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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medlit</journal-id><journal-title-group><journal-title xml:lang="ru">Гигиена и санитария</journal-title><trans-title-group xml:lang="en"><trans-title>Hygiene and Sanitation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0016-9900</issn><issn pub-type="epub">2412-0650</issn><publisher><publisher-name>Federal Scientific Center of Hygiene named after F.F. Erisman</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18821/0016-9900-2019-98-2-135-141</article-id><article-id custom-type="elpub" pub-id-type="custom">medlit-265</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГИГИЕНА ОКРУЖАЮЩЕЙ СРЕДЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ENVIRONMENTAL HYGIENE</subject></subj-group></article-categories><title-group><article-title>Оценка риска нарушений состояния здоровья у детей, проживающих в зоне влияния производства металлургического глинозёма</article-title><trans-title-group xml:lang="en"><trans-title>Assessment of the risk for health disorders in children who live in a territory of the zone of exposure to production of metallurgical aluminum</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3924-4526</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кольдибекова</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Koldibekova</surname><given-names>Yu. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8013-9613</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Землянова</surname><given-names>Марина Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Zemlyanova</surname><given-names>Marina A.</given-names></name></name-alternatives><bio xml:lang="en"><p>MD, Ph.D., DSCI., Professor, Head of Biochemical and Cytogenetic Diagnostic Techniques Department, Federal Scientific Center for Medical and Preventive Health Risk Management Technologies, Perm, 614045, Russian Federation.</p><p>Е-mail: zem@fcrisk.ru</p></bio><email xlink:type="simple">zem@fcrisk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9075-3257</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Игнатова</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Ignatova</surname><given-names>A. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4111-8454</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тихонова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tikhonova</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4111-8454</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маркович</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Markovich</surname><given-names>N. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4111-8454</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Четверкина</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Chetverkina</surname><given-names>K. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6316-7850</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ухабов</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Ukhabov</surname><given-names>V. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФБУН «Федеральный научный центр медико-профилактических технологий управления рисками здоровью населения» Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека</institution></aff><aff xml:lang="en"><institution>Federal Scientific Center for Medical and Preventive Health Risk Management Technologies</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФБУН «Федеральный научный центр медико-профилактических технологий управления рисками здоровью населения» Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека; ФГБОУ ВО «Пермский научно-исследовательский политехнический университет»</institution></aff><aff xml:lang="en"><institution>Federal Scientific Center for Medical and Preventive Health Risk Management Technologies; Perm Research Polytechnic University</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Управление Роспотребнадзора по Красноярскому краю</institution></aff><aff xml:lang="en"><institution>Management of Rospotrebnadzor in the Krasnoyarsk Territory</institution></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБОУ ВО «Пермский государственный медицинский университет имени академика Е.А. Вагнера»</institution></aff><aff xml:lang="en"><institution>E.A. Wagner Perm State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>14</day><month>10</month><year>2020</year></pub-date><volume>98</volume><issue>2</issue><fpage>135</fpage><lpage>141</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кольдибекова Ю.В., Землянова М.А., Игнатова А.М., Тихонова И.В., Маркович Н.И., Четверкина К.В., Ухабов В.М., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Кольдибекова Ю.В., Землянова М.А., Игнатова А.М., Тихонова И.В., Маркович Н.И., Четверкина К.В., Ухабов В.М.</copyright-holder><copyright-holder xml:lang="en">Koldibekova Y.V., Zemlyanova M.A., Ignatova A.M., Tikhonova I.V., Markovich N.I., Chetverkina K.V., Ukhabov V.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rjhas.ru/jour/article/view/265">https://www.rjhas.ru/jour/article/view/265</self-uri><abstract><sec><title>Введение</title><p>Введение. Наиболее высокие уровни загрязнения атмосферного воздуха стабильно отмечаются в промышленно-развитых регионах, лидирующими из которых являются регионы с активным производством продукции цветной металлургии. </p></sec><sec><title>Материал и методы</title><p>Материал и методы. Объектами исследования явились пробы атмосферного воздуха территории с размещением предприятия по производству металлургического глинозёма и территории с отсутствием изучаемого производства, базы данных по заболеваемости детского населения, материалы по оценке неканцерогенного риска и численности экспонированного населения, результаты эпидемиологического обследования. </p></sec><sec><title>Результаты</title><p>Результаты. Неудовлетворительное качество атмосферного воздуха по содержанию взвешенных веществ, твёрдых частиц РМ10, диоксида азота, диоксида серы и постоянное присутствие соединений марганца, никеля, меди, обусловленное хозяйственной деятельностью объектов производства металлургического глинозёма, формируют неприемлемый риск развития неканцерогенных эффектов в отношении органов дыхания. Значительный вклад в величину индекса опасности формируют взвешенные вещества, частицы РМ10, РМ2,5. Мелкодисперсная фракция характеризуется сложным химическим составом (оксиды железа, алюминия, кремния, никеля, хрома, титана, марганца), что может усугублять негативное действие идентифицированных факторов риска на органы дыхания. Распространённость заболеваний органов дыхания детского населения в зоне экспозиции подтверждает реализацию внешнесредовых рисков в части формирования повышенного уровня общей и первичной заболеваемости. Доказаны зависимости вероятности возникновения заболеваний органов дыхания у детей от содержания в атмосферном воздухе изучаемых веществ, в том числе взвешенных веществ и мелкодисперсных фракций РМ10, РМ2,5, азота оксида, азота диоксида, серы диоксида, соединений марганца, никеля, меди. </p></sec><sec><title>Выводы</title><p>Выводы. В селитебной застройке в зоне влияния хозяйственной деятельности объекта по производству металлургического глинозёма у детей формируется хронический аэрогенный риск развития заболеваний органов дыхания, реализация которого выявляется в виде повышенного уровня заболеваемости болезнями органов дыхания, доказано связанного с воздействием взвешенных веществ и мелкодисперсных фракций РМ10, РМ2,5, азота оксида, азота диоксида, серы диоксида, марганца, никеля, меди.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. The atmospheric air is known to be the most contaminated on territories where industries are highly developed; non-ferrous metallurgy is one of them that make the greatest contribution into atmospheric air contamination. </p></sec><sec><title>Data and methods</title><p>Data and methods. Our research objects were air samples taken on territories where there was located an enterprise producing metallurgic aluminum and our reference samples were taken on a territory where there was no such production; we also examined databases containing data on morbidity of children population, non-carcinogenic risk assessment, number of exposed population, and the results of epidemiologic examination. </p></sec><sec><title>Results</title><p>Results. Quality of the atmospheric air was unsatisfactory as there were concentrations of suspended substances, PM10 solid particles, nitrogen dioxide, sulfur dioxide, as well as persistence occurrence of manganese, nickel, and copper compounds resulted from activities of enterprises that produced metallurgic aluminum. All the above-mentioned admixtures cause an unacceptable risk of non-carcinogenic effects emerging in the respiratory organs. A significant contribution into hazard index is made by suspended substances, PM10 and PM2.5 particles. Fine-dispersed fraction having a complicated chemical structure (ferric oxides; aluminum, silicon, nickel, chromium, titanium, and manganese oxides), can aggravate negative impacts on the respiratory organs, exerted by the identified risk factors. The prevalence of respiratory organs diseases among children population living on an exposed territory confirms environmental risks to make increased levels of the overall and primary morbidity rate. We proved a probability of respiratory organs diseases to be depended on concentrations of the examined substances in the atmosphere, including suspended substances and fine-dispersed fractions of PM10 and PM2.5, nitrogen oxide, nitrogen dioxide, sulfur dioxide, compounds of nickel, manganese, and copper. </p></sec><sec><title>Discussion</title><p>Discussion. The detected cause-and-effect relations between a risk of increased morbidity with respiratory organs diseases in children and exposure to chemical risk factors, primarily suspended particles, PM10 and PM2.5, are also confirmed by results obtained in a number of research that concentrates on peculiarities of effects produced by the examined chemical factors on respiratory organs diseases in children. </p></sec><sec><title>Conclusions</title><p>Conclusions. Children living on a territory exposed to the exposure exerted by an enterprise that produces metallurgic aluminum have a chronic aerogenic risk for respiratory organs diseases; this risk becomes apparent due to the elevated morbidity rate of respiratory organs diseases. This risk is proved to be related to impacts exerted by suspended substances and fine-dispersed fractions of PM10 and PM2.5, nitrogen oxide, nitrogen dioxide, sulfur dioxide, manganese, nickel, and copper.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>атмосферный воздух</kwd><kwd>взвешенные вещества</kwd><kwd>взвешенные частицы РМ10 и РМ2</kwd><kwd>5</kwd><kwd>производство металлургического глинозема</kwd><kwd>детское население</kwd><kwd>риск здоровью</kwd><kwd>болезни органов дыхания</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atmospheric air</kwd><kwd>suspended substances</kwd><kwd>РМ10 and РМ2</kwd><kwd>5 suspended particles</kwd><kwd>metallurgic aluminum production</kwd><kwd>children population</kwd><kwd>health risk</kwd><kwd>respiratory organs diseases</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Heroux M.E., Braubach M., Korol N., et all. 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