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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medlit</journal-id><journal-title-group><journal-title xml:lang="ru">Гигиена и санитария</journal-title><trans-title-group xml:lang="en"><trans-title>Hygiene and Sanitation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0016-9900</issn><issn pub-type="epub">2412-0650</issn><publisher><publisher-name>Federal Scientific Center of Hygiene named after F.F. Erisman</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47470/0016-9900-2021-100-11-1236-1243</article-id><article-id custom-type="elpub" pub-id-type="custom">medlit-1840</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МЕДИЦИНА ТРУДА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OCCUPATIONAL HEALTH</subject></subj-group></article-categories><title-group><article-title>Психическое здоровье, связанное с трудом: современное состояние проблемы (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Work-related mental health: current state of the art (literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8317-2718</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бухтияров</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bukhtiyarov</surname><given-names>Igor V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2771-1617</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Денисов</surname><given-names>Э. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Denisov</surname><given-names>Eduard I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7078-7238</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жовнерчук</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhovnerchuk</surname><given-names>Evgeny V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7523-4686</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сериков</surname><given-names>Василий Васильевич</given-names></name><name name-style="western" xml:lang="en"><surname>Serikov</surname><given-names>Vasiliy V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Канд. психол. наук, зав. лаб. физиологии и профилактической эргономики ФГБНУ «Научно-исследовательский институт медицины труда им. академика Н.Ф. Измерова», 105275, Москва.</p><p>e-mail: vasiliy_serikov@mail.ru</p></bio><email xlink:type="simple">vasiliy_serikov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2491-0204</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хатин</surname><given-names>Д. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Khatin</surname><given-names>Dmitry E.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4674-1886</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Московенко</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Moskovenko</surname><given-names>Alexey V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт медицины труда имени академика Н.Ф. Измерова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Izmerov Research Institute of Occupational Health</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт медицины труда имени академика Н.Ф. Измерова»; Академия постдипломного образования ФГБУ «Федеральный научно-клинический центр специализированных видов медицинской помощи и медицинских технологий Федерального медико-биологического агентства»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Izmerov Research Institute of Occupational Health; Academy of Postgraduate Education of the Federal Medical Biological Agency</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>06</day><month>12</month><year>2021</year></pub-date><volume>100</volume><issue>11</issue><fpage>1236</fpage><lpage>1243</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бухтияров И.В., Денисов Э.И., Жовнерчук Е.В., Сериков В.В., Хатин Д.Е., Московенко А.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Бухтияров И.В., Денисов Э.И., Жовнерчук Е.В., Сериков В.В., Хатин Д.Е., Московенко А.В.</copyright-holder><copyright-holder xml:lang="en">Bukhtiyarov I.V., Denisov E.I., Zhovnerchuk E.V., Serikov V.V., Khatin D.E., Moskovenko A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rjhas.ru/jour/article/view/1840">https://www.rjhas.ru/jour/article/view/1840</self-uri><abstract><sec><title>Введение</title><p>Введение. Психическое здоровье – неотъемлемая часть здоровья, а его нарушения чреваты социально-экономическими издержками для личности и общества. По данным Всемирной организации здравоохранения (ВОЗ), наиболее распространённым заболеванием и основной причиной инвалидности в мире является депрессия; от неё страдают 350 млн человек. Актуален анализ новых данных и концепций по этим вопросам.</p><p>Цель работы – изучение проблемы стресса на работе и нарушений психического здоровья с анализом концепции аллостаза и аллостатической нагрузки как интегрального показателя стресса.</p><p>Поиск литературы проводили до сентября 2020 года с использованием баз данных научной литературы Scopus (https://www.scopus.com/home.uri) и MedLine/PubMed (https://www.ncbi.nlm.nih.gov/PubMed). Ключевые термины поиска включали «mental health problems», «mental health in the workplace», «working condition», «anxiety», «burnout», «depression». Рассматривали полнотекстовые статьи, опубликованные на английском языке в журналах с присвоенными цифровыми идентификаторами объектов (DOI, англ. digital object identifier). </p><p>Рассмотрены связанные с работой факторы, вызывающие стресс, – их также называют психосоциальными рисками. Приведены данные по видам и размерам медико-социального ущерба от нарушений психического здоровья в странах Европы и США, а также детально рассмотрен опыт Италии по ограничению стресса, связанного с работой. Даны примеры законодательства по ограничению психосоциальных рисков на работе в странах Европы, а также схемы признания связи психических расстройств с работой. Проанализирован сдвиг медико-биологической парадигмы – от гомеостаза к аллостазу  – и описаны аллостаз и аллостатическая нагрузка как интегральный показатель хронического стресса на работе. Несмотря на изобилие работ по стрессу и депрессии, в литературе нет единства в понимании механизмов и этапов формирования нарушений психического здоровья от стрессов на работе. Не ясно, что лучше отражает эффект хронического стресса, связанного с работой: аллостатическая нагрузка или метаболический синдром. Стресс, депрессия и выгорание – каково соотношение между ними? Можно говорить о логической цепочке: профессиональный фактор риска – утомление – стресс – депрессия – выгорание – нарушение здоровья и профессиональная деформация. Изложены вопросы появления Международной классификации болезней 11-го пересмотра (МКБ-11), ожидаемого в 2021 году, и, в частности, синдром выгорания. Рассмотрены возможности информационных технологий и Интернета в профилактике и лечении нарушений психического здоровья.</p></sec><sec><title>Заключение</title><p>Заключение. Отмечается всё возрастающая роль проблемы стресса в жизни современного общества. Необходима разработка методов ограничения психосоциальных факторов риска и критериев ранней диагностики нарушений психического здоровья работников. Перспективны программы сохранения и укрепления психического здоровья (e-MentalHealth – электронное психическое здоровье), основанные на онлайн-консультациях с помощью Интернета.</p></sec><sec><title>Участие авторов</title><p>Участие авторов: Бухтияров И.В. — утверждение окончательного варианта статьи;Денисов Э.И. — концепция и дизайн исследования, сбор и обработка данных литературы, материала, написание текста; Жовнерчук Е.В. — написание текста, редактирование, ответственность за целостность всех частей статьи;Сериков В.В. — написание текста, редактирование;Хатин Д.Е. — написание текста, редактирование, сбор данных литературы;Московенко А.В. — редактирование. </p></sec><sec><title>Конфликт интересов</title><p>Конфликт интересов. Авторы декларируют отсутствие явных и потенциальных конфликтов интересов в связи с публикацией данной статьи.</p></sec><sec><title>Финансирование</title><p>Финансирование. Исследование не имело спонсорской поддержки.</p></sec><sec><title>Поступила</title><p>Поступила: 13.05.2020 / Принята к печати: 28.09.2021 / Опубликована: 30.11.2021</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Mental health is an integral part of health, and its disorders are fraught with social and economic costs for the individual and society. According to WHO, depression is the most common disease and the leading cause of disability globally; it affects 350 million people. The analysis of new data and concepts on these issues is relevant. </p><p>The aim of the work is to study the problem of stress at work and mental health disorders with an analysis of the concept of allostasis and allostatic load as an integral indicator of stress.</p><p>A literature search was conducted through September 2020 using the Scopus (https://www.scopus.com/home.uri) and MedLine/PubMed (https://www.ncbi.nlm.nih.gov/PubMed) scientific literature databases. Key search terms included “mental health problems,” “mental health in the workplace,” “working condition,” “anxiety,” “burnout,” and “depression. Full-text articles published in English in journals with DOIs were reviewed.</p><p>There are considered work-related stressors, also called psychosocial risks. Data on the types and amounts of medico-social damage from mental health disorders in European countries and the United States are presented. The Italian experience in limiting work-related stress is reviewed in detail. There are given examples of legislation to restrict psychosocial risks at work in European countries, as well as patterns of recognition of the connection between mental disorders and work. The biomedical paradigm shift — from homeostasis to allostasis — is analyzed, and allostasis and allostatic load is described as integral indicator of chronic work stress. Despite an abundance of work on anxiety and depression, there is no unity in the literature in understanding the mechanisms and stages of mental health disorders from stress at work. It is not clear what better reflects the effects of chronic work-related stress: allostatic stress or metabolic syndrome. Stress, depression and burnout — what is the relation between them? We can discuss a logical chain: occupational risk factors — fatigue, stress — depression, burnout, health disorder, and occupational deformity. The questions of ICD-11, expected to appear in 2021, and, in particular, burnout syndrome, are outlined. The possibilities of information technologies and the Internet in preventing and treating mental health disorders are considered.</p></sec><sec><title>Conclusions</title><p>Conclusions. The increasing role of stress problems in the life of modern society is noted. The methods of psychosocial risk factors limitation and mental health disorders diagnostics need to be developed. Internet-based programs for the preservation and promotion of mental health (e-MentalHealth) are promising.</p></sec><sec><title>Contribution</title><p>Contribution: Bukhtiyarov I.V. — editing the text;Denisov E.I. — concept, research design, literature data collection, text writing, material collection and data processing; Zhovnerchuk E.V. — text writing, editing, responsibility for the integrity of all parts of the article; Serikov V.V. – text writing, editing;Khatin D.E. — text writing, editing, collection of literature data;Moskovenko A.V. — editing.All authors are responsible for the integrity of all parts of the manuscript and approval of the manuscript final version.</p></sec><sec><title>Conflict of interest</title><p>Conflict of interest. The authors declare no conflict of interest.</p></sec><sec><title>Acknowledgement</title><p>Acknowledgement. The study had no sponsorship.</p></sec><sec><title>Received</title><p>Received: May 13, 2021 / Accepted: September 28, 2021 / Published: November 30, 2021</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>условия труда</kwd><kwd>психическое здоровье</kwd><kwd>стресс</kwd><kwd>тревога</kwd><kwd>депрессия</kwd><kwd>синдром выгорания</kwd><kwd>МКБ-11</kwd><kwd>профилактика</kwd><kwd>киберфизическая система</kwd><kwd>обзор</kwd></kwd-group><kwd-group xml:lang="en"><kwd>working conditions</kwd><kwd>mental health</kwd><kwd>stress</kwd><kwd>anxiety</kwd><kwd>depression</kwd><kwd>burnout syndrome</kwd><kwd>ICD-11</kwd><kwd>prevention</kwd><kwd>cyberphysical system</kwd><kwd>review</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">WHO. Basic documents, 47th ed. Geneva; 2009.</mixed-citation><mixed-citation xml:lang="en">WHO. Basic documents, 47th ed. Geneva; 2009.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">WHO. Strengthening mental health promotion. Fact sheet, No. 220. Geneva, World Health Organization, 2018. https://www.who.int/news-room/fact-sheets/detail/mental-health-strengthening-our-response</mixed-citation><mixed-citation xml:lang="en">WHO. Strengthening mental health promotion. Fact sheet, No. 220. Geneva, World Health Organization, 2018. https://www.who.int/news-room/fact-sheets/detail/mental-health-strengthening-our-response</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Khaitan S.K., McCalley J.D. Design techniques and applications of cyber physical systems: a survey. IEEE Systems Journal. 2015; 9(2): 350-65.</mixed-citation><mixed-citation xml:lang="en">Khaitan S.K., McCalley J.D. Design techniques and applications of cyber physical systems: a survey. IEEE Systems Journal. 2015; 9(2): 350–65.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Hanis T., Smith A., Senegal J., Greenlee K. Building a smarter medical device monitoring solution. Smarter Planet solutions with sensor monitoring. Part 3. DeveloperWorks archives; 2010: 1-19.</mixed-citation><mixed-citation xml:lang="en">Hanis T., Smith A., Senegal J., Greenlee K. Building a smarter medical device monitoring solution. Smarter Planet solutions with sensor monitoring. Part 3. DeveloperWorks archives; 2010: 1–19.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Banerjee A., Gupta S.K.S., Fainekos G., Varsamopoulos G. Towards modeling and analysis of cyber-physical medical systems. In: Proceedings of the 4th International Symposium on Applied Sciences in Biomedical and Communication Technologies (ISABEL 11). New York; 2011: 154. https://doi.org/10.1145/2093698.2093852</mixed-citation><mixed-citation xml:lang="en">Banerjee A., Gupta S.K.S., Fainekos G., Varsamopoulos G. Towards modeling and analysis of cyber-physical medical systems. In: Proceedings of the 4th International Symposium on Applied Sciences in Biomedical and Communication Technologies (ISABEL 11). New York; 2011: 154. https://doi.org/10.1145/2093698.2093852</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Lee E.A. The Past, present and future of cyber-physical systems: A focus on models. Sensors (Basel). 2015; 15(3): 4837-69. https://doi.org/10.3390/s150304837</mixed-citation><mixed-citation xml:lang="en">Lee E.A. The Past, present and future of cyber-physical systems: A focus on models. Sensors (Basel). 2015; 15(3): 4837–69. https://doi.org/10.3390/s150304837</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Зегжда Д.П., Павленко Е.Ю. Оценка и обеспечение устойчивости управления киберфизическими системами в условиях компьютерных атак. В кн.: XIII Всероссийское совещание по проблемам управления ВСПУ-2019. М.; 2019: 2545-9</mixed-citation><mixed-citation xml:lang="en">Zegzhda D.P., Pavlenko E.Yu. Estimation and maintenance of stability of management of cyberphysical systems in the conditions of computer attacks. In: XIII All-Russian Meeting on Management Problems [XIII Vserossiyskoe soveshchanie po problemam upravleniya VSPU-2019]. Moscow; 2019: 2545–9. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Seiger R., Huber S., Heisig P., Assmann U. Enabling self-adaptive workflows for cyber-physical systems. In: Lecture Notes in Business Information Processing. 2016; 248: 3-17.</mixed-citation><mixed-citation xml:lang="en">Seiger R., Huber S., Heisig P., Assmann U. Enabling self-adaptive workflows for cyber-physical systems. In: Lecture Notes in Business Information Processing. 2016; 248: 3–17.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Zegzhda D.P., Pavlenko E.Yu. Cyber-physical system homeostatic security management. Aut. Control Comp. Sci. 2017; 51: 805-16. https://doi.org/10.3103/S0146411617080260</mixed-citation><mixed-citation xml:lang="en">Zegzhda D.P., Pavlenko E.Yu. Cyber-physical system homeostatic security management. Aut. Control Comp. Sci. 2017; 51: 805–16. https://doi.org/10.3103/S0146411617080260</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Yu V.L., Fagan L.M., Wraith S.M., Clancey W.J., Scott A.C., Hannigan J., et al. Antimicrobial selection by a computer. A blinded evaluation by infectious diseases experts. JAMA. 1979; 242(2): 1279-82. https://doi.org/10.1001/jama.1979.03300120033020</mixed-citation><mixed-citation xml:lang="en">Yu V.L., Fagan L.M., Wraith S.M., Clancey W.J., Scott A.C., Hannigan J., et al. Antimicrobial selection by a computer. A blinded evaluation by infectious diseases experts. JAMA. 1979; 242(2): 1279–82. https://doi.org/10.1001/jama.1979.03300120033020</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Стародубцев А.А. Система поддержки принятия решений. Актуальные проблемы авиации и космонавтики. 2016; 2(12): 99-101.</mixed-citation><mixed-citation xml:lang="en">Starodubtsev A.A. Decision support system. Aktual’nye problemy aviatsii i kosmonavtiki. 2016; 2(12): 99–101. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Колесникова А.С., Федонников А.С., Кириллова И.В., Ульянов В.Ю., Левченко К.К., Киреев С.И. и соавт. Возможности систем поддержки принятия решений в контексте хирургии позвоночно-тазового комплекса (аналитический обзор). Гений ортопедии. 2019; 25(2): 243-53. https://doi.org/10.18019/1028-4427-2019-25-2-243-253</mixed-citation><mixed-citation xml:lang="en">Kolesnikova A.S., Fedonnikov A.S., Kirillova I.V., Ulyanov V.Yu., Levchenko K.K., Kireev S.I., et al. The possibilities with decision support systems in surgery of spine-pelvic complex (analytical review). Geniy ortopedii. 2019; 25(2): 243–53. https://doi.org/10.18019/1028-4427-2019-25-2-243-253 (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Greenes R.A., ed. Clinical Decision Support: The Road Ahead. Elsevier; 2007</mixed-citation><mixed-citation xml:lang="en">Greenes R.A., ed. Clinical Decision Support: The Road Ahead. Elsevier; 2007.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Зарипова Г.Р., Богданова Ю.А., Катаев В.А., Ханов В.О. Современные модели экспертных систем поддержки принятия врачебных решений в прогнозировании операционного риска в хирургической практике. Таврический медико-биологический вестник. 2016; 19(4): 140-5</mixed-citation><mixed-citation xml:lang="en">Zaripova G.R., Bogdanova Yu.A., Kataev V.A., Khanov V.O. Modern models of the expert systems making support medical decisions in prediction of operational risk in surgical practice. Tavricheskiy mediko-biologicheskiy vestnik. 2016; 19(4): 140–5. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Roslyakov A.V., ed. Internet of Things [Internet veshchey]. Samara: As Gard; 2014. (in Russian)</mixed-citation><mixed-citation xml:lang="en">Roslyakov A.V., ed. Internet of Things [Internet veshchey]. Samara: As Gard; 2014. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">McEwen A., Cassimally H. Designing the Internet of Things. Wiley &amp; Sons; 2014.</mixed-citation><mixed-citation xml:lang="en">McEwen A., Cassimally H. Designing the Internet of Things. Wiley &amp; Sons; 2014.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Trends Emerge in the Gartner Hype Cycle for Emerging Technologies. Smarter With Gartner; 2018. Available at: https://www.gartner.com/smarterwithgartner/5-trends-emerge-in-gartner-hype-cycle-for-emerging-technologies-2018/</mixed-citation><mixed-citation xml:lang="en">Trends Emerge in the Gartner Hype Cycle for Emerging Technologies. Smarter With Gartner; 2018. Available at: https://www.gartner.com/smarterwithgartner/5-trends-emerge-in-gartner-hype-cycle-for-emerging-technologies-2018/</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Manyika J., Chui M., Bisson P., Woetzel J., Dobbs R., Bughin J., et al. The Internet of Things: Mapping the Value Beyond the Hype. McKinsey Global Institute; 2015. Available at: https://www.mckinsey.com/~/media/McKinsey/Industries/Technology%20Media%20and%20Telecommunications/High%20Tech/Our%20Insights/The%20Internet%20of%20Things%20The%20value%20of%20digitizing%20the%20physical%20world/Unlocking_the_potential_of_the_Internet_of_Things_Executive_summary.ashx</mixed-citation><mixed-citation xml:lang="en">Manyika J., Chui M., Bisson P., Woetzel J., Dobbs R., Bughin J., et al. The Internet of Things: Mapping the Value Beyond the Hype. McKinsey Global Institute; 2015. Available at: https://www.mckinsey.com/~/media/McKinsey/Industries/Technology%20Media%20and%20Telecommunications/High%20Tech/Our%20Insights/The%20Internet%20of%20Things%20The%20value%20of%20digitizing%20the%20physical%20world/Unlocking_the_potential_of_the_Internet_of_Things_Executive_summary.ashx</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Росляков А.В., ред. Интернет вещей. Самара: Ас Гард; 2014.</mixed-citation><mixed-citation xml:lang="en">Six major trends in digital medicine 2019. First Line Software; 2019. https://firstlinesoftware.ru/news/6-glavnyhtrendov-cifrovoj-mediciny-2019/ (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Шесть главных трендов цифровой медицины 2019. First Line Software; 2019. Доступно: https://firstlinesoftware.ru/news/6-glavnyh-trendov-cifrovoj-mediciny-2019/</mixed-citation><mixed-citation xml:lang="en">Kupriyanovskiy V.P., Namnot E.D., Sinyagov S.A. Cyber-physical systems as a base of digital economy. Int. J. Open Inf. Technol. 2016; 4(2): 18–25. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Куприяновский В.П., Намнот Е.Д., Синягов С.А. Кибер-физические системы как основа цифровой экономики. Int. J. Open Inf. Technol. 2016; 4(2): 18-25.</mixed-citation><mixed-citation xml:lang="en">Government of the Russian Federation. Digital economy of the Russian Federation. 2017. Available at: https://www.tadviser.ru/images/a/af/9gFM4FHj4PsB79I5v7yLVuPgu4bvR7M0.pdf (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Правительство Российской Федерации. Цифровая экономика Российской Федерации; 2017. Доступно: https://www.tadviser.ru/images/a/af/9gFM4FHj4PsB79I5v7yLVuPgu4bvR7M0.pdf</mixed-citation><mixed-citation xml:lang="en">Selye H. Stress Without Distress. Philadelphia-New York; 1974.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Селье Г. Стресс без дистресса. Пер. с англ. М.: ПРОГРЕСС; 1982.</mixed-citation><mixed-citation xml:lang="en">Sudakov K.V. Emotional stress. In: Petrovskiy B.V., ed. Great Medical Encyclopedia. Volume 28 [Bol’shaya meditsinskaya entsiklopediya. Tom 28]. Available at: https://bme.org/index.php/EMOTsIONAL’’NYY_STRESS (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Судаков К.В. Эмоциональный стресс. В кн.: Петровский Б.В., ред. Большая медицинская энциклопедия. Том 28. Доступно: https://бмэ.орг/index.php/ЭМОЦИОНАЛЬНЫЙ_СТРЕСС</mixed-citation><mixed-citation xml:lang="en">Denisov E.I., Pfaf V.F., Stepanyan I.V., Gorokhova S.G. The shift of medical and biological paradigm: From homeostasis to allostasis. Neyrokomp’yutery: razrabotka i primenenie. 2016; (2): 16–21. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Денисов Э.И., Пфаф В.Ф., Степанян И.В., Горохова С.Г. Сдвиг медико-биологической парадигмы: от гомеостаза к аллостазу. Нейрокомпьютеры: разработка и применение. 2016; (2): 16-21.</mixed-citation><mixed-citation xml:lang="en">Workplace stress: A collective challenge. World Day for Safety and Health at Work 28 April 2016. Geneva: ILO; 2016.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Стресс на рабочем месте: коллективный вызов. Всемирный день охраны труда 28 апреля 2016 г. Женева: МОТ; 2016.</mixed-citation><mixed-citation xml:lang="en">Ramazzini B. De morbis artificum diatriba. Ultrajecti: Guilielmum van de Water; 1709.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Cimaglia G., Goggiamani A., Orsini D. Medical-legal criteriology for the recognition and compensation of stress-related diseases INAIL protection. In: Conference of the European Forum. Copenhagen; 2008.</mixed-citation><mixed-citation xml:lang="en">Cimaglia G., Goggiamani A., Orsini D. Medical-legal criteriology for the recognition and compensation of stress-related diseases INAIL protection. In: Conference of the European Forum. Copenhagen; 2008.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Aiello A., Tesi A. Gestire lo stress da lavorocorrelato. In: Giannini M., Bellandi G., eds. La gestione integrata delle risorse umane nelle organizzazioni. Pisa University Press; 2016. Available at: https://www.researchgate.net/publication/305764222_Gestire_lo_stress_da_lavoro_correlato</mixed-citation><mixed-citation xml:lang="en">Aiello A., Tesi A. Gestire lo stress da lavorocorrelato. In: Giannini M., Bellandi G., eds. La gestione integrata delle risorse umane nelle organizzazioni. Pisa University Press; 2016. Available at: https://www.researchgate.net/publication/305764222_Gestire_lo_stress_da_lavoro_correlato</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Hewlett E., Moran V. Making mental health count: The social and economic costs of neglecting mental health care. OECD Health Policy Studies. 2014; 246. https://doi.org/10.1787/9789264208445-en</mixed-citation><mixed-citation xml:lang="en">Hewlett E., Moran V. Making mental health count: The social and economic costs of neglecting mental health care. OECD Health Policy Studies. 2014; 246. https://doi.org/10.1787/9789264208445-en</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Recommendation of the Council on integrated mental health, skills and work policy. Series: OECD legal instruments OECD/LEGAL/0420; 2020. Available at: https://legalinstruments.oecd.org/en/instruments/334</mixed-citation><mixed-citation xml:lang="en">Recommendation of the Council on integrated mental health, skills and work policy. Series: OECD legal instruments OECD/LEGAL/0420; 2020. Available at: https://legalinstruments.oecd.org/en/instruments/334</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Andlin-Sobocki P., Jonsson B., Wittchen H.U., Olesen J. Cost of disorders of the brain in Europe. Eur. J. Neurol. 2005; 12 (Suppl. 1): 1-27.</mixed-citation><mixed-citation xml:lang="en">Andlin-Sobocki P., Jonsson B., Wittchen H.U., Olesen J. Cost of disorders of the brain in Europe. Eur. J. Neurol. 2005; 12 (Suppl. 1): 1–27.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Leal J., Luengo-Fernández R., Gray A., Petersen S., Rayner M. Economic burden of cardiovascular diseases in the enlarged European Union. Eur. Heart J. 2006; 27(13): 1610-9. https://doi.org/10.1093/eurheartj/ehi733</mixed-citation><mixed-citation xml:lang="en">Leal J., Luengo-Fernández R., Gray A., Petersen S., Rayner M. Economic burden of cardiovascular diseases in the enlarged European Union. Eur. Heart J. 2006; 27(13): 1610–9. https://doi.org/10.1093/eurheartj/ehi733</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">EUROGIP. Risquespsychosociaux au travail: uneproblématiqueeuropéenne. EUROGIP-47/F; 2010.</mixed-citation><mixed-citation xml:lang="en">EUROGIP. Risquespsychosociaux au travail: uneproblématiqueeuropéenne. EUROGIP-47/F; 2010.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Fransson E.I., Nyberg S.T., Heikkilä K., Alfredsson L., Bjorner J.B., Borritz M., et al. Job strain and the risk of stroke: An individual-participant data meta-analysis. Stroke. 2015; 46(2): 557-9. https://doi.org/10.1161/STROKEAHA.114.008019</mixed-citation><mixed-citation xml:lang="en">Fransson E.I., Nyberg S.T., Heikkilä K., Alfredsson L., Bjorner J.B., Borritz M., et al. Job strain and the risk of stroke: An individual-participant data meta-analysis. Stroke. 2015; 46(2): 557–9. https://doi.org/10.1161/STROKEAHA.114.008019</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Рамаццини Б. О болезнях ремесленников: Рассуждения Demorbisartificum. Diatriba. Пер. с лат. М.: Медгиз; 1961</mixed-citation><mixed-citation xml:lang="en">Kazakovtsev B.A., Demcheva N.K., Kakorina E.P. Injuries, poisonings and other external influences as predictors of mental health indicators in Russia. Psikhicheskoe zdorov’e. 2017; 15(3): 9–15. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">National Institute of Mental Health. Mental illness website. Available at: https://www.nimh.nih.gov/index.shtml</mixed-citation><mixed-citation xml:lang="en">National Institute of Mental Health. Mental illness website. Available at: https://www.nimh.nih.gov/index.shtml</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Stewart W.F., Ricci J.A., Chee E., Hahn S.R., Morganstein D. Cost of lost productive work time among US workers with depression. JAMA. 2003; 289(23): 3135-44. https://doi.org/10.1001/jama.289.23.3135</mixed-citation><mixed-citation xml:lang="en">Stewart W.F., Ricci J.A., Chee E., Hahn S.R., Morganstein D. Cost of lost productive work time among US workers with depression. JAMA. 2003; 289(23): 3135–44. https://doi.org/10.1001/jama.289.23.3135</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Leigh J.P., Cone J.E., Harrison R. Costs of occupational injuries and illnesses in California. Prev. Med. 2001; 32(5): 393-406. https://doi.org/10.1006/pmed.2001.0841</mixed-citation><mixed-citation xml:lang="en">Leigh J.P., Cone J.E., Harrison R. Costs of occupational injuries and illnesses in California. Prev. Med. 2001; 32(5): 393–406. https://doi.org/10.1006/pmed.2001.0841</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Казаковцев Б.А., Демчева Н.К., Какорина Е.П. Травмы, отравления и другие внешние воздействия как предикторы показателей психического здоровья в России. Психическое здоровье. 2017; 15(3): 9-15</mixed-citation><mixed-citation xml:lang="en">Merikangas K.R., Ames M., Cui L., Ustun T.B., Von Korff M., Kessler R.C. The impact of comorbidity of mental and physical conditions on role disability in the US adult household population. Arch. Gen. Psychiatry. 2007; 64(10): 1180–8. https://doi.org/10.1001/archpsyc.64.10.1180</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Pavlov I.P. Nobel speech. In: «Nobel Lectures - 100 years: Physiology and Medicine». Volume 1 (1901-1909) [«Nobelevskie lektsii - 100 let: Fiziologiya i meditsina». Tom 1 (1901-1909)]. Moscow: GEOTAR-Media; 2006. (in Russian)</mixed-citation><mixed-citation xml:lang="en">Pavlov I.P. Nobel speech. In: «Nobel Lectures - 100 years: Physiology and Medicine». Volume 1 (1901-1909) [«Nobelevskie lektsii – 100 let: Fiziologiya i meditsina». Tom 1 (1901-1909)]. Moscow: GEOTAR-Media; 2006. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Павлов И.П. Нобелевская речь. В кн.: «Нобелевские лекции - 100 лет: Физиология и медицина». Том 1 (1901-1909). М.: ГЭОТАР-Медиа; 2006.</mixed-citation><mixed-citation xml:lang="en">Bukhtiyarov I.V., Rubtsov M.Yu., Chesalin P.V. Clerkship’s occupational stress evaluation reliability. Ekologiya cheloveka. 2012; (11): 20–6. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Бухтияров И.В., Рубцов М.Ю., Чесалин П.В. Валидизация оценки профессионального стресса у работников офисов. Экология человека. 2012; (11): 20-6.</mixed-citation><mixed-citation xml:lang="en">Ustyantsev S.L. Entropy management in the body to reduce work severity and intensity. Meditsina truda i ekologiya cheloveka. 2015; (3): 216–20. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Устьянцев С.Л. Управление энтропией в организме для снижения тяжести и напряженности труда. Медицина труда и экология человека. 2015; (3): 216-20.</mixed-citation><mixed-citation xml:lang="en">Scott K.M., Lim C., Al-Hamzawi A., Alonso J., Bruffaerts R., Caldas-de-Almeida J.M., et al. Association of mental disorders with subsequent chronic physical conditions: work mental health surveys from 17 countries. JAMA Psychiatry. 2016; 73(2): 150–8. https://doi.org/10.1001/jamapsychiatry.2015.2688</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Lerner D., Henke R.M. What does research tell us about depression, job performance, and work productivity? J. Occup. Environ. Med. 2008; 50(4): 401-10. https://doi.org/10.1097/jom.0b013e31816bae50</mixed-citation><mixed-citation xml:lang="en">Lerner D., Henke R.M. What does research tell us about depression, job performance, and work productivity? J. Occup. Environ. Med. 2008; 50(4): 401–10. https://doi.org/10.1097/jom.0b013e31816bae50</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Cynthia D., Nordal K.C., Ballard D.W., Bufka L.F., Diaz-Granados J. Stress in America: Coping with Change, Part 1. Washington: American Psychological Association; 2017.</mixed-citation><mixed-citation xml:lang="en">Cynthia D., Nordal K.C., Ballard D.W., Bufka L.F., Diaz-Granados J. Stress in America: Coping with Change, Part 1. Washington: American Psychological Association; 2017.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Diagnostic and statistical manual of mental disorders. 5th ed. American Psychiatric Association; 2013. https://doi.org/10.1176/appi.books.9780890425596</mixed-citation><mixed-citation xml:lang="en">Diagnostic and statistical manual of mental disorders. 5th ed. American Psychiatric Association; 2013. https://doi.org/10.1176/appi.books.9780890425596</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Shattell M., Apostolopoulos Y., Collins C., Sevil S. Trucking organization and mental health disorders of truck drivers. Issues Ment. Health Nurs. 2012; 33(7): 436-44. https://doi.org/10.3109/01612840.2012.665156</mixed-citation><mixed-citation xml:lang="en">Shattell M., Apostolopoulos Y., Collins C., Sevil S. Trucking organization and mental health disorders of truck drivers. Issues Ment. Health Nurs. 2012; 33(7): 436–44. https://doi.org/10.3109/01612840.2012.665156</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Work-related stress, anxiety or depression statistics in Great Britain, 2019. Health and Safety Executive; 2019. Available at: https://www.hse.gov.uk/statistics/causdis/stress.pdf</mixed-citation><mixed-citation xml:lang="en">Work-related stress, anxiety or depression statistics in Great Britain, 2019. Health and Safety Executive; 2019. Available at: https://www.hse.gov.uk/statistics/causdis/stress.pdf</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Tackling work-related stress using the management standards approach. A step-by-step workbook. Health and Safety Executive; 2019.</mixed-citation><mixed-citation xml:lang="en">Tackling work-related stress using the management standards approach. A step-by-step workbook. Health and Safety Executive; 2019.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Sicherheit und Gesundheit bei der Arbeit - Berichtsjahr 2018. Unfallverhütungsbericht Arbeit. Dortmund: Bundesanstalt für Arbeitsschutz und Arbeitsmedizin; 2020. https://doi.org/10.21934/baua:bericht20191115 (in German)</mixed-citation><mixed-citation xml:lang="en">Sicherheit und Gesundheit bei der Arbeit – Berichtsjahr 2018. Unfallverhütungsbericht Arbeit. Dortmund: Bundesanstalt für Arbeitsschutz und Arbeitsmedizin; 2020. https://doi.org/10.21934/baua:bericht20191115 (in German)</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Antares Foundation. Gestion du stress chez les travailleurshumanitaires. Guide de bonnes pratiques. Amsterdam: Pays-Bas; 2012.</mixed-citation><mixed-citation xml:lang="en">Antares Foundation. Gestion du stress chez les travailleurshumanitaires. Guide de bonnes pratiques. Amsterdam: Pays-Bas; 2012.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Stone C., Ding Y. We must continue to tease out the role of stress in the development of disease. Env. Dis. 2016; 1(4): 207-8. https://doi.org/10.4103/2468-5690.198610</mixed-citation><mixed-citation xml:lang="en">Stone C., Ding Y. We must continue to tease out the role of stress in the development of disease. Env. Dis. 2016; 1(4): 207–8. https://doi.org/10.4103/2468-5690.198610</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">EUROGIP. Pathologies psychiques et travail en Europe. Actes des Débatsd’EUROGIP du 24.03.2016. Paris; 2016.</mixed-citation><mixed-citation xml:lang="en">EUROGIP. Pathologies psychiques et travail en Europe. Actes des Débatsd’EUROGIP du 24.03.2016. Paris; 2016.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Bukhtiyarov I.V., Zhovnerchuk E.V., Serikov V.V., Khatin D.E. Cyberphysical diagnosis of risk factors for borderline mental states. Psikhicheskoe zdorov’e. 2020; (8): 30-8. https://doi.org/10.25557/2074-014X.2020.08.30-38 (in Russian)</mixed-citation><mixed-citation xml:lang="en">Bukhtiyarov I.V., Zhovnerchuk E.V., Serikov V.V., Khatin D.E. Cyberphysical diagnosis of risk factors for borderline mental states. Psikhicheskoe zdorov’e. 2020; (8): 30–8. https://doi.org/10.25557/2074-014X.2020.08.30-38 (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Бухтияров И.В., Жовнерчук Е.В., Сериков В.В., Хатин Д.Е. Киберфизическая диагностика факторов риска пограничных психических состояний. Психическое здоровье. 2020; (8): 30-8. https://doi.org/10.25557/2074-014X.2020.08.30-38</mixed-citation><mixed-citation xml:lang="en">Sterling P. Allostasis: A model of predictive regulation. Physiol. Behav. 2012; 106(1): 5–15. https://doi.org/10.1016/j.physbeh.2011.06.004</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Karjalainen A. International statistical classification of diseases and related health problems (ICD-10) in occupational health. WHO/SDE/OEH/99.11. Geneva; 1999. Available at: https://apps.who.int/iris/handle/10665/66100</mixed-citation><mixed-citation xml:lang="en">Karjalainen A. International statistical classification of diseases and related health problems (ICD-10) in occupational health. WHO/SDE/OEH/99.11. Geneva; 1999. Available at: https://apps.who.int/iris/handle/10665/66100</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Freudenberger H.J. Staf burn-out. J. Soc. Iss. 1974; 30: 159-65.</mixed-citation><mixed-citation xml:lang="en">Freudenberger H.J. Staf burn-out. J. Soc. Iss. 1974; 30: 159–65.</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Maslach C. Burned-out. Hum. Behav. 1976; (5): 16-22.</mixed-citation><mixed-citation xml:lang="en">Maslach C. Burned-out. Hum. Behav. 1976; (5): 16–22.</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Maslach C. What have we learned about burnout and health? Psychol. Health. 2001; 16(5): 607-11. https://doi.org/10.1080/08870440108405530</mixed-citation><mixed-citation xml:lang="en">Maslach C. What have we learned about burnout and health? Psychol. Health. 2001; 16(5): 607–11. https://doi.org/10.1080/08870440108405530</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Ahola K. Occupational burnout and health. People and Work Research Reports 81. Helsinki: Finnish Institute of Occupational Health; 2007. Available at: https://www.researchgate.net/publication/47931325</mixed-citation><mixed-citation xml:lang="en">Ahola K. Occupational burnout and health. People and Work Research Reports 81. Helsinki: Finnish Institute of Occupational Health; 2007. Available at: https://www.researchgate.net/publication/47931325</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Schonfeld I.S., Bianchi R. Burnout and depression: Two entities or one? J. Clin. Psychol. 2016; 72(1): 22-37. https://doi.org/10.1002/jclp.22229</mixed-citation><mixed-citation xml:lang="en">Schonfeld I.S., Bianchi R. Burnout and depression: Two entities or one? J. Clin. Psychol. 2016; 72(1): 22–37. https://doi.org/10.1002/jclp.22229</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Andersson G., Cuijpers P. Internet-based and other computerized psychological treatments for adult depression: a meta-analysis. Cogn. Behav. Ther. 2009; 38(4): 196-205. https://doi.org/10.1080/16506070903318960</mixed-citation><mixed-citation xml:lang="en">Andersson G., Cuijpers P. Internet-based and other computerized psychological treatments for adult depression: a meta-analysis. Cogn. Behav. Ther. 2009; 38(4): 196–205. https://doi.org/10.1080/16506070903318960</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Clarke G., Kelleher C., Hornbrook M., Debar L., Dickerson J., Gullion C. Randomized effectiveness trial of an Internet, pure self-help, cognitive behavioral intervention for depressive symptoms in young adults. Cogn. Behav. Ther. 2009; 38(4): 222-34. https://doi.org/10.1080/16506070802675353</mixed-citation><mixed-citation xml:lang="en">Clarke G., Kelleher C., Hornbrook M., Debar L., Dickerson J., Gullion C. Randomized effectiveness trial of an Internet, pure self-help, cognitive behavioral intervention for depressive symptoms in young adults. Cogn. Behav. Ther. 2009; 38(4): 222–34. https://doi.org/10.1080/16506070802675353</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Johansson R., Andersson G. Internet-based psychological treatments for depression. Exp. Rev. Neurother. 2012; 12(7): 861-9. https://doi.org/10.1586/ern.12.63</mixed-citation><mixed-citation xml:lang="en">Johansson R., Andersson G. Internet-based psychological treatments for depression. Exp. Rev. Neurother. 2012; 12(7): 861–9. https://doi.org/10.1586/ern.12.63</mixed-citation></citation-alternatives></ref><ref id="cit65"><label>65</label><citation-alternatives><mixed-citation xml:lang="ru">Karyotaki E., Kleiboer A., Smit F., Turner D.T., Pastor A.M., Andersson G., et al. Predictors of treatment dropout in self-guided web-based interventions for depression: an ‘individual patient data’ meta-analysis. Psychol. Med. 2015; 45(13): 2717-26. https://doi.org/10.1017/S0033291715000665</mixed-citation><mixed-citation xml:lang="en">Karyotaki E., Kleiboer A., Smit F., Turner D.T., Pastor A.M., Andersson G., et al. Predictors of treatment dropout in self-guided web-based interventions for depression: an ‘individual patient data’ meta-analysis. Psychol. Med. 2015; 45(13): 2717–26. https://doi.org/10.1017/S0033291715000665</mixed-citation></citation-alternatives></ref><ref id="cit66"><label>66</label><citation-alternatives><mixed-citation xml:lang="ru">Kolb S., Wengenroth L., Hege I., Praml G., Nowak D., Cantineau J., et al. Case based e-learning in occupational medicine - a European approach. J. Occup. Environ. Med. 2009; 51(6): 647-53.</mixed-citation><mixed-citation xml:lang="en">Kolb S., Wengenroth L., Hege I., Praml G., Nowak D., Cantineau J., et al. Case based e-learning in occupational medicine – a European approach. J. Occup. Environ. Med. 2009; 51(6): 647–53.</mixed-citation></citation-alternatives></ref><ref id="cit67"><label>67</label><citation-alternatives><mixed-citation xml:lang="ru">Schonfeld I.S., Chang C.H. Occupational Health Psychology: Work, Stress and Health. New York, NY: Springer Publishing Co.; 2017.</mixed-citation><mixed-citation xml:lang="en">Schonfeld I.S., Chang C.H. Occupational Health Psychology: Work, Stress and Health. New York, NY: Springer Publishing Co.; 2017.</mixed-citation></citation-alternatives></ref><ref id="cit68"><label>68</label><citation-alternatives><mixed-citation xml:lang="ru">Molen van der H.F., Nieuwenhuijsen K., Frings-Dresen M.H.W., Groene de G. Work-related psychosocial risk factors for stress-related mental disorders: an updated systematic review and meta- analysis. BMJ Open. 2020; 10(7): e034849. https://doi.org/10.1136/bmjopen-2019-034849</mixed-citation><mixed-citation xml:lang="en">Molen van der H.F., Nieuwenhuijsen K., Frings-Dresen M.H.W., Groene de G. Work-related psychosocial risk factors for stress-related mental disorders: an updated systematic review and meta- analysis. BMJ Open. 2020; 10(7): e034849. https://doi.org/10.1136/bmjopen-2019-034849</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
