers and mill operators in an open-pit gold mine are at risk for impaired lung function. J. Occup. Med. Toxicol. 2016; (11): 27. https://doi.org/10.1186/s12995-016-0114-9</mixed-citation><mixed-citation xml:lang="en">Vinnikov D. Drillers and mill operators in an open-pit gold mine are at risk for impaired lung function. J. Occup. Med. Toxicol. 2016; (11): 27. https://doi.org/10.1186/s12995-016-0114-9</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Krejcí J., Botek M., McKune A. Dynamics of the heart rate variability and oxygen saturation response to acute normobaric hypoxia within the first 10 min of exposure. Clin. Physiol. Funct. Imaging. 2018; 38(1): 56-62. https://doi.org/10.1111/cpf.12381</mixed-citation><mixed-citation xml:lang="en">Krejcí J., Botek M., McKune A. Dynamics of the heart rate variability and oxygen saturation response to acute normobaric hypoxia within the first 10 min of exposure. Clin. Physiol. Funct. Imaging. 2018; 38(1): 56–62. https://doi.org/10.1111/cpf.12381</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Vinnikov D., Brimkulov N., Krasotski V., Redding-Jones R., Blanc P.D. Risk factors for occupational acute mountain sickness. Occup. Med. (Lond.). 2014; 64(7): 483-9. https://doi.org/10.1093/occmed/kqu094</mixed-citation><mixed-citation xml:lang="en">Vinnikov D., Brimkulov N., Krasotski V., Redding-Jones R., Blanc P.D. Risk factors for occupational acute mountain sickness. Occup. Med. (Lond.). 2014; 64(7): 483–9. https://doi.org/10.1093/occmed/kqu094</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
