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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medlit</journal-id><journal-title-group><journal-title xml:lang="ru">Гигиена и санитария</journal-title><trans-title-group xml:lang="en"><trans-title>Hygiene and Sanitation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0016-9900</issn><issn pub-type="epub">2412-0650</issn><publisher><publisher-name>Federal Scientific Center of Hygiene named after F.F. Erisman</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47470/0016-9900-2020-99-2-158-162</article-id><article-id custom-type="elpub" pub-id-type="custom">medlit-202</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГИГИЕНА ТРУДА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OCCUPATIONAL HYGIENE</subject></subj-group></article-categories><title-group><article-title>Оценка зависимости показателей продолжительности жизни от инкорпорации плутония-239 у работников атомной промышленности</article-title><trans-title-group xml:lang="en"><trans-title>Assessment of the relationship between lifetime rates and incorporation of plutonium-235 in atomic production workers</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3509-5372</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тельнов</surname><given-names>Виталий Иванович</given-names></name><name name-style="western" xml:lang="en"><surname>Telnov</surname><given-names>Vitaliy I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат мед. наук, вед. науч. сотр.</p><p>e-mail: tvi@subi.su</p></bio><bio xml:lang="en"><p>MD, Ph.D., DSCi., leading researcher of Southern Urals Biophysics Institute, Ozyorsk, 456780, Chelyabinsk region, Russian Federation.</p><p>e-mail: tvi@subi.su</p></bio><email xlink:type="simple">tvi@subi.su</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4932-7496</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лёгких</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyogkikh</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8260-1808</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Окатенко</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Okatenko</surname><given-names>P. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГУП Южно-Уральский институт биофизики ФМБА России</institution></aff><aff xml:lang="en"><institution>Southern Urals Biophysics Institute of the FMBA of Russia</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>23</day><month>03</month><year>2020</year></pub-date><volume>99</volume><issue>2</issue><fpage>158</fpage><lpage>162</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тельнов В.И., Лёгких И.В., Окатенко П.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Тельнов В.И., Лёгких И.В., Окатенко П.В.</copyright-holder><copyright-holder xml:lang="en">Telnov V.I., Lyogkikh I.V., Okatenko P.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rjhas.ru/jour/article/view/202">https://www.rjhas.ru/jour/article/view/202</self-uri><abstract><sec><title>Введение</title><p>Введение. Целью исследования явилась количественная оценка влияния внутреннего облучения на продолжительность жизни (ПЖ) у работников ПО «Маяк» на основе анализа зависимости ряда показателей ПЖ от инкорпорации плутония-239.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Обследована когорта умерших работников ПО «Маяк» 1948–1958 гг. найма с известным содержанием плутония-239 в организме численностью 2343 человека, в том числе 1739 мужчин и 604 женщины. С помощью регрессионного анализа отдельно у работников разного пола оценивали зависимость общей ПЖ и ПЖ после начала работы (ПЖпнр), а также долю лиц, не доживших до нормативного возраста в целом и после начала работы, от инкорпорации плутония-239. Статистические показатели определяли с использованием программы Statistica.</p></sec><sec><title>Результаты</title><p>Результаты. Установлено, что на 1 кБк инкорпорации плутония-239: у мужчин общая ПЖ сокращается на 0,32, а ПЖпнр – на 0,41 года, у женщин – на 0,22 и 0,28 года соответственно. На 1 кБк инкорпорации плутония-239 у мужчин доля не доживших до 65 лет общей ПЖ и доля не проживших 40 лет после начала работы повышалась на 1,44 и 1,87%, а у женщин – до 70 и 45 лет – на 0,9 и 1,14% соответственно.</p></sec><sec><title>Заключение</title><p>Заключение. Таким образом, у работников зависимость от инкорпорации плутония-239 ПЖпнр была выше, чем общей ПЖ. Доли работников, не доживших до нормативного возраста после начала работы, были больше, чем доли работников, не доживших до общего нормативного возраста. Зависимость сокращения исследованных показателей ПЖ от инкорпорации плутония-239 у мужчин была более выраженной, чем у женщин.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. The objective of the study was the quantitative assessment of the effect of internal exposure to the lifetime in Mayak PA workers based on analyzing the dependence of certain lifetime rates on the incorporation of plutonium-239. </p></sec><sec><title>Material and methods</title><p>Material and methods. There was investigated a cohort of deceased Mayak PA workers employed in 1948-1958 with known Pu-239 body burden comprising 2343 individuals, including 1739 males and 604 females. Using regression analysis we have assessed the dependence of general lifetime and lifetime after the start of work as well as of proportion of individuals who did not survive until standard age in general and after a start of work from incorporated Pu-239 separately for workers of different age. Statistical values were defined using STATISTICA software.</p></sec><sec><title>Results</title><p>Results. It was stated that for 1 kBq of incorporated Pu-239: a general lifetime in males decreased by 0.32 years and after a start of work – by 0.41 years; in females – by 0.22 and 0.28 years respectively. For 1 kBq of incorporated Pu-239 proportion of males who did not survive until 65 years of general lifetime and proportion of males who did not survive 40 years after a start of work increased by 1.33 and 1.87% respectively; in females for 70 and 45 years – by 0.90 and 1.14% respectively.</p></sec><sec><title>Conclusion</title><p>Conclusion. Thus, the workers’ dependence of lifetime after a start of work on incorporated Pu-239 was higher than of a general lifetime. A proportion of workers who did not survive until the standard age after the start of work was higher than the proportion of workers who did not survive until a general standard age. Dependence of decrease of lifetime rates under the study from incorporated Pu-239 in males was more significant than in females.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>работники ПО «Маяк»</kwd><kwd>плутоний-239</kwd><kwd>показатели продолжительности жизни</kwd><kwd>регрессионный анализ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Mayak PA workers</kwd><kwd>Pu-239</kwd><kwd>lifetime values</kwd><kwd>dependence on Pu-239 incorporation</kwd><kwd>regression analysis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ярмоненко С.П., Вайнсон А.А. Радиобиология человека и животных: учебное пособие. М.: Высшая школа; 2004. 549 с.</mixed-citation><mixed-citation xml:lang="en">Yarmonenko S.P., Vaynson A.A. Human and animal radiobiology: textbook [Radiobiologiya cheloveka i zhivotnykh: Uchebnoye posobiye]. Moscow: Vysshaya shkola; 2004. 549 p. 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