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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medlit</journal-id><journal-title-group><journal-title xml:lang="ru">Гигиена и санитария</journal-title><trans-title-group xml:lang="en"><trans-title>Hygiene and Sanitation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0016-9900</issn><issn pub-type="epub">2412-0650</issn><publisher><publisher-name>Federal Scientific Center of Hygiene named after F.F. Erisman</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47470/0016-9900-2022-101-7-765-769</article-id><article-id custom-type="elpub" pub-id-type="custom">medlit-2371</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МЕДИЦИНА ТРУДА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OCCUPATIONAL HEALTH</subject></subj-group></article-categories><title-group><article-title>Анализ поражения периферической нервной системы при вибрационной болезни</article-title><trans-title-group xml:lang="en"><trans-title>Analysis of disorders of the peripheral nervous system in vibration disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6609-8923</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ямщикова</surname><given-names>Анастасия Валерьевна</given-names></name><name name-style="western" xml:lang="en"><surname>Yamshchikova</surname><given-names>Anastasia V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Науч. сотр. лаб. прикладной нейрофизиологии ФГБНУ «Научно-исследовательский институт комплексных проблем гигиены и профессиональных заболеваний», 654041, Новокузнецк.</p><p>e-mail: anastyam@bk.ru</p></bio><bio xml:lang="en"><p>Researcher of the applied neurophysiology laboratory of the Research Institute for Complex Problems of Hygiene and Occupational Diseases, Novokuznetsk, 654041, Russian Federation.</p><p>e-mail: anastyam@bk.ru</p></bio><email xlink:type="simple">anastyam@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8003-036X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гидаятова</surname><given-names>М. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Gidayatova</surname><given-names>Margarita O.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2823-4074</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Флейшман</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Fleishman</surname><given-names>Arnold N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6804-2966</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кунгурова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kungurova</surname><given-names>Alla A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт комплексных проблем гигиены и профессиональных заболеваний»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute for Complex Problems of Hygiene and Occupational Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>10</day><month>08</month><year>2022</year></pub-date><volume>101</volume><issue>7</issue><fpage>765</fpage><lpage>769</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ямщикова А.В., Гидаятова М.О., Флейшман А.Н., Кунгурова А.А., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Ямщикова А.В., Гидаятова М.О., Флейшман А.Н., Кунгурова А.А.</copyright-holder><copyright-holder xml:lang="en">Yamshchikova A.V., Gidayatova M.O., Fleishman A.N., Kungurova A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rjhas.ru/jour/article/view/2371">https://www.rjhas.ru/jour/article/view/2371</self-uri><abstract><sec><title>Введение</title><p>Введение. В профпатологии многие годы применяется исследование функциональных нарушений периферической нервной системы при различных профессиональных заболеваниях. Изучение структурных изменений нервов описано лишь в единичных публикациях. В то же время комплексный структурно-функциональный подход позволяет расширить возможности дифференциальной диагностики вибрационных нейропатий.</p></sec><sec><title>Цель исследования</title><p>Цель исследования: изучить структурно-функциональные нарушения периферической нервной системы у шахтёров с вибрационной болезнью, обусловленной воздействием локальной вибрации.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Обследованы 136 шахтёров с установленным диагнозом вибрационной болезни от воздействия локальной вибрации и 60 человек, никогда не работавших в условиях воздействия производственной вибрации. Всем респондентам было проведено комплексное электронейромиографическое и ультразвуковое исследование периферических нервов верхних конечностей.</p></sec><sec><title>Результаты</title><p>Результаты. Выявлены как функциональные нарушения периферических нервов в виде преимущественно дистальной полинейропатии верхних конечностей, так и структурные изменения в виде локального утолщения нервов на уровне анатомических туннелей. При этом определена корреляционная зависимость между изменёнными функциональными и структурными показателями. Установлено, что у 47,1% шахтёров вибрационные полинейропатии осложнялись компрессией нервов.</p></sec><sec><title>Ограничения исследования</title><p>Ограничения исследования. Исследование ограничено изучением электрофизиологических и сонографических характеристик периферической нервной системы у 136 пациентов с вибрационной болезнью, обусловленной воздействием локальной вибрации.</p></sec><sec><title>Заключение</title><p>Заключение. Комплексное электронейромиографическое и ультразвуковое исследование нервов верхних конечностей у пациентов с вибрационной болезнью позволяет выявить компрессионные нейропатии в виде сочетания локального утолщения нерва и нарушения проведения на уровне туннеля, а также даёт новые возможности дифференциальной диагностики вибрационных полинейропатий.</p><p>Соблюдение этических стандартов. Исследование выполнено неинвазивными методами и соответствует этическим стандартам биоэтического комитета НИИ комплексных проблем гигиены и профессиональных заболеваний, разработанным в соответствии с Хельсинкской декларацией Всемирной медицинской ассоциации «Этические принципы проведения научных исследований с участием человека» с поправками 2013 г. и «Правилами клинической практики в Российской Федерации», утверждёнными приказом Минздрава России № 266 от 19.06.2003 г.</p></sec><sec><title>Участие авторов</title><p>Участие авторов: Ямщикова А.В. — концепция и дизайн исследования, сбор и обработка данных, сбор данных литературы, статистическая обработка, написание текста; Гидаятова М.О. — сбор и обработка данных; Флейшман А.Н. — редактирование; Кунгурова А.А. — сбор и обработка данных. Все соавторы — утверждение окончательного варианта статьи, ответственность за целостность всех частей статьи.</p></sec><sec><title>Конфликт интересов</title><p>Конфликт интересов. Авторы декларируют отсутствие явных и потенциальных конфликтов интересов в связи с публикацией данной статьи.</p></sec><sec><title>Финансирование</title><p>Финансирование. Исследование не имело финансовой поддержки.</p></sec><sec><title>Поступила</title><p>Поступила: 17.03.2022 / Принята к печати: 08.06.2022 / Опубликована: 31.07.2022</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. In occupational pathology, the study of functional disorders of the peripheral nervous system in various occupational diseases has been used for many years. The study of structural changes of nerves is described only in isolated publications. At the same time, a comprehensive structural and functional approach allows expanding the possibilities of differential diagnosis of vibration neuropathies.</p><p>The aim of the study was to investigate structural and functional disorders of the peripheral nervous system in miners with vibration disease due to the exposure of local vibration.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. One hundred thirty-six miners with a proven diagnosis of vibration disease due to the exposure of local vibration and 60 people who had never worked under the conditions of exposure to industrial vibration were examined. All respondents underwent a comprehensive electroneuromyographic and ultrasound investigation of the peripheral nerves of the upper extremities.</p></sec><sec><title>Results</title><p>Results. The study revealed both functional disorders of peripheral nerves in the form of predominantly distal polyneuropathy of the upper extremities and structural changes in the form of local nerve thickening at the level of anatomical tunnels. At the same time, the correlation between the changed functional and structural indices was determined. In 47.1% of the miners, vibration polyneuropathies was found to be complicated by nerve compression.</p></sec><sec><title>Limitations</title><p>Limitations. The investigation is limited to the study of electrophysiological and sonographic characteristics of the peripheral nervous system in 136 patients with vibration disease due to local vibration exposure.</p></sec><sec><title>Conclusion</title><p>Conclusion. Complex electroneuromyographic and ultrasound investigation of the nerves of the upper extremities in the patients with vibration disease allows identifying compression neuropathies in the form of a combination of local nerve thickening and impaired conduction at the tunnel level, and also provides new opportunities for differential diagnosis of vibration polyneuropathies.</p><p>Compliance with ethical standards. the study was carried out with the informed consent of the subjects and complies with the ethical standards of the Bioethical Committee of the Research Institute for Complex Problems of Hygiene and Occupational Diseases, developed in accordance with the Declaration of Helsinki by the World Association “Ethical Principles for Conducting Scientific Research with Human Participation” as amended in 2013 and “Rules of Clinical Practice in the Russian Federation” approved by the Order of the Ministry of Health of the Russian Federation No. 266 dated June 19, 2003.</p></sec><sec><title>Contribution</title><p>Contribution: Yamshchikova A.V. — the concept and design of the study, collection and processing of material, collection of literature data, statistical processing, writing a text; Gidayatova M.O. — collection and processing of material; Fleishman A.N. — editing; Kungurova A.A. — collection and processing of material. All authors are responsible for the integrity of all parts of the manuscript and approval of the manuscript final version.</p></sec><sec><title>Conflict of interest</title><p>Conflict of interest. The authors declare no conflict of interest.</p></sec><sec><title>Acknowledgement</title><p>Acknowledgement. The study had no sponsorship.</p></sec><sec><title>Received</title><p>Received: March 03, 2022 / Accepted: June 08, 2022 / Published: July 31, 2022</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>вибрационная болезнь</kwd><kwd>полинейропатия</kwd><kwd>вибрационная полинейропатия</kwd><kwd>компрессионные нейропатии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>vibration disease</kwd><kwd>polyneuropathy</kwd><kwd>vibration polyneuropathy</kwd><kwd>compression neuropathies</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Фаздалова М.Р., Хайруллина Л.Х. 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