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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medlit</journal-id><journal-title-group><journal-title xml:lang="ru">Гигиена и санитария</journal-title><trans-title-group xml:lang="en"><trans-title>Hygiene and Sanitation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0016-9900</issn><issn pub-type="epub">2412-0650</issn><publisher><publisher-name>Federal Scientific Center of Hygiene named after F.F. Erisman</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47470/0016-9900-2022-101-12-1438-1442</article-id><article-id custom-type="elpub" pub-id-type="custom">medlit-2740</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГИГИЕНА ОКРУЖАЮЩЕЙ СРЕДЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ENVIRONMENTAL HYGIENE</subject></subj-group></article-categories><title-group><article-title>Метеореакции у лиц с заболеваниями органов дыхания, проживающих в условиях морского климата Владивостока</article-title><trans-title-group xml:lang="en"><trans-title>Weather reactions in persons with respiratory diseases who lives in conditions of the marine climate of Vladivostok</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6372-6560</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Веремчук</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Veremchuk</surname><given-names>Ludmila V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1009-9011</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Виткина</surname><given-names>Т. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Vitkina</surname><given-names>Tatyana I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4286-2827</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Минеева</surname><given-names>Е. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Mineeva</surname><given-names>Elena E.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7582-343X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барскова</surname><given-names>Людмила Сергеевна</given-names></name><name name-style="western" xml:lang="en"><surname>Barskova</surname><given-names>Lyudmila S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Канд. мед. наук, мл. науч. сотр. лаб. медицинской экологии и рекреационных ресурсов Владивостокского филиала ДНЦ ФПД — НИИМКВЛ.</p><p>e-mail: pretty_people_2016@mail.ru</p></bio><bio xml:lang="en"><p>Junior Researcher of Laboratory of Medical Ecology and Recreational Resources of Vladivostok branch of Vladivostok Branch of Far Eastern Scientific Centre of Physiology and Pathology of Respiration — Scientific Research Institute of Medical Climatology and Rehabilitation Treatment, Vladivostok, 690105, Russian Federation.</p><p>e-mail: pretty_people_2016@mail.ru</p></bio><email xlink:type="simple">pretty_people_2016@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6413-9840</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гвозденко</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gvozdenko</surname><given-names>Tatyana A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Владивостокский филиал ФГБНУ «Дальневосточный научный центр физиологии и патологии дыхания» — Научно-исследовательский институт медицинской климатологии и восстановительного лечения</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Vladivostok Branch of Far Eastern Scientific Centre of Physiology and Pathology of Respiration — Scientific Research Institute of Medical Climatology and Rehabilitation Treatment</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>13</day><month>01</month><year>2023</year></pub-date><volume>101</volume><issue>12</issue><fpage>1438</fpage><lpage>1442</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Веремчук Л.В., Виткина Т.И., Минеева Е.Е., Барскова Л.С., Гвозденко Т.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Веремчук Л.В., Виткина Т.И., Минеева Е.Е., Барскова Л.С., Гвозденко Т.А.</copyright-holder><copyright-holder xml:lang="en">Veremchuk L.V., Vitkina T.I., Mineeva E.E., Barskova L.S., Gvozdenko T.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rjhas.ru/jour/article/view/2740">https://www.rjhas.ru/jour/article/view/2740</self-uri><abstract><sec><title>Введение</title><p>Введение. Высокий уровень распространения заболеваний органов дыхания во многом связан с изменением климата. Нарушение адаптационно-компенсаторных возможностей организма, вызывающее неадекватное реагирование гомеостатических систем, во многом определяется краткосрочной метеореакцией человека на резко меняющиеся условия погодного режима.</p><p>Целью работы явилось изучение интенсивности краткосрочной метеореакции системы внешнего дыхания, сердечно-сосудистой и иммунной систем организма у лиц с заболеваниями органов дыхания, проживающих в морском муссонном климате г. Владивостока, для разработки программы профилактических мероприятий.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Исследование включало контрольную группу (163 человека), лиц с бронхиальной астмой (БА) (221 человек) и хронической обструктивной болезнью лёгких (ХОБЛ) (148 человек). Оценивалась краткосрочная (± 1 день) метеореакция функции внешнего дыхания, сердечно-сосудистой и иммунной систем. День обследования оценивался как синхронная метеореакция, за 1 день до обследования — последовая и 1 день после — сигнальная реакция. Рассчитывали интегральный показатель (Дм%), определяющий процентное соотношение корреляционных связей (r при p &lt; 0,05) относительно общей суммы (r) в корреляционной матрице.</p></sec><sec><title>Результаты</title><p>Результаты. Компенсаторные возможности сердечно-сосудистой, респираторной и иммунной систем при воздействии погодных условий у здорового населения города значительно выше, чем у лиц с ХОБЛ и БА. Межсуточные изменения погодных условий оказывают наибольшее негативное воздействие на систему внешнего дыхания, особенно у больных БА и ХОБЛ. Отмечена наименьшая резистентность организма при синхронном действии метеокомпонентов. Наибольший компенсаторный ответ установлен при сигнальной метеореакции.</p></sec><sec><title>Ограничения исследования</title><p>Ограничения исследования. Ограничением является то, что наше исследование характеризует метеореакцию на конкретной территории в условиях морского муссонного климата.</p></sec><sec><title>Заключение</title><p>Заключение. Здоровое население города наиболее адаптировано к местному климату. У лиц с заболеваниями органов дыхания наиболее уязвима система внешнего дыхания. В краткосрочном рассмотрении метеореакции синхронная позиция проявляет наибольший негативный эффект на основные функциональные системы.</p><p>Соблюдение этических стандартов. Исследование одобрено Этическим комитетом Владивостокского филиала ДНЦ ФПД — НИИМКВЛ (№ 8/2022 от 20.09.2022 г.).</p></sec><sec><title>Согласие пациентов</title><p>Согласие пациентов. Каждый участник исследования (или его законный представитель) дал информированное добровольное письменное согласие на участие в исследовании и публикацию персональной медицинской информации в обезличенной форме в журнале «Гигиена и санитария».</p></sec><sec><title>Участие авторов</title><p>Участие авторов: Веремчук Л.В. — концепция и дизайн исследования, сбор и обработка материала; Виткина Т.И. — концепция и дизайн исследования, сбор и обработка материала; Минеева Е.Е. — набор клинических групп, функциональные исследования, сбор и обработка материала; Барскова Л.С. — статистическая обработка; Гвозденко Т.А. — сбор данных литературы, ответственность за целостность всех частей статьи. Все соавторы — написание текста, редактирование, утверждение окончательного варианта статьи.</p></sec><sec><title>Конфликт интересов</title><p>Конфликт интересов. Авторы декларируют отсутствие явных и потенциальных конфликтов интересов в связи с публикацией данной статьи.</p></sec><sec><title>Финансирование</title><p>Финансирование. Исследование не имело спонсорской поддержки.</p></sec><sec><title>Поступила</title><p>Поступила: 11.10.2022 / Принята к печати: 08.12.2022 / Опубликована: 12.01.2023</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. The high prevalence of respiratory diseases is largely due to climate change. Violation of the adaptive-compensatory capabilities of the body, causing an inadequate response of homeostatic systems, is largely determined by a person’s short-term meteorological response to dramatically changing weather conditions.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The study included a control group (one hundred sixty three people), individuals with bronchial asthma (BA) (221 case) and chronic obstructive pulmonary disease (COPD) (148 patients). Short-term (± 1 day) meteor reaction of the respiratory function, cardiovascular and immune systems was assessed. The day of the examination was evaluated as a synchronous meteorological reaction, 1 day before the examination — a follow-up and 1 day after — a signal reaction. There was calculated an integral indicator (Dm%) which determines the percentage of correlations (r at p&lt;0.05) relative to the total amount (r) in the correlation matrix.</p></sec><sec><title>Results</title><p>Results. The compensatory capabilities of the cardio-respiratory and immune systems under the influence of weather conditions in the healthy population of the city are significantly higher than in COPD and BA cases. Day-to-day changes in weather conditions have the greatest negative impact on the respiratory system, especially in BA and COPD patients The least resistance of the organism was noted under the synchronous action of meteorological components. The greatest compensatory response was established during the signal meteoreaction.</p></sec><sec><title>Limitations</title><p>Limitations. A limitation is that the study identified a meteorological response in a specific area under a maritime monsoonal climate.</p></sec><sec><title>Conclusion</title><p>Conclusion. The healthy population of the city is the most adapted to the local climate. In persons with respiratory diseases, the system of external respiratory is the most vulnerable. In the short-term consideration of the weather-induced reaction, the synchronous position exhibits the greatest negative effect on the main functional systems.</p><p>Compliance with ethical standards. The study was approved by the Ethics Committee of the Vladivostok branch of the Far Eastern Scientific Centre of Physiology and Pathology of Respiration — Scientific Research Institute of Medical Climatology and Rehabilitation Treatment (№ 8/2022, 20.09.2022).</p></sec><sec><title>Patient consent</title><p>Patient consent. Each participant of the study (or his/her legal representative) gave informed voluntary written consent to participate in the study and publish personal medical information in an impersonal form in the journal "Gigiena i Sanitariya (Hygiene and Sanitation, Russian journal)".</p></sec><sec><title>Contribution</title><p>Contribution: Veremchuk L.V. — the concept and design of the study, the collection and processing of material; Vitkina T.I. — the concept and design of the study, the collection and processing of material; Mineeva E.E. — a set of clinical groups, functional studies, collection and processing of material; Barskova L.S. — statistical processing; Gvozdenko T.A. — collection of literature data, responsibility for the integrity of all parts of the article. All authors are responsible for the integrity of all parts of the manuscript and approval of the manuscript final version. </p></sec><sec><title>Conflict of interest</title><p>Conflict of interest. The authors declare no conflict of interest. </p></sec><sec><title>Acknowledgement</title><p>Acknowledgement. The study had no sponsorship. </p></sec><sec><title>Received</title><p>Received: October 11, 2022 / Accepted: December 8, 2022 / Published: January 12, 2023 </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>метеореакция</kwd><kwd>сердечно-сосудистая система</kwd><kwd>респираторная система</kwd><kwd>иммунная система</kwd><kwd>бронхолёгочная патология</kwd><kwd>муссонный климат</kwd></kwd-group><kwd-group xml:lang="en"><kwd>weather-induced reaction</kwd><kwd>cardiovascular</kwd><kwd>respiratory</kwd><kwd>immune systems</kwd><kwd>bronchopulmonary pathology</kwd><kwd>monsoon climate</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ревич Б.А., Шапошников Д.А. 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