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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medlit</journal-id><journal-title-group><journal-title xml:lang="ru">Гигиена и санитария</journal-title><trans-title-group xml:lang="en"><trans-title>Hygiene and Sanitation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0016-9900</issn><issn pub-type="epub">2412-0650</issn><publisher><publisher-name>Federal Scientific Center of Hygiene named after F.F. Erisman</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47470/0016-9900-2020-99-1-109-114</article-id><article-id custom-type="elpub" pub-id-type="custom">medlit-240</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЗДОРОВЬЕ НАСЕЛЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>POPULATION HEALTH</subject></subj-group></article-categories><title-group><article-title>Анализ и профилактика нежелательных реакций на лекарственные препараты, применяемые в стоматологии</article-title><trans-title-group xml:lang="en"><trans-title>Analysis and prevention of adverse responses to drugs used in dentistry</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3665-1916</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Власова</surname><given-names>Наталья Николаевна</given-names></name><name name-style="western" xml:lang="en"><surname>Vlasova</surname><given-names>Natalia N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат мед. наук, доцент кафедры терапевтической стоматологии ФГАОУ Первый МГМУ имени И.М. Сеченова (Сеченовский университет), 119991, Москва.</p><p>e-mail: vlasova12345@yandex.ru</p></bio><bio xml:lang="en"><p>MD, Ph.D., Associate professor, Department of the therapeutic dentistry оf the I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, 119991, Russian Federation.</p><p>e-mail: vlasova12345@yandex.ru</p></bio><email xlink:type="simple">vlasova12345@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8526-7147</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сологова</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Sologova</surname><given-names>S. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7434-9481</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Терёшкина</surname><given-names>О. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Tereshkina</surname><given-names>O. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1569-8080</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сохова</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sochova</surname><given-names>I. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7047-1436</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чубарев</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Chubarev</surname><given-names>V. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4510-2890</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прохоров</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Prokhorov</surname><given-names>N. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6376-7802</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сологова</surname><given-names>Д. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Sologova</surname><given-names>D. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ Первый МГМУ имени И.М. Сеченова (Сеченовский университет)</institution></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University (Sechenov University)</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>30</day><month>01</month><year>2020</year></pub-date><volume>99</volume><issue>1</issue><fpage>109</fpage><lpage>114</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Власова Н.Н., Сологова С.С., Терёшкина О.И., Сохова И.А., Чубарев В.Н., Прохоров Н.И., Сологова Д.И., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Власова Н.Н., Сологова С.С., Терёшкина О.И., Сохова И.А., Чубарев В.Н., Прохоров Н.И., Сологова Д.И.</copyright-holder><copyright-holder xml:lang="en">Vlasova N.N., Sologova S.S., Tereshkina O.I., Sochova I.A., Chubarev V.N., Prokhorov N.I., Sologova D.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rjhas.ru/jour/article/view/240">https://www.rjhas.ru/jour/article/view/240</self-uri><abstract><p>Наряду с пользой лекарственные средства могут оказывать и неблагоприятные побочные воздействия, выявить причины которых бывает достаточно проблематично в практике врача-стоматолога ввиду многообразия клинической картины. Рациональный приём и оптимальный выбор лекарственного препарата среди большого спектра лекарственных средств зависят от профиля его эффективности и безопасности, лекарственного взаимодействия, индивидуальных особенностей пациента (генетического полиморфизма), иных сопутствующих заболеваний. В современном мире практику врача-стоматолога невозможно представить без применения лекарственных препаратов. Лекарственные средства позволяют врачам оказывать качественную медицинскую помощь, соответствующую мировым стандартам, но не стоит забывать, что при назначении лекарственного препарата крайне важно учитывать, насколько рационально и необходимо его использование для достижения положительного результата. Поэтому изучение профилактики развития нежелательных побочных реакций на лекарственные препараты в стоматологии является важной темой, требующей пристального внимания. На основании проведённого анализа литературы по базам данных РИНЦ, Scopus, Web of Science, MedLine было установлено, что наиболее часто назначаемыми группами лекарственных средств в стоматологии являются: нестероидные противовоспалительные средства (НПВС), местноанестезирующие, противомикробные, антисептические, лекарственные средства. </p><p>Цель исследования: на основании анализа современной информации о нежелательных реакциях на ЛС, часто применяемых в стоматологии, оптимизировать подходы к рациональному применению и профилактике развития нежелательных побочных эффектов.</p></abstract><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>стоматология</kwd><kwd>фармакология</kwd><kwd>нестероидные противовоспалительные средства</kwd><kwd>местные анестетики</kwd><kwd>противомикробные препараты</kwd><kwd>нежелательные реакции</kwd><kwd>обзор литературы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>dentistry</kwd><kwd>pharmacology</kwd><kwd>nonsteroidal anti-inflammatory drugs</kwd><kwd>local anesthetics</kwd><kwd>antibiotics</kwd><kwd>chemotherapeutic drugs</kwd><kwd>adverse reactions</kwd><kwd>side effects</kwd><kwd>literature review</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Астахова А.В., Лепахин В.К. 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