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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medlit</journal-id><journal-title-group><journal-title xml:lang="ru">Гигиена и санитария</journal-title><trans-title-group xml:lang="en"><trans-title>Hygiene and Sanitation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0016-9900</issn><issn pub-type="epub">2412-0650</issn><publisher><publisher-name>Federal Scientific Center of Hygiene named after F.F. Erisman</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47470/0016-9900-2023-102-10-1029-1034</article-id><article-id custom-type="edn" pub-id-type="custom">ciycok</article-id><article-id custom-type="elpub" pub-id-type="custom">medlit-3476</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГИГИЕНА ОКРУЖАЮЩЕЙ СРЕДЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ENVIRONMENTAL HYGIENE</subject></subj-group></article-categories><title-group><article-title>Вопросы использования современных органических реагентов в практике питьевого водоснабжения (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Issues of using modern organic reagents in the practice of drinking water supply (literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0422-8382</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>Анна Венидиктовна</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseeva</surname><given-names>Anna V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, начальник отдела гигиены, ФГБУ «ЦСП» ФМБА России, 119121, г. Москва, ул. Погодинская, д. 10, стр. 1, Россия</p><p>e-mail: AAlekseeva@cspmz.ru</p></bio><bio xml:lang="en"><p>MD, PhD, Head of the Hygiene Department of the Centre for Strategic Planning of FMBA of Russia, Moscow, 119121, Russian Federation.</p><p>e-mail: AAlekseeva@cspmz.ru </p></bio><email xlink:type="simple">AAlekseeva@cspmz.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7032-1366</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Савостикова</surname><given-names>Ольга Николаевна</given-names></name><name name-style="western" xml:lang="en"><surname>Savostikova</surname><given-names>Olga N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, начальник отдела физико-химических методов исследования и экотоксикологии, ФГБУ «ЦСП» ФМБА России, 119121, г. Москва, ул. Погодинская, д. 10, стр. 1, Россия</p><p>e-mail: OSavostikova@cspmz.ru</p></bio><email xlink:type="simple">OSavostikova@cspmz.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Центр стратегического планирования и управления медико-биологическими рисками здоровью» Федерального медико-биологического агентства</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Centre for Strategic Planning and Management of Biomedical Health Risks of the FMBA</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>24</day><month>11</month><year>2023</year></pub-date><volume>102</volume><issue>10</issue><fpage>1029</fpage><lpage>1034</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Алексеева А.В., Савостикова О.Н., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Алексеева А.В., Савостикова О.Н.</copyright-holder><copyright-holder xml:lang="en">Alekseeva A.V., Savostikova O.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rjhas.ru/jour/article/view/3476">https://www.rjhas.ru/jour/article/view/3476</self-uri><abstract><p>Статья содержит обзор литературы, посвящённой безопасному использованию современных органических реагентов в практике питьевого водоснабжения. При проведении поиска литературы использовали следующие базы данных: Pubmed, Scopus, Web of Science, MedLine, Global Health, РИНЦ, а также метод поиска на основе ключевых слов и цитирования.</p><p>Цель обзора определялась актуальностью задачи удаления антропогенных и вызванных антропогенной нагрузкой загрязняющих веществ при очистке природных вод. Несмотря на большое число разработанных технологий и различных реагентов, эта задача не до конца решена. Технологии очистки воды совершенствуются, их эффективность в немалой степени зависит от интенсификации реагентной обработки. Помимо общепринятых лабораторных исследований реагентов, используемых при водоочистке, необходимо проведение производственных испытаний для уточнения параметров риска для здоровья и токсичности образующихся в процессе водоподготовки продуктов трансформации, а также для изучения эффективности и безопасности суммы реагентов, совместно поступающих в технологический процесс водоподготовки. Гигиеническая оценка реагентов должна учитывать реальные условия их использования в практике питьевого водоснабжения, включая дальнейшие стадии водоподготовки. Это касается оценки возможной деструкции полимеров при получении композитных реагентов, оценки модифицирующих добавок, входящих в их состав, трансформации полимеров в воде в процессе хлорирования, хлораминирования, озонирования, под влиянием ультрафиолетового облучения и корректировки набора обязательных контролируемых показателей. Для проведения этих исследований лаборатории должны обладать общедоступными методами анализа, позволяющими точно определить наличие мономеров, полимеров, а также различных добавок и продуктов трансформации в концентрациях, реально присутствующих в питьевой воде.</p><sec><title>Участие авторов</title><p>Участие авторов:Алексеева А.В. — концепция и дизайн исследования, написание текста, сбор материала и обработка данных, редактирование, утверждение окончательного варианта статьи, ответственность за целостность всех частей статьи;Савостикова О.Н. — концепция и дизайн исследования, написание текста, сбор материала и обработка данных, редактирование, утверждение окончательного варианта статьи, ответственность за целостность всех частей статьи.</p></sec><sec><title>Конфликт интересов</title><p>Конфликт интересов. Авторы декларируют отсутствие явных и потенциальных конфликтов интересов в связи с публикацией данной статьи.</p></sec><sec><title>Финансирование</title><p>Финансирование. Исследования проводились в рамках государственного задания по теме «Мониторинг» в ФГБУ «ЦСП» ФМБА России.</p></sec><sec><title>Поступила</title><p>Поступила: 28.08.2023 / Принята к печати: 26.09.2023 / Опубликована: 20.11.2023</p></sec></abstract><trans-abstract xml:lang="en"><p>The article contains a literature review devoted to the safe use of modern organic reagents in drinking water supply practice. When conducting a literature search, the following databases were used as follows: Pubmed, Scopus, Web of Science, MedLine, Global Health, RSCI, as well as a search method based on keywords and citations. The purpose of the review is that despite the large number of developed technologies and various reagents, the problem of removing anthropogenic and anthropogenic pollutants from natural water purification cannot be considered to be solved. Water purification technologies are being improved; their effectiveness largely depends on the intensification of reagent treatment.</p><p>In addition to generally accepted laboratory studies of the reagents used in water treatment, it is necessary to conduct production tests to clarify the parameters of the health risk and toxicity of the transformation products formed during the water treatment process, as well as to study the effectiveness and safety of a set of reagents that together enter the water treatment process. The hygienic assessment of reagents should take into account the actual conditions of their use in drinking water supply practice, including further stages of water treatment. This concerns the assessment of the possible destruction of polymers during the production of composite reagents, the assessment of modifying additives included in their composition, the transformation of polymers in water during chlorination, chloramination, ozonation, under the influence of ultraviolet irradiation, and adjustment of a set of mandatory controlled indicators. To conduct these studies, laboratories must have publicly available analytical methods that allow accurately determining the presence of monomers, polymers, as well as various additives and transformation products in concentrations actually present in drinking water.</p><sec><title>Contribution</title><p>Contribution:Alekseeva A.V. – the concept and design of the study, writing the text, collecting material and processing data, editing;Savostikova O.N. – concept and design of the study, writing the text, collecting material and processing data, editing.All authors are responsible for the integrity of all parts of the manuscript and approval of the manuscript final version.</p></sec><sec><title>Conflict of interest</title><p>Conflict of interest. The authors declare no conflict of interest.</p></sec><sec><title>Acknowledgement</title><p>Acknowledgement. The study had no sponsorship.</p></sec><sec><title>Received</title><p>Received: August 28, 2023 / Accepted: September 26, 2023 / Published: November 20, 2023</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>водоснабжение</kwd><kwd>реагенты для питьевого водоснабжения</kwd><kwd>синтетические полиэлектролиты</kwd><kwd>коагулянты</kwd><kwd>флокулянты</kwd><kwd>обзор</kwd></kwd-group><kwd-group xml:lang="en"><kwd>water supply</kwd><kwd>reagents for drinking water supply</kwd><kwd>synthetic polyelectrolytes</kwd><kwd>coagulants</kwd><kwd>flocculants</kwd><kwd>review</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ouyang W., Chen T., Shi Y., Tong L., Chen Y., Wang W., et al. Physico-chemical processes. Water Environ. Res. 2019; 91(10): 1350–77. https://doi.org/10.1002/wer.1231</mixed-citation><mixed-citation xml:lang="en">Ouyang W., Chen T., Shi Y., Tong L., Chen Y., Wang W., et al. Physico-chemical processes. Water Environ. Res. 2019; 91(10): 1350–77. https://doi.org/10.1002/wer.1231</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Xue J., Guo B., Gong Z. Physico-chemical processes. Water Environ. Res. 2018; 90(10): 1392–438. https://doi.org/10.2175/106143018X15289915807263</mixed-citation><mixed-citation xml:lang="en">Xue J., Guo B., Gong Z. Physico-chemical processes. Water Environ. Res. 2018; 90(10): 1392–438. https://doi.org/10.2175/106143018X15289915807263</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Вейцер Ю.И., Минц Д.М. Высокомолекулярные флокулянты в процессах очистки природных и сточных вод. М.: Стройиздат; 1984.</mixed-citation><mixed-citation xml:lang="en">Veytser Yu.I., Mints D.M. High-Molecular Flocculants in the Processes of Natural and Wastewater Treatment [Vysokomolekulyarnye flokulyanty v protsessakh ochistki prirodnykh i stochnykh vod]. Moscow: Stroyizdat; 1984. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Запольский А.К., Баран А.А. Коагулянты и флокулянты в процессах очистки воды: Свойства. Получение. Применение. М.: Химия; 1987.</mixed-citation><mixed-citation xml:lang="en">Zapol’skiy A.K., Baran A.A. Coagulants and Flocculants in Water Purification Processes: Properties. Receiving. Application [Koagulyanty i flokulyanty v protsessakh ochistki vody: Svoystva. Poluchenie. Primenenie]. Moscow: Khimiya; 1987. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Yu X., Tang Y., Pan J., Shen L., Begum A., Gong Z., et al. Physico-chemical processes. Water Environ. Res. 2020; 92(10): 1751–69. https://doi.org/10.1002/wer.1430</mixed-citation><mixed-citation xml:lang="en">Yu X., Tang Y., Pan J., Shen L., Begum A., Gong Z., et al. Physico-chemical processes. Water Environ. Res. 2020; 92(10): 1751–69. https://doi.org/10.1002/wer.1430</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Mishra S., Mukul A., Sen G., Jha U. Microwave assisted synthesis of polyacrylamide grafted starch (St-g-PAM) and its applicability as flocculant for water treatment. Int. J. Biol. Macromol. 2011; 48(1): 106–11. https://doi.org/10.1016/j.ijbiomac.2010.10.004</mixed-citation><mixed-citation xml:lang="en">Mishra S., Mukul A., Sen G., Jha U. Microwave assisted synthesis of polyacrylamide grafted starch (St-g-PAM) and its applicability as flocculant for water treatment. Int. J. Biol. Macromol. 2011; 48(1): 106–11. https://doi.org/10.1016/j.ijbiomac.2010.10.004</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Chen J., Eraghi Kazzaz A., AlipoorMazandarani N., Hosseinpour Feizi Z., Fatehi P. Production of flocculants, adsorbents, and dispersants from lignin. Molecules. 2018; 23(4): 868. https://doi.org/10.3390/molecules23040868</mixed-citation><mixed-citation xml:lang="en">Chen J., Eraghi Kazzaz A., AlipoorMazandarani N., Hosseinpour Feizi Z., Fatehi P. Production of flocculants, adsorbents, and dispersants from lignin. Molecules. 2018; 23(4): 868. https://doi.org/10.3390/molecules23040868</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Rajala K., Grönfors O., Hesampour M., Mikola A. Removal of microplastics from secondary wastewater treatment plant effluent by coagulation/flocculation with iron, aluminum and polyamine-based chemicals. Water Res. 2020; 183: 116045. https://doi.org/10.1016/j.watres.2020.116045</mixed-citation><mixed-citation xml:lang="en">Rajala K., Grönfors O., Hesampour M., Mikola A. Removal of microplastics from secondary wastewater treatment plant effluent by coagulation/flocculation with iron, aluminum and polyamine-based chemicals. Water Res. 2020; 183: 116045. https://doi.org/10.1016/j.watres.2020.116045</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Zheng C., Zheng H., Wang Y., Sun Y., An Y., Liu H., et al. Modified magnetic chitosan microparticles as novel superior adsorbents with huge “force field” for capturing food dyes. J. Hazard. Mater. 2019; 367: 492–503. https://doi.org/10.1016/j.jhazmat.2018.12.120</mixed-citation><mixed-citation xml:lang="en">Zheng C., Zheng H., Wang Y., Sun Y., An Y., Liu H., et al. Modified magnetic chitosan microparticles as novel superior adsorbents with huge “force field” for capturing food dyes. J. Hazard. Mater. 2019; 367: 492–503. https://doi.org/10.1016/j.jhazmat.2018.12.120</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Can İ.B., Bıçak Ö., Özçelik S., Can M., Ekmekçi Z. Sulphate removal from flotation process water using ion-exchange resin column system. Minerals. 2020; 10(8): 655. https://doi.org/10.3390/min10080655</mixed-citation><mixed-citation xml:lang="en">Can İ.B., Bıçak Ö., Özçelik S., Can M., Ekmekçi Z. Sulphate removal from flotation process water using ion-exchange resin column system. Minerals. 2020; 10(8): 655. https://doi.org/10.3390/min10080655</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Wang Q., Cao Y., Zeng H., Liang Y., Ma J., Lu X. Ultrasound-enhanced zero-valent copper activation of persulfate for the degradation of bisphenol AF. Chem. Eng. J. 2019; 378: 122143. https://doi.org/10.1016/j.cej.2019.122143</mixed-citation><mixed-citation xml:lang="en">Wang Q., Cao Y., Zeng H., Liang Y., Ma J., Lu X. Ultrasound-enhanced zero-valent copper activation of persulfate for the degradation of bisphenol AF. Chem. Eng. J. 2019; 378: 122143. https://doi.org/10.1016/j.cej.2019.122143</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Lin Z., Wang Y., Huang W., Wang J., Chen L., Zhou J., et al. Single-stage denitrifying phosphorus removal biofilter utilizing intracellular carbon source for advanced nutrient removal and phosphorus recovery. Bioresour. Technol. 2019; 277: 27–36. https://doi.org/10.1016/j.biortech.2019.01.025</mixed-citation><mixed-citation xml:lang="en">Lin Z., Wang Y., Huang W., Wang J., Chen L., Zhou J., et al. Single-stage denitrifying phosphorus removal biofilter utilizing intracellular carbon source for advanced nutrient removal and phosphorus recovery. Bioresour. Technol. 2019; 277: 27–36. https://doi.org/10.1016/j.biortech.2019.01.025</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Fu W., Zhang W. Microwave-enhanced membrane filtration for water treatment. J. Memb. Sci. 2018; 568: 97–104. https://doi.org/10.1016/j.memsci.2018.09.064</mixed-citation><mixed-citation xml:lang="en">Fu W., Zhang W. Microwave-enhanced membrane filtration for water treatment. J. Memb. Sci. 2018; 568: 97–104. https://doi.org/10.1016/j.memsci.2018.09.064</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Salehizadeh H., Yan N., Farnood R. Recent advances in polysaccharide bio-based flocculants. Biotech. Adv. 2018; 36(1): 92–119. https://doi.org/10.1016/j.biotechadv.2017.10.002</mixed-citation><mixed-citation xml:lang="en">Salehizadeh H., Yan N., Farnood R. Recent advances in polysaccharide bio-based flocculants. Biotech. Adv. 2018; 36(1): 92–119. https://doi.org/10.1016/j.biotechadv.2017.10.002</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Самбурский Г.А., Устинова О.В., Леонтьева С.В. Особенности стандартизации химических реагентов для подготовки питьевой воды (на примере коагулянта полиоксихлорида алюминия). Водоснабжение и санитарная техника. 2020; (1): 15–21. https://doi.org/10.35776/MNP.2020.01.02 https://elibrary.ru/kophvn</mixed-citation><mixed-citation xml:lang="en">Samburskiy G.A., Ustinova O.V., Leont’eva S.V. Specific features of standardization of chemicals for the preparation of drinking water (through the example of polyaluminium chloride coagulant). Vodosnabzhenie i sanitarnaya tekhnika. 2020; (1): 15–21. https://doi.org/10.35776/MNP.2020.01.02 https://elibrary.ru/kophvn (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Koshani R., Tavakolian M., van de Ven T.G.M. Cellulose-based dispersants and flocculants. J. Mater. Chem. B. 2020; 8(46): 10502–26. https://doi.org/10.1039/d0tb02021d</mixed-citation><mixed-citation xml:lang="en">Koshani R., Tavakolian M., van de Ven T.G.M. Cellulose-based dispersants and flocculants. J. Mater. Chem. B. 2020; 8(46): 10502–26. https://doi.org/10.1039/d0tb02021d</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Xu M., Wang X., Zhou B., Zhou L. Pre-coagulation with cationic flocculant-composited titanium xerogel coagulant for alleviating subsequent ultrafiltration membrane fouling by algae-related pollutants. J. Hazard. Mater. 2021; 407: 124838. https://doi.org/10.1016/j.jhazmat.2020.124838</mixed-citation><mixed-citation xml:lang="en">Xu M., Wang X., Zhou B., Zhou L. Pre-coagulation with cationic flocculant-composited titanium xerogel coagulant for alleviating subsequent ultrafiltration membrane fouling by algae-related pollutants. J. Hazard. Mater. 2021; 407: 124838. https://doi.org/10.1016/j.jhazmat.2020.124838</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang P., Zhu S., Xiong C., Yan B., Wang Z., Li K., et al. Flocculation of Chlorella vulgaris-induced algal blooms: critical conditions and mechanisms. Environ. Sci. Pollut. Res. Int. 2022; 29(52): 78809–20. https://doi.org/10.1007/s11356-022-21383-8</mixed-citation><mixed-citation xml:lang="en">Zhang P., Zhu S., Xiong C., Yan B., Wang Z., Li K., et al. Flocculation of Chlorella vulgaris-induced algal blooms: critical conditions and mechanisms. Environ. Sci. Pollut. Res. Int. 2022; 29(52): 78809–20. https://doi.org/10.1007/s11356-022-21383-8</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Wang Y., Gao B., Yue Q., Zhan X., Si X., Li C. Flocculation performance of epichlorohydrin-dimethylamine polyamine in treating dyeing wastewater. J. Environ. Manage. 2009; 91(2): 423–31. https://doi.org/10.1016/j.jenvman.2009.09.012</mixed-citation><mixed-citation xml:lang="en">Wang Y., Gao B., Yue Q., Zhan X., Si X., Li C. Flocculation performance of epichlorohydrin-dimethylamine polyamine in treating dyeing wastewater. J. Environ. Manage. 2009; 91(2): 423–31. https://doi.org/10.1016/j.jenvman.2009.09.012</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Zhu G., Liu J., Bian Y. Evaluation of cationic polyacrylamide-based hybrid coagulation for the removal of dissolved organic nitrogen. Environ. Sci. Pollut. Res. Int. 2018; 25(15): 14447–59. https://doi.org/10.1007/s11356-018-1630-1</mixed-citation><mixed-citation xml:lang="en">Zhu G., Liu J., Bian Y. Evaluation of cationic polyacrylamide-based hybrid coagulation for the removal of dissolved organic nitrogen. Environ. Sci. Pollut. Res. Int. 2018; 25(15): 14447–59. https://doi.org/10.1007/s11356-018-1630-1</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Liao Y., Zheng H., Dai L., Li F., Zhu G., Qingqing G., et al. Hydrophobically modified polyacrylamide synthesis and application in water treatment. Asian J. Chem. 2014; 26(18): 5923–7. https://doi.org/10.14233/ajchem.2014.16860</mixed-citation><mixed-citation xml:lang="en">Liao Y., Zheng H., Dai L., Li F., Zhu G., Qingqing G., et al. Hydrophobically modified polyacrylamide synthesis and application in water treatment. Asian J. Chem. 2014; 26(18): 5923–7. https://doi.org/10.14233/ajchem.2014.16860</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Chen X., Si C., Fatehi P. Cationic xylan-(2-methacryloyloxyethyl trimethyl ammonium chloride) polymer as a flocculant for pulping wastewater. Carbohydr. Polym. 2018; 186: 358–66. https://doi.org/10.1016/j.carbpol.2018.01.068</mixed-citation><mixed-citation xml:lang="en">Chen X., Si C., Fatehi P. Cationic xylan-(2-methacryloyloxyethyl trimethyl ammonium chloride) polymer as a flocculant for pulping wastewater. Carbohydr. Polym. 2018; 186: 358–66. https://doi.org/10.1016/j.carbpol.2018.01.068</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Lu L., Pan Z., Hao N., Peng W. A novel acrylamide-free flocculant and its application for sludge dewatering. Water Res. 2014; 57: 304–12. https://doi.org/10.1016/j.watres.2014.03.047</mixed-citation><mixed-citation xml:lang="en">Lu L., Pan Z., Hao N., Peng W. A novel acrylamide-free flocculant and its application for sludge dewatering. Water Res. 2014; 57: 304–12. https://doi.org/10.1016/j.watres.2014.03.047</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Жолдакова З.И., Синицына О.О., Тульская Е.А. Оценка санитарно-эпидемиологической безопасности флокулянтов, используемых для очистки питьевой воды. Гигиена и санитария. 2006; 85(5): 42–4. https://elibrary.ru/kuzlbr</mixed-citation><mixed-citation xml:lang="en">Zholdakova Z.I., Sinitsyna O.O., Tul’skaya E.A. Evaluation of the sanitary-and-epidemiological safety of flocculating agents used for portable water purification. Gigiena i Sanitaria (Hygiene and Sanitation, Russian journal). 2006; 85(5): 42–4. https://elibrary.ru/kuzlbr (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Алексеева А.В., Савостикова О.Н., Мамонов Р.А. Сравнительный анализ методов оценки возможности применения полимерных материалов в питьевом водоснабжении, закрепленных в законодательствах России и Германии. Международный журнал прикладных и фундаментальных исследований. 2019; (10–2): 263–7. https://elibrary.ru/uyvsgo</mixed-citation><mixed-citation xml:lang="en">Alekseeva A.V., Savostikova O.N., Mamonov R.A. Methodical issues of assessment of possibility of application in drinking water supply of polymeric materials. Mezhdunarodnyy zhurnal prikladnykh i fundamental’nykh issledovaniy. 2019; (10–2): 263–7. https://elibrary.ru/uyvsgo (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Liu Y., Zheng H., Sun Y., Ren J., Zheng X., Sun Q., et al. Synthesis of novel chitosan-based flocculants with amphiphilic structure and its application in sludge dewatering: role of hydrophobic groups. J. Clean. Prod. 2020; 249: 119350. https://doi.org/10.1016/j.jclepro.2019.119350</mixed-citation><mixed-citation xml:lang="en">Liu Y., Zheng H., Sun Y., Ren J., Zheng X., Sun Q., et al. Synthesis of novel chitosan-based flocculants with amphiphilic structure and its application in sludge dewatering: role of hydrophobic groups. J. Clean. Prod. 2020; 249: 119350. https://doi.org/10.1016/j.jclepro.2019.119350</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Jiang X., Li Y., Tang X., Jiang J., He Q., Xiong Z., et al. Biopolymer-based flocculants: a review of recent technologies. Environ. Sci. Pollut. Res. Int. 2021; 28(34): 46934–63. https://doi.org/10.1007/s11356-021-15299-y</mixed-citation><mixed-citation xml:lang="en">Jiang X., Li Y., Tang X., Jiang J., He Q., Xiong Z., et al. Biopolymer-based flocculants: a review of recent technologies. Environ. Sci. Pollut. Res. Int. 2021; 28(34): 46934–63. https://doi.org/10.1007/s11356-021-15299-y</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Bhalkaran S., Wilson L.D. Investigation of self-assembly processes for chitosan-based coagulant-flocculant systems: a mini-review. Int. J. Mol. Sci. 2016; 17(10): 1662. https://doi.org/10.3390/ijms17101662</mixed-citation><mixed-citation xml:lang="en">Bhalkaran S., Wilson L.D. Investigation of self-assembly processes for chitosan-based coagulant-flocculant systems: a mini-review. Int. J. Mol. Sci. 2016; 17(10): 1662. https://doi.org/10.3390/ijms17101662</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Tang X., Jiang X., Zhang S., Zheng H., Tan X. Recent progress on graft polymerization of natural polymer flocculants: synthesis method, mechanism and characteristic. Mini Rev. Org. Chem. 2018; 15(3): 227–35. https://doi.org/10.2174/1570193X15666171213155054</mixed-citation><mixed-citation xml:lang="en">Tang X., Jiang X., Zhang S., Zheng H., Tan X. Recent progress on graft polymerization of natural polymer flocculants: synthesis method, mechanism and characteristic. Mini Rev. Org. Chem. 2018; 15(3): 227–35. https://doi.org/10.2174/1570193X15666171213155054</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Zheng C., Zheng H., Wang Y., Wang Y., Qu W., An Q., et al. Synthesis of novel modified magnetic chitosan particles and their adsorption performance toward Cr(VI). Bioresour. Technol. 2018; 267: 1–8. https://doi.org/10.1016/j.biortech.2018.06.113</mixed-citation><mixed-citation xml:lang="en">Zheng C., Zheng H., Wang Y., Wang Y., Qu W., An Q., et al. Synthesis of novel modified magnetic chitosan particles and their adsorption performance toward Cr(VI). Bioresour. Technol. 2018; 267: 1–8. https://doi.org/10.1016/j.biortech.2018.06.113</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Sanchez-Salvador J.L., Balea A., Monte M.C., Negro C., Blanco A. Chitosan grafted/cross-linked with biodegradable polymers: a review. Int. J. Biol. Macromol. 2021; 178: 325–43. https://doi.org/10.1016/j.ijbiomac.2021.02.200</mixed-citation><mixed-citation xml:lang="en">Sanchez-Salvador J.L., Balea A., Monte M.C., Negro C., Blanco A. Chitosan grafted/cross-linked with biodegradable polymers: a review. Int. J. Biol. Macromol. 2021; 178: 325–43. https://doi.org/10.1016/j.ijbiomac.2021.02.200</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Duan C., Meng X., Meng J., Khan M.I.H., Dai L., Khan A., et al. Chitosan as a preservative for fruits and vegetables: a review on chemistry and antimicrobial properties. J. Biores. Bioproducts. 2019; 4(1): 11–21. https://doi.org/10.21967/jbb.v4i1.189</mixed-citation><mixed-citation xml:lang="en">Duan C., Meng X., Meng J., Khan M.I.H., Dai L., Khan A., et al. Chitosan as a preservative for fruits and vegetables: a review on chemistry and antimicrobial properties. J. Biores. Bioproducts. 2019; 4(1): 11–21. https://doi.org/10.21967/jbb.v4i1.189</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Sanchez-Salvador J.L., Balea A., Monte M.C., Negro C., Blanco A. Chitosan grafted/cross-linked with biodegradable polymers: a review. Int. J. Biol. Macromolec. 2021; 178: 325–43. https://doi.org/10.1016/j.ijbiomac.2021.02.200</mixed-citation><mixed-citation xml:lang="en">Sanchez-Salvador J.L., Balea A., Monte M.C., Negro C., Blanco A. Chitosan grafted/cross-linked with biodegradable polymers: a review. Int. J. Biol. Macromolec. 2021; 178: 325–43. https://doi.org/10.1016/j.ijbiomac.2021.02.200</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Lapointe M., Barbeau B. Substituting polyacrylamide with an activated starch polymer during ballasted flocculation. J. Water Process Eng. 2019; 28: 129–34. https://doi.org/10.1016/j.jwpe.2019.01.011</mixed-citation><mixed-citation xml:lang="en">Lapointe M., Barbeau B. Substituting polyacrylamide with an activated starch polymer during ballasted flocculation. J. Water Process Eng. 2019; 28: 129–34. https://doi.org/10.1016/j.jwpe.2019.01.011</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Wei H., Ren J., Li A., Yang H. Sludge dewaterability of a starch-based flocculant and its combined usage with ferric chloride. Chem. Engineer. J. 2018; 349: 737–47. https://doi.org/10.1016/j.cej.2018.05.151</mixed-citation><mixed-citation xml:lang="en">Wei H., Ren J., Li A., Yang H. Sludge dewaterability of a starch-based flocculant and its combined usage with ferric chloride. Chem. Engineer. J. 2018; 349: 737–47. https://doi.org/10.1016/j.cej.2018.05.151</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">El Halal S.L.M., Kringel D.H., Zavareze E.R., Dias A.R.G. Methods for extracting cereal starches from different sources: a review. Stärke. 2019; 71(11–12): 1900128. https://doi.org/10.1002/star.201900128</mixed-citation><mixed-citation xml:lang="en">El Halal S.L.M., Kringel D.H., Zavareze E.R., Dias A.R.G. Methods for extracting cereal starches from different sources: a review. Stärke. 2019; 71(11–12): 1900128. https://doi.org/10.1002/star.201900128</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Roy D., Semsarilar M., Guthrie J.T., Perrier S. Cellulose modification by polymer grafting: a review. Chem. Soc. Rev. 2009; 38(7): 2046–64. https://doi.org/10.1039/b808639g</mixed-citation><mixed-citation xml:lang="en">Roy D., Semsarilar M., Guthrie J.T., Perrier S. Cellulose modification by polymer grafting: a review. Chem. Soc. Rev. 2009; 38(7): 2046–64. https://doi.org/10.1039/b808639g</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Morantes D., Munoz E., Kam D., Shoseyov O. Highly charged cellulose nanocrystals applied as a water treatment flocculant. Nanomaterials (Basel). 2019; 9(2): 272. https://doi.org/10.3390/nano9020272.</mixed-citation><mixed-citation xml:lang="en">Morantes D., Munoz E., Kam D., Shoseyov O. Highly charged cellulose nanocrystals applied as a water treatment flocculant. Nanomaterials (Basel). 2019; 9(2): 272. https://doi.org/10.3390/nano9020272.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Negro C., Martín A.B., Sanchez-Salvador J.L., Campano C., Fuente E., Monte M.C., et al. Nanocellulose and its potential use for sustainable industrial applications. Lat. Am. Appl. Res. Int. J. 2020; 50(2): 59–64. https://doi.org/10.52292/j.laar.2020.471</mixed-citation><mixed-citation xml:lang="en">Negro C., Martín A.B., Sanchez-Salvador J.L., Campano C., Fuente E., Monte M.C., et al. Nanocellulose and its potential use for sustainable industrial applications. Lat. Am. Appl. Res. Int. J. 2020; 50(2): 59–64. https://doi.org/10.52292/j.laar.2020.471</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Campano C., Lopez-Exposito P., Blanco A., Negro C., van de Ven T.G.M. Hairy cationic nanocrystalline cellulose as a novel flocculant of clay. J. Colloid Interface Sci. 2019; 545: 153–61. https://doi.org/10.1016/j.jcis.2019.02.097</mixed-citation><mixed-citation xml:lang="en">Campano C., Lopez-Exposito P., Blanco A., Negro C., van de Ven T.G.M. Hairy cationic nanocrystalline cellulose as a novel flocculant of clay. J. Colloid Interface Sci. 2019; 545: 153–61. https://doi.org/10.1016/j.jcis.2019.02.097</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Brenelli L.B., Mandelli F., Mercadante A.Z., Rocha G.J.M., Rocco S.A., Craievich A.F., et al. Acidification treatment of lignin from sugarcane bagasse results in fractions of reduced polydispersity and high free-radical scavenging capacity. Ind. Crop. Prod. 2016; 83: 94–103. https://doi.org/10.1016/j.indcrop.2015.12.013</mixed-citation><mixed-citation xml:lang="en">Brenelli L.B., Mandelli F., Mercadante A.Z., Rocha G.J.M., Rocco S.A., Craievich A.F., et al. Acidification treatment of lignin from sugarcane bagasse results in fractions of reduced polydispersity and high free-radical scavenging capacity. Ind. Crop. Prod. 2016; 83: 94–103. https://doi.org/10.1016/j.indcrop.2015.12.013</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Guo K., Gao B., Yue Q., Xu X., Li R., Shen X. Characterization and performance of a novel lignin-based flocculant for the treatment of dye wastewater. Int. Biodeterior. Biodegrad. 2018; 133: 99–107. https://doi.org/10.1016/j.ibiod.2018.06.015</mixed-citation><mixed-citation xml:lang="en">Guo K., Gao B., Yue Q., Xu X., Li R., Shen X. Characterization and performance of a novel lignin-based flocculant for the treatment of dye wastewater. Int. Biodeterior. Biodegrad. 2018; 133: 99–107. https://doi.org/10.1016/j.ibiod.2018.06.015</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Jiang Z., Hu C. Selective extraction and conversion of lignin in actual biomass to monophenols: a review. J. Energy Chem. 2016; 25(6): 947–56. https://doi.org/10.1016/j.jechem.2016.10.008</mixed-citation><mixed-citation xml:lang="en">Jiang Z., Hu C. Selective extraction and conversion of lignin in actual biomass to monophenols: a review. J. Energy Chem. 2016; 25(6): 947–56. https://doi.org/10.1016/j.jechem.2016.10.008</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Xia Z., Li J., Zhang J., Zhang X., Zheng X., Zhang J. Processing and valorization of cellulose, lignin and lignocellulose using ionic liquids. J. Biores. Bioprod. 2020; 5(2): 79–95. https://doi.org/10.1016/j.jobab.2020.04.001</mixed-citation><mixed-citation xml:lang="en">Xia Z., Li J., Zhang J., Zhang X., Zheng X., Zhang J. Processing and valorization of cellulose, lignin and lignocellulose using ionic liquids. J. Biores. Bioprod. 2020; 5(2): 79–95. https://doi.org/10.1016/j.jobab.2020.04.001</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Jiang X., Li Y., Tang X., Jiang J., He Q., Xiong Z., et al. Biopolymer-based flocculants: a review of recent technologies. Environ. Sci. Pollut. Res. Int. 2021; 28(34): 46934–63. https://doi.org/10.1007/s11356-021-15299-y</mixed-citation><mixed-citation xml:lang="en">Jiang X., Li Y., Tang X., Jiang J., He Q., Xiong Z., et al. Biopolymer-based flocculants: a review of recent technologies. Environ. Sci. Pollut. Res. Int. 2021; 28(34): 46934–63. https://doi.org/10.1007/s11356-021-15299-y</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Реестр аккредитованных лиц. Available at: https://pub.fsa.gov.ru/ral</mixed-citation><mixed-citation xml:lang="en">Register of accredited conformity assessment bodies. Available at: https://pub.fsa.gov.ru/ral</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Кремко Л., Саракач О., Докутович А. Определение акриламида в питьевой воде методом газожидкостной хроматографии. Наука и инновации. 2014; (9): 67–9. https://elibrary.ru/tbbkpn</mixed-citation><mixed-citation xml:lang="en">Kremko L., Sarakach O., Dokutovich A. The acrylamide rate in drinking water testing with the gas-liquid chromatography. Nauka i innovatsii. 2014; (9): 67–9. https://elibrary.ru/tbbkpn (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Лопушанская Е.М., Максакова И.Б., Крылов А.И. Определение акриламида в воде методом ВЭЖХ/МС для обеспечения контроля качества питьевой воды. Вода: химия и экология. 2017; (10): 62–7. https://elibrary.ru/yuujbg</mixed-citation><mixed-citation xml:lang="en">Lopushanskaya E.M., Maksakova I.B., Krylov A.I. Determination of acrylamide in water by HPLC/MS method for drinking water quality control. Voda: khimiya i ekologiya. 2017; (10): 62–7. https://elibrary.ru/yuujbg (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Letterman R.D., Pero R.W. Contaminants in polyelectrolytes used in water treatment. J. Am. Water Works Ass. 1990; 82(11): 87–97.</mixed-citation><mixed-citation xml:lang="en">Letterman R.D., Pero R.W. Contaminants in polyelectrolytes used in water treatment. J. Am. Water Works Ass. 1990; 82(11): 87–97.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Charrois J.W.A., Hrudey S.E. Breakpoint chlorination and free-chlorine contact time: Implications for drinking water N-nitrosodimethylamine concentrations. Water Res. 2007; 41(3): 674–82. https://doi.org/10.1016/j.watres.2006.07.031</mixed-citation><mixed-citation xml:lang="en">Charrois J.W.A., Hrudey S.E. Breakpoint chlorination and free-chlorine contact time: Implications for drinking water N-nitrosodimethylamine concentrations. Water Res. 2007; 41(3): 674–82. https://doi.org/10.1016/j.watres.2006.07.031</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Tan S., Jiang S., Lai Y., Yuan Q. Formation potential of nine nitrosamines from polyacrylamide during chloramination. Sci. Total. Environ. 2019; 670: 1103–10. https://doi.org/10.1016/j.scitotenv.2019.03.281</mixed-citation><mixed-citation xml:lang="en">Tan S., Jiang S., Lai Y., Yuan Q. Formation potential of nine nitrosamines from polyacrylamide during chloramination. Sci. Total. Environ. 2019; 670: 1103–10. https://doi.org/10.1016/j.scitotenv.2019.03.281</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Park S.H., Padhye L.P., Wang P., Cho M., Kim J.H., Huang C.H. N-nitrosodimethylamine (NDMA) formation potential of amine-based water treatment polymers: Effects of in situ chloramination, breakpoint chlorination, and pre-oxidation. J. Hazard. Mater. 2015; 282: 133–40. https://doi.org/10.1016/j.jhazmat.2014.07.044</mixed-citation><mixed-citation xml:lang="en">Park S.H., Padhye L.P., Wang P., Cho M., Kim J.H., Huang C.H. N-nitrosodimethylamine (NDMA) formation potential of amine-based water treatment polymers: Effects of in situ chloramination, breakpoint chlorination, and pre-oxidation. J. Hazard. Mater. 2015; 282: 133–40. https://doi.org/10.1016/j.jhazmat.2014.07.044</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Tan S., Jiang S., Li X., Yuan Q. Factors affecting N-nitrosodimethylamine formation from poly(diallyldimethyl-ammonium chloride) degradation during chloramination. R. Soc. Open Sci. 2018; 5(8): 180025. https://doi.org/10.1098/rsos.180025</mixed-citation><mixed-citation xml:lang="en">Tan S., Jiang S., Li X., Yuan Q. Factors affecting N-nitrosodimethylamine formation from poly(diallyldimethyl-ammonium chloride) degradation during chloramination. R. Soc. Open Sci. 2018; 5(8): 180025. https://doi.org/10.1098/rsos.180025</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Deng L., Huang C.H., Wang Y.L. Effects of combined UV and chlorine treatment on the formation of trichloronitromethane from amine precursors. Environ. Sci. Technol. 2014; 48(5): 2697–705. https://doi.org/10.1021/es404116n</mixed-citation><mixed-citation xml:lang="en">Deng L., Huang C.H., Wang Y.L. Effects of combined UV and chlorine treatment on the formation of trichloronitromethane from amine precursors. Environ. Sci. Technol. 2014; 48(5): 2697–705. https://doi.org/10.1021/es404116n</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Zeng T., Li R.J., Mitch W.A. Structural modifications to quaternary ammonium polymer coagulants to inhibit n-nitrosamine formation. Environ. Sci. Technol. 2016; 50(9): 4778–87. https://doi.org/10.1021/acs.est.6b00602</mixed-citation><mixed-citation xml:lang="en">Zeng T., Li R.J., Mitch W.A. Structural modifications to quaternary ammonium polymer coagulants to inhibit n-nitrosamine formation. Environ. Sci. Technol. 2016; 50(9): 4778–87. https://doi.org/10.1021/acs.est.6b00602</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Тафеева Е.А., Снигирев С.В., Аксенов Н.Г. Реагенты, используемые в практике хозяйственно-питьевого водоснабжения: проблемы безопасности. Вода: химия и экология. 2019; (7–9): 102–7. https://elibrary.ru/pdhvfo</mixed-citation><mixed-citation xml:lang="en">Tafeeva E.A., Snigirev S.V., Aksenov N.G. Reagents used in drinking water supply practice: safety problems. Voda: khimiya i ekologiya. 2019; (7–9): 102–7. https://elibrary.ru/pdhvfo (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Ma J., Wang R., Wang X., Zhang H., Zhu B., Lian L., et al. Drinking water treatment by stepwise flocculation using polysilicate aluminum magnesium and cationic polyacrylamide. J. Environ. Chem. Engineer. 2019; 7(3): 103049.</mixed-citation><mixed-citation xml:lang="en">Ma J., Wang R., Wang X., Zhang H., Zhu B., Lian L., et al. Drinking water treatment by stepwise flocculation using polysilicate aluminum magnesium and cationic polyacrylamide. J. Environ. Chem. Engineer. 2019; 7(3): 103049.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
