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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medlit</journal-id><journal-title-group><journal-title xml:lang="ru">Гигиена и санитария</journal-title><trans-title-group xml:lang="en"><trans-title>Hygiene and Sanitation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0016-9900</issn><issn pub-type="epub">2412-0650</issn><publisher><publisher-name>Federal Scientific Center of Hygiene named after F.F. Erisman</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47470/0016-9900-2023-102-9-962-967</article-id><article-id custom-type="edn" pub-id-type="custom">mhjhin</article-id><article-id custom-type="elpub" pub-id-type="custom">medlit-3429</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГИГИЕНА ДЕТЕЙ И ПОДРОСТКОВ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>HYGIENE OF CHILDREN AND ADOLESCENTS</subject></subj-group></article-categories><title-group><article-title>Оценка аэрогенного риска у мальчиков-подростков при различных уровнях физической активности</article-title><trans-title-group xml:lang="en"><trans-title>Assessment of the aerogenic risk in adolescent boys at various levels of physical activity</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7218-2147</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ефимова</surname><given-names>Наталья Васильевна</given-names></name><name name-style="western" xml:lang="en"><surname>Efimova</surname><given-names>Natalya V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор мед. наук, профессор, вед. науч. сотр. лаб. эколого-гигиенических исследований ФГБНУ «Восточно-Сибирский институт медико-экологических исследований», 665826, Ангарск.</p><p>e-mail: medecolab@inbox.ru</p></bio><bio xml:lang="en"><p>MD, PhD, DSci, Professor, a leading researcher of the Laboratory of environmental and health studies East-Siberian Institute of Medical and Ecological Research, East-Siberian Institute of Medical and Ecological Research, Angarsk, 665827, Russian Federation.</p><p>e-mail: medecolab@inbox.ru</p></bio><email xlink:type="simple">medecolab@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0169-4513</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мыльникова</surname><given-names>Инна В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mylnikova</surname><given-names>Inna V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6809-4707</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кудаев</surname><given-names>Андрей Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kudaev</surname><given-names>Andrey N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Восточно-Сибирский институт медико-экологических исследований»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>East-Siberian Institute of Medical and Ecological Research</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>28</day><month>10</month><year>2023</year></pub-date><volume>102</volume><issue>9</issue><fpage>962</fpage><lpage>967</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ефимова Н.В., Мыльникова И.В., Кудаев А.Н., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Ефимова Н.В., Мыльникова И.В., Кудаев А.Н.</copyright-holder><copyright-holder xml:lang="en">Efimova N.V., Mylnikova I.V., Kudaev A.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rjhas.ru/jour/article/view/3429">https://www.rjhas.ru/jour/article/view/3429</self-uri><abstract><sec><title>Введение</title><p>Введение. Аэрогенное воздействие химических веществ даже при коротком режиме воздействия может способствовать формированию нарушений основных регуляторных систем организма.</p><p>Цель работы — дать оценку аэрогенного риска для здоровья мальчиков-подростков при различных уровнях физической активности в условиях краткосрочного, но регулярного режима воздействия.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Содержание химических веществ в воздухе спортивных залов общеобразовательных и спортивных школ оценивали по данным разовых проб, расчёт риска — по средним величинам проб, отобранных в течение 1 ч. Сценарии оценки риска учитывали соматометрические показатели мальчиков 13–17 лет, частоту и уровни интенсивности физической активности.</p></sec><sec><title>Результаты</title><p>Результаты. Соматометрические показатели у мальчиков с умеренным и интенсивным уровнем физической активности находились в интервалах возрастной нормы. Концентрации взвешенных веществ, диоксидов серы и азота, формальдегида в воздухе спортивных залов соответствовали гигиеническим нормативам. Аэрогенный риск для мальчиков с умеренным уровнем физической активности составил в покое HI = 1,5–1,9, после физической нагрузки HI = 1,9–2,3; с интенсивным уровнем — HI = 2,1–4 и HI = 3,9–7 соответственно. Таким образом, уровень физической активности, время, проводимое в помещениях для занятий спортом, в сочетании с бо́льшими показателями спирометрии приводят к увеличению аэрогенного риска. Величина HI как в покое, так и после физической нагрузки на 57–58,9% определяется содержанием взвешенных веществ, в том числе PM2,5 = 30–32%, PM10 = 25–26,9%.</p><p>Ограничения исследования обусловлены тем, что при оценке индекса опасности учтены не все химические вещества, которые могут присутствовать в воздухе спортивных помещений.</p></sec><sec><title>Заключение</title><p>Заключение. Проведённое исследование свидетельствует о необходимости мониторинга химических веществ, содержащихся в воздушной среде спортивных помещений, и изучения влияния химических веществ на состояние дыхательной, сердечно-сосудистой и нервной систем юношей с учётом уровня физической активности.</p><p>Соблюдение этических стандартов. Исследование одобрено Этическим комитетом ФГБНУ ВСИМЭИ (заключение ЛЭК № 1 от 27.01.2022 г.).</p></sec><sec><title>Участие авторов</title><p>Участие авторов:Ефимова Н.В. — концепция и дизайн исследования, написание текста;Мыльникова И.В. — статистическая обработка данных, написание текста;Кудаев А.Н. — организация исследования, сбор материала, статистическая обработка данных.Все соавторы — утверждение окончательного варианта статьи, ответственность за целостность всех частей статьи.</p></sec><sec><title>Конфликт интересов</title><p>Конфликт интересов. Авторы декларируют отсутствие явных и потенциальных конфликтов интересов в связи с публикацией данной статьи.</p></sec><sec><title>Финансирование</title><p>Финансирование. Работа выполнена в рамках средств, выделяемых для выполнения государственного задания ФГБНУ ВСИМЭИ.</p></sec><sec><title>Поступила</title><p>Поступила: 01.06.2023 / Принята к печати: 26.09.2023 / Опубликована: 30.10.2023</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Aerogenic exposure to chemicals can contribute to the formation of violations of the main regulatory systems of the body.</p><p>The aim is to assess the aerogenic risk to the health in adolescent boys at various levels of physical activity.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The content of chemicals in the air of sports halls of general education and sports schools was assessed by single samples, the risk was calculated from the average values of samples taken over 1 hour. The risk is calculated for young 13–17 years boys, taking into account somatometric indicators, the intensity of physical activity.</p></sec><sec><title>Results</title><p>Results. Somatometric indicators of adolescents with moderate and intense levels of activity corresponded to the age norm. The concentrations of suspended solids, sulfur dioxide and nitrogen, formaldehyde in the air of sports halls met the hygienic standards. An aerogenic risk at a moderate level of activity corresponded to hazard index (HI) = 1.5–1.9 at rest, HI = 1.9–2.3 after exercise; intensive level – HI=2.1–4 and HI=3.9–7, respectively. The value of HI at rest and after exercise by 57–58.9% is determined by the content of suspended solids, including PM2.5 = 30–32%, PM10 = 25–26.9%.</p><p>Limitations of the study are due to the fact that when assessing the hazard index, not all chemicals that may be present in the air of sports facilities are taken into account.</p></sec><sec><title>Conclusion</title><p>Conclusion. The study points to the need to control chemicals in the air of sports facilities and study the effect of chemicals on the state of the leading systems of adolescents, taking into account the level of physical activity.</p><p>Compliance with ethical standards. The study was approved by the Ethics Committee of the Federal State Budgetary Scientific Institution VSIMEI (conclusion of the LEC No. 1 of January 27, 2022).</p></sec><sec><title>Contribution</title><p>Contribution:Efimova N.V. — the concept and design of the study, writing the text;Mylnikova I.V. — statistical data processing, text writing;Kudaev A.N. — organization of research, collection of material, writing the text.All authors are responsible for the integrity of all parts of the manuscript and approval of the manuscript final version.</p></sec><sec><title>Conflict of interest</title><p>Conflict of interest. The authors declare no conflict of interest.</p></sec><sec><title>Acknowledgement</title><p>Acknowledgement. The study had no sponsorship.</p></sec><sec><title>Received</title><p>Received: June 1, 2023 / Accepted: September 26, 2023 / Published: October 30, 2023</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>аэрогенный риск для здоровья</kwd><kwd>краткосрочное воздействие</kwd><kwd>воздух помещений</kwd><kwd>спортивные залы</kwd><kwd>физическая активность</kwd><kwd>подростки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>aerogenic health risk</kwd><kwd>short term impact</kwd><kwd>indoor air</kwd><kwd>Sport halls</kwd><kwd>physical activity</kwd><kwd>adolescent</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Global action plan on physical activity 2018–2030: more active people for a healthier world. Geneva: World Health Organization; 2018. Available at: https://apps.who.int/iris/bitstream/handle/10665/272722/9789241514187-eng.pdf</mixed-citation><mixed-citation xml:lang="en">Global action plan on physical activity 2018–2030: more active people for a healthier world. Geneva: World Health Organization; 2018. Available at: https://apps.who.int/iris/bitstream/handle/10665/272722/9789241514187-eng.pdf</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Распоряжение Правительства РФ № 3081-р «Стратегия развития физической культуры и спорта в Российской Федерации на период до 2030 года». М.; 2020.</mixed-citation><mixed-citation xml:lang="en">Decree of the Government of the Russian Federation № 3081-r «Strategy for the development of physical culture and sports in the Russian Federation for the period up to 2030». Moscow; 2020. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Бергерон М.Ф., Моунтджой М., Армстронг Н., Чиа М., Коте Ж., Эмери К.А. и др. Подготовка спортивного резерва: рекомендации международного олимпийского комитета. Прикладная спортивная наука. 2017; (1): 122–40. https://elibrary.ru/yuiowl</mixed-citation><mixed-citation xml:lang="en">Bergeron M.F., Mountjoy M., Armstrong N., Chia M., Côté J., Emery C.A., et al. International Olympic Committee consensus statement on youth athletic development. Br. J. Sports Med. 2015; 49(13): 843–51. https://doi.org/10.1136/bjsports-2015-094962</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Кучма В.Р., Соколова С.Б. Основные тренды поведенческих рисков, опасных для здоровья. Анализ риска здоровью. 2019; (2): 4–13. https://doi.org/10.21668/health.risk/2019.2.01 https://elibrary.ru/zxmyvv</mixed-citation><mixed-citation xml:lang="en">Kuchma V.R., Sokolova S.B. Basic trends in behavioral health risks. Analiz riska zdorov’yu. 2019; (2): 4–13. https://doi.org/10.21668/health.risk/2019.2.01.eng https://elibrary.ru/xmcldm</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Попова Е.С., Иванова Н.А. Проблема недостаточной физической активности современных школьников. Проблемы педагогики. 2020; (6): 110–4. https://elibrary.ru/wvzujy</mixed-citation><mixed-citation xml:lang="en">Popova E.S., Ivanova N.A. The problem of insufficient physical activity of modern schoolchildren. Problemy pedagogiki. 2020; (6): 110–4. https://elibrary.ru/wvzujy (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Guthold R., Stevens G.A., Riley L.M., Bull F.C. Global trends in insufficient physical activity among adolescents: a pooled analysis of 298 population-based surveys with 1,6 million participants. Lancet Child Adolesc. Health. 2020; 4(1): 23–35. https://doi.org/10.1016/S2352-4642(19)30323-2</mixed-citation><mixed-citation xml:lang="en">Guthold R., Stevens G.A., Riley L.M., Bull F.C. Global trends in insufficient physical activity among adolescents: a pooled analysis of 298 population-based surveys with 1,6 million participants. Lancet Child Adolesc. Health. 2020; 4(1): 23–35. https://doi.org/10.1016/S2352-4642(19)30323-2</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">de Jesus G.M., de Oliveira Araujo R.H., Dias L.A., Barros A.K.C., Dos Santos Araujo L.D.M., de Assis M.A.A. Attendance in physical education classes, sedentary behavior, and different forms of physical activity among schoolchildren: a cross-sectional study. BMC Public Health. 2022; 22(1): 1461. https://doi.org/10.1186/s12889-022-13864-9</mixed-citation><mixed-citation xml:lang="en">de Jesus G.M., de Oliveira Araujo R.H., Dias L.A., Barros A.K.C., Dos Santos Araujo L.D.M., de Assis M.A.A. Attendance in physical education classes, sedentary behavior, and different forms of physical activity among schoolchildren: a cross-sectional study. BMC Public Health. 2022; 22(1): 1461. https://doi.org/10.1186/s12889-022-13864-9</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">WHO. Health for the World’s Adolescents. A Second Chance in the Second Decade. Copenhagen: WHO Regional Office for Europe; 2012.</mixed-citation><mixed-citation xml:lang="en">WHO. Health for the World’s Adolescents. A Second Chance in the Second Decade. Copenhagen: WHO Regional Office for Europe; 2012.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Маклакова Е.С. Организация и функции семьи в физическом воспитании детей и подростков. Обучение и воспитание: методики и практика. 2016; (30–1): 56–61. https://elibrary.ru/xeigcl</mixed-citation><mixed-citation xml:lang="en">Maklakova E.S. Organization and functions of the family in the physical education of children and adolescents. Obuchenie i vospitanie: metodiki i praktika. 2016; (30–1): 56–61. https://elibrary.ru/xeigcl (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Бабикова А.С., Насыбуллина Г.М. Гигиеническая оценка условий и организации тренировочного процесса в детско-юношеских спортивных школах. Здоровье населения и среда обитания – ЗНиСО. 2018; (12): 41–6. https://doi.org/10.35627/2219-5238/2018-309-12-41-46 https://elibrary.ru/midlwx</mixed-citation><mixed-citation xml:lang="en">Babikova A.S., Nasybullina G.M. Hygienic assessment of conditions and organization of training process in children and youth sports schools. Zdorov’e naseleniya i sreda obitaniya – ZNiSO. 2018; (12): 41–6. https://doi.org/10.35627/2219-5238/2018-309-12-41-46 https://elibrary.ru/midlwx (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Andrade A., Dominski F.H. Indoor air quality of environments used for physical exercise and sports practice: Systematic review. J. Environ. Manage. 2018; 206: 577–86. https://doi.org/10.1016/j.jenvman.2017.11.001</mixed-citation><mixed-citation xml:lang="en">Andrade A., Dominski F.H. Indoor air quality of environments used for physical exercise and sports practice: Systematic review. J. Environ. Manage. 2018; 206: 577–86. https://doi.org/10.1016/j.jenvman.2017.11.001</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Мыльникова И.В., Ефимова Н.В., Кудаев А.Н. Оценка риска, связанного с химическим загрязнением воздушной среды спортивных сооружений, для здоровья детей. Гигиена и санитария. 2022; 101(9): 1086–92. https://doi.org/10.47470/0016-9900-2022-101-9-1086-1092 https://elibrary.ru/srkjuq</mixed-citation><mixed-citation xml:lang="en">Myl’nikova I.V., Efimova N.V., Kudaev A.N. Assessment of the risk associated with chemical pollution of air environment of sports facilities for children’s health. Gigiena i Sanitaria (Hygiene and Sanitation, Russian journal). 2022; 101(9): 1086–92. https://doi.org/10.47470/0016-9900-2022-101-9-1086-1092 https://elibrary.ru/srkjuq (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Цинкер М.Ю. Трехмерное моделирование дыхательной системы человека для задач оценки рисков здоровью при ингаляционной экспозиции химических веществ. Гигиена и санитария. 2016; 95(1): 90–3. https://doi.org/10.18821/0016-9900-2016-95-1-90-93 https://elibrary.ru/vosqvj</mixed-citation><mixed-citation xml:lang="en">Tsinker M.Yu. Three-dimensional modeling of human respiratory system for tasks of health risk assessment in the exposure to the chemicals inhalation. Gigiena i Sanitaria (Hygiene and Sanitation, Russian journal). 2016; 95(1): 90–3. https://doi.org/10.18821/0016-9900-2016-95-1-90-93 https://elibrary.ru/vosqvj (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Шустова С.А., Мирошкина Т.А. Защитные механизмы лёгких. Российский медико-биологический вестник имени академика И.П. Павлова. 2020; 28(4): 567–77. https://doi.org/10.23888/PAVLOVJ2020284567-577 https://elibrary.ru/kdpnhx</mixed-citation><mixed-citation xml:lang="en">Shustova S.A., Miroshkina T.A. Protective mechanisms of lungs. Rossiyskiy mediko-biologicheskiy vestnik imeni akademika I.P. Pavlova. 2020; 28(4): 567–77. https://doi.org/10.23888/PAVLOVJ2020284567-577 https://elibrary.ru/kdpnhx (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Нахратова О.В., Цыганкова Д.П., Баздырев Е.Д. Влияние загрязнения атмосферного воздуха взвешенными частицами на риск сердечно-сосудистых заболеваний (обзор). Экология человека. 2022; (8): 531–46. https://doi.org/10.17816/humeco104609 https://elibrary.ru/osafti</mixed-citation><mixed-citation xml:lang="en">Nakhratova O.V., Tsygankova D.P., Bazdyrev E.D. Impact of air pollution with particulate particles on the risk of cardiovascular diseases (review). Ekologiya cheloveka. 2022; (8): 531–46. https://doi.org/10.17816/humeco104609 https://elibrary.ru/osafti (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Matsuzawa Y., Kwon T.G., Lennon R.J., Lerman L.O., Lerman A. Prognostic value of flow-mediated vasodilation in brachial artery and fingertip artery for cardiovascular events: a systematic review and meta-analysis. J. Am. Heart Assoc. 2015; 4(11): e002270. https://doi.org/10.1161/jaha.115.002270</mixed-citation><mixed-citation xml:lang="en">Matsuzawa Y., Kwon T.G., Lennon R.J., Lerman L.O., Lerman A. Prognostic value of flow-mediated vasodilation in brachial artery and fingertip artery for cardiovascular events: a systematic review and meta-analysis. J. Am. Heart Assoc. 2015; 4(11): e002270. https://doi.org/10.1161/jaha.115.002270</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Wang T., Shimizu Y., Wu X., Kelly G.T., Xu X., Wang L., et al. Particulate matter disrupts human lung endothelial cell barrier integrity via Rho-dependent pathways. Pulm. Circ. 2017; 7(3): 617–23. https://doi.org/10.1086/689906</mixed-citation><mixed-citation xml:lang="en">Wang T., Shimizu Y., Wu X., Kelly G.T., Xu X., Wang L., et al. Particulate matter disrupts human lung endothelial cell barrier integrity via Rho-dependent pathways. Pulm. Circ. 2017; 7(3): 617–23. https://doi.org/10.1086/689906</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Karki P., Meliton A., Shah A., Tian Y., Ohmura T., Sarich N., et al. Role of truncated oxidized phospholipids in acute endothelial barrier dysfunction caused by particulate matter. PLoS One. 2018; 13(11): e0206251. https://doi.org/10.1371/journal.pone.0206251</mixed-citation><mixed-citation xml:lang="en">Karki P., Meliton A., Shah A., Tian Y., Ohmura T., Sarich N., et al. Role of truncated oxidized phospholipids in acute endothelial barrier dysfunction caused by particulate matter. PLoS One. 2018; 13(11): e0206251. https://doi.org/10.1371/journal.pone.0206251</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Cserbik D., Chen J.C., McConnell R., Berhane K., Sowell E.R., Schwartz J., et al. Fine particulate matter exposure during childhood relates to hemispheric-specific differences in brain structure. Environ. Int. 2020; 143: 105933. https://doi.org/10.1016/j.envint.2020.105933</mixed-citation><mixed-citation xml:lang="en">Cserbik D., Chen J.C., McConnell R., Berhane K., Sowell E.R., Schwartz J., et al. Fine particulate matter exposure during childhood relates to hemispheric-specific differences in brain structure. Environ. Int. 2020; 143: 105933. https://doi.org/10.1016/j.envint.2020.105933</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Porta D., Narduzzi S., Badaloni C., Bucci S., Cesaroni G., Colelli V., et al. Air pollution and cognitive development at age 7 in a prospective Italian birth cohort. Epidemiology. 2016; 27(2): 228–36. https://doi.org/10.1097/ede.0000000000000405</mixed-citation><mixed-citation xml:lang="en">Porta D., Narduzzi S., Badaloni C., Bucci S., Cesaroni G., Colelli V., et al. Air pollution and cognitive development at age 7 in a prospective Italian birth cohort. Epidemiology. 2016; 27(2): 228–36. https://doi.org/10.1097/ede.0000000000000405</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Медик В.А., Токмачев М.С. Руководство по статистике здоровья и здравоохранения. М.: Медицина; 2006.</mixed-citation><mixed-citation xml:lang="en">Medik V.A., Tokmachev M.S. Guide to Health and Health Statistics [Rukovodstvo po statistike zdorov’ya i zdravookhraneniya]. Moscow: Meditsina; 2006. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Шишкин Г.С., Устюжанинова Н.В., Гультяева В.В. Функциональная организация системы внешнего дыхания при физической нагрузке. Бюллетень Сибирского отделения Российской академии медицинских наук. 2012; 32(6): 69–76. https://elibrary.ru/pncsnx</mixed-citation><mixed-citation xml:lang="en">Shishkin G.S., Ustyuzhaninova N.V., Gul’tyaeva V.V. Functional organization of respiratory system during physical activity. Byulleten’ Sibirskogo otdeleniya Rossiyskoy akademii meditsinskikh nauk. 2012; 32(6): 69–76. https://elibrary.ru/pncsnx (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Bralewska K., Rogula-Kozłowska W., Bralewski A. Size-segregated particulate matter in a selected sports facility in Poland. Sustainability. 2019; 11(24): 6911. https://doi.org/10.3390/su11246911</mixed-citation><mixed-citation xml:lang="en">Bralewska K., Rogula-Kozłowska W., Bralewski A. Size-segregated particulate matter in a selected sports facility in Poland. Sustainability. 2019; 11(24): 6911. https://doi.org/10.3390/su11246911</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Pinsky M.R. Cardiopulmonary interactions: physiologic basis and clinical applications. Ann. Am. Thorac. Soc. 2018; 15(Suppl. 1): S45–8. https://doi.org/10.1513/annalsats.201704-339fr</mixed-citation><mixed-citation xml:lang="en">Pinsky M.R. Cardiopulmonary interactions: physiologic basis and clinical applications. Ann. Am. Thorac. Soc. 2018; 15(Suppl. 1): S45–8. https://doi.org/10.1513/annalsats.201704-339fr</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Jaenisch R.B., Quagliotto E., Chechi C., Calegari L., Dos Santos F., Borghi-Silva A., et al. Respiratory muscle training improves chemoreflex response, heart rate variability, and respiratory mechanics in rats with heart failure. Can. J. Cardiol. 2017; 33(4): 508–14. https://doi.org/10.1016/j.cjca.2016.11.004</mixed-citation><mixed-citation xml:lang="en">Jaenisch R.B., Quagliotto E., Chechi C., Calegari L., Dos Santos F., Borghi-Silva A., et al. Respiratory muscle training improves chemoreflex response, heart rate variability, and respiratory mechanics in rats with heart failure. Can. J. Cardiol. 2017; 33(4): 508–14. https://doi.org/10.1016/j.cjca.2016.11.004</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Moreno A.M., Toledo-Arruda A.C., Lima J.S., Duarte C.S., Villacorta H., Nóbrega A.C. Inspiratory muscle training improves intercostal and forearm muscle oxygenation in patients with chronic heart failure: evidence of the origin of the respiratory metaboreflex. J. Card. Fail. 2017; 23(9): 672–9. https://doi.org/10.1016/j.cardfail.2017.05.003</mixed-citation><mixed-citation xml:lang="en">Moreno A.M., Toledo-Arruda A.C., Lima J.S., Duarte C.S., Villacorta H., Nóbrega A.C. Inspiratory muscle training improves intercostal and forearm muscle oxygenation in patients with chronic heart failure: evidence of the origin of the respiratory metaboreflex. J. Card. Fail. 2017; 23(9): 672–9. https://doi.org/10.1016/j.cardfail.2017.05.003</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
