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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medlit</journal-id><journal-title-group><journal-title xml:lang="ru">Гигиена и санитария</journal-title><trans-title-group xml:lang="en"><trans-title>Hygiene and Sanitation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0016-9900</issn><issn pub-type="epub">2412-0650</issn><publisher><publisher-name>Federal Scientific Center of Hygiene named after F.F. Erisman</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47470/0016-9900-2019-98-7-761-765</article-id><article-id custom-type="elpub" pub-id-type="custom">medlit-368</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОЦЕНКА РИСКОВ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RISK ASSESSMENT</subject></subj-group></article-categories><title-group><article-title>Биологический возраст как метод оценки уровня здоровья при наличии экологических рисков (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Biological age as a method for estimating health level under environmental risks (literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4510-2890</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прохоров</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Prokhorov</surname><given-names>N. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2234-4715</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Донцов</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Dontsov</surname><given-names>V. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2779-8775</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крутько</surname><given-names>Вячеслав Николаевич</given-names></name><name name-style="western" xml:lang="en"><surname>Krutko</surname><given-names>Vyacheslav N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор техн. наук, проф., зав. отд. ФГБУ «ФИЦ «Информатика и управление» РАН, 119333, Москва.</p><p>e-mail: krutkovn@mail.ru</p></bio><bio xml:lang="en"><p>MD, Ph.D., Head of Laboratory, Federal Research Center “Computer Science and Control”, Moscow, 119333, Russian Federation.</p><p>e-mail: krutkovn@mail.ru</p></bio><email xlink:type="simple">krutkovn@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9646-5595</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ходыкина</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Khodykina</surname><given-names>T. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ Первый МГМУ им. И.М. Сеченова Минздрава России</institution></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «Федеральный исследовательский центр «Информатика и управление» Российской академии наук</institution></aff><aff xml:lang="en"><institution>Federal Research Center “Computer Science and Control”</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГАОУ Первый МГМУ им. И.М. Сеченова Минздрава России; ФГБУ «Федеральный исследовательский центр «Информатика и управление» Российской академии наук</institution></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University; Federal Research Center “Computer Science and Control”</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>14</day><month>10</month><year>2020</year></pub-date><volume>98</volume><issue>7</issue><fpage>761</fpage><lpage>765</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Прохоров Н.И., Донцов В.И., Крутько В.Н., Ходыкина Т.М., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Прохоров Н.И., Донцов В.И., Крутько В.Н., Ходыкина Т.М.</copyright-holder><copyright-holder xml:lang="en">Prokhorov N.I., Dontsov V.I., Krutko V.N., Khodykina T.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rjhas.ru/jour/article/view/368">https://www.rjhas.ru/jour/article/view/368</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>гигиенический мониторинг</kwd><kwd>здоровье</kwd><kwd>старение</kwd><kwd>биологический возраст</kwd><kwd>информационные технологии</kwd><kwd>диагностические компьютерные программы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hygienic monitoring</kwd><kwd>health</kwd><kwd>aging</kwd><kwd>biological age</kwd><kwd>information technology</kwd><kwd>diagnostic computer programs</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Зайцева Н.В., Уланова Т.С., Нурисламова Т.В., Попова Н.А., Мальцева О.А. Количественные показатели нитратов в моче и n-нитрозодиметиламина в крови как маркеры пероральной экспозиции нитратов, поступающих с питьевой водой. Гигиена и санитария. 2018; 97(11): 1087-92. https://doi.org/10.18821/0016-9900-2018-97-11-1087-92</mixed-citation><mixed-citation xml:lang="en">Zajceva N.V., Ulanova T.S., Nurislamova T.V., Popova N.A., Mal’ceva O.A. Quantitative indicators of nitrates in urine and n-nitrosodimethylamine in blood as markers of oral exposure of nitrates coming from drinking water. Gigiena i sanitariya [Hygiene and Sanitation, Russian journal]. 2018; 97(11): 1087-92. (in Russian). https://doi.org/10.18821/0016-9900-2018-97-11-1087-92</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Малов А.М., Луковникова Л.В., Аликбаева Л.А., Якубова И.Ш., Щеголихин Д.К. Результаты биомониторинга ртутного загрязнения территории мегаполиса. Гигиена и санитария. 2018; 97(12): 1189-94. https://doi.org/10.18821/0016-9900-2018-97-12-1189-1194</mixed-citation><mixed-citation xml:lang="en">Malov A.M., Lukovnikova L.V., Alikbaeva L.A., Jakubova I.Sh., Shhegolihin D.K. Results of biomonitoring of mercury pollution within the metropolis. Gigiena i sanitariya [Hygiene and Sanitation, Russian journal]. 2018; 97(12): 1189-94. (in Russian). https://doi.org/10.18821/0016-9900-2018-97-12-1189-1194</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Ященко С.Г., Рыбалко С.Ю., Шибанов С.Э., Григорьев О.А. Электромагнитная обстановка радиочастотного диапазона мобильной связи и заболеваемость взрослого населения болезнями системы кровообращения. Гигиена и санитария. 2018; 97(12): 1184-8. https://doi.org/10.18821/0016-9900-2018-97-12-1184-1188</mixed-citation><mixed-citation xml:lang="en">Jashhenko S.G., Rybalko S.Ju., Shibanov S.Je., Grigor’ev O.A. Electromagnetic environment of radio frequency range of mobile communication and morbidity of adult population with diseases of the circulatory system. Gigiena i sanitariya [Hygiene and Sanitation, Russian journal]. 2018; 97(12): 1184-8. (in Russian). https://doi.org/10.18821/0016-9900-2018-97-12-1184-1188</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Крийт В.Е., Сладкова Ю.Н., Смирнов В.В. Двухуровневые автомобильные мосты как особый источник шумового воздействия на жилую застройку на примере канонерского острова Санкт-Петербурга. Гигиена и санитария. 2018; 97(12): 1162-5. https://doi.org/10.18821/0016-9900-2018-97-12-1162-1165</mixed-citation><mixed-citation xml:lang="en">Krijt V.E., Sladkova Ju.N., Smirnov V.V.Hygiene and sanitation. Two-level road bridges as a special source of noise impact on residential development on the example of the Kanonersky island of St. Petersburg. Gigiena i sanitariya [Hygiene and Sanitation, Russian journal]. 2018; 97(12): 1162-5. (in Russian). https://doi.org/10.18821/0016-9900-2018-97-12-1162-1165</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Малышева А.Г., Шелепова О.В., Водянова М.А., Донерьян Л.Г., Ушакова О.В., Юдин С.М. Эколого-гигиенические проблемы применения противогололёдных реагентов в условиях крупного мегаполиса (на примере территории города Москвы). Гигиена и санитария. 2018; 97(11): 1032-7. https://doi.org/10.18821/0016-9900-2018-97-11-1032-37</mixed-citation><mixed-citation xml:lang="en">Malysheva A.G., Shelepova O.V., Vodjanova M.A., Doner’jan L.G., Ushakova O.V., Judin S.M. Ekologo-hygienic problems of application of antihydrogen reagents in the conditions of a large megapolis (on the example of the city of Moscow). Gigiena i sanitariya [Hygiene and Sanitation, Russian journal]. 2018; 97(11): 1032-7. (in Russian). https://doi.org/10.18821/0016-9900-2018-97-11-1032-37</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Салтыкова М.М., Бобровницкий И.П., Яковлев М.Ю., Банченко А.Д., Нагорнев С.Н. Новый подход к анализу влияния погодных условий на организм человека. Гигиена и санитария. 2018; 97(11): 1038-42. https://doi.org/10.18821/0016-9900-2018-97-11-1038-42</mixed-citation><mixed-citation xml:lang="en">Saltykova M.M., Bobrovnickij I.P., Jakovlev M.Ju., Banchenko A.D., Nagornev S.N. A new approach to the analysis of the influence of weather conditions on the human body. Gigiena i sanitariya [Hygiene and Sanitation, Russian journal]. 2018; 97(11): 1038-42. (in Russian). https://doi.org/10.18821/0016-9900-2018-97-11-1038-42</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Большаков А.М., Крутько В.Н., Кутепов Е.Н., Мамиконова О.А., Потемкина Н.С., Розенблит С.И. и др. Информационные нагрузки как новый актуальный раздел гигиены детей и подростков. Гигиена и санитария. 2016; 95(2): 172-7. https://doi.org/10.18821/0016-9900-2016-95-2-172-177</mixed-citation><mixed-citation xml:lang="en">Bol’shakov A.M., Krut’ko V.N., Kutepov E.N., Mamikonova O.A., Potemkina N.S., Rozenblit S.I. et al. Chunks of Information overload as a new topical section of hygiene of children and adolescents. Gigiena i sanitariya [Hygiene and Sanitation, Russian journal]. 2016; 95(2): 172-7. (in Russian). https://doi.org/10.18821/0016-9900-2016-95-2-172-177</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Ермакова Н.А., Мельниченко П.И., Прохоров Н.И., Тимошенко К.Т., Матвеев А.А., Кочина Е.В. и др. Образ жизни и здоровье студентов. Гигиена и санитария. 2016; 95(6): 558-63. https://doi.org/10.18821/0016-9900-2016-95-6-558-563</mixed-citation><mixed-citation xml:lang="en">Ermakova N.A., Mel’nichenko P.I., Prohorov N.I., Timoshenko K.T., Matveev A.A., Kochina E.V. et al. Lifestyle and health of students. Gigiena i sanitariya [Hygiene and Sanitation, Russian journal]. 2016; 95(6): 558-63. (in Russian). https://doi.org/10.18821/0016-9900-2016-95-6-558-563</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Смирнова Т.М., Крутько В.Н. Историческая динамика смертности и ее учет в целях стратегического планирования медицинской и социальной помощи пожилым. Клиническая геронтология. 2018; 24(9-10): 63-5.</mixed-citation><mixed-citation xml:lang="en">Smirnova T.M., Krut’ko V.N. Historical dynamics of mortality and its accounting for the strategic planning of medical and social care for the elderly. Klinicheskaja gerontologija. 2018; 24(9-10): 63-5. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Большаков А.М., Крутько В.Н., Смирнова Т.М., Чанков С.В. Метод ранговых индексов и его использование для сравнительного анализа гигиенического благополучия населения. Гигиена и санитария. 2016; 95(3): 306-11. https://doi.org/10.18821/00169900-2016-95-3-306-311</mixed-citation><mixed-citation xml:lang="en">Bol’shakov A.M., Krut’ko V.N., Smirnova T.M., Chankov S.V. Method of ranking indices and its use for comparative analysis of hygienic welfare of the population. Gigiena i sanitariya [Hygiene and Sanitation, Russian journal]. 2016: 95(3): 306-11. (in Russian). https://doi.org/10.18821/00169900-2016-95-3-306-311</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Власова И.А. Реакции неспецифической адаптации и функциональное состояние организма пожилых лиц. Сибир. мед. журнал. Иркутск: 2012; 113(6): 46-8.</mixed-citation><mixed-citation xml:lang="en">Vlasova I.A. Nonspecific Reactions of adaptation and functional state of the organism elderly. Sibirskiy meditsinskiy jurnal (Irkutsk). 2012; 113(6): 46-8. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Мельниченко П.И., Ермакова Н.А., Прохоров Н.И., Матвеев А.А., Кочина Е.В. Биологический возраст как оценка и критерий состояния здоровья студентов. Здоровье населения и среда обитания. 2017; 2(287): 15-7.</mixed-citation><mixed-citation xml:lang="en">Mel’nichenko P.I., Ermakova N.A., Prohorov N.I., Matveev A.A., Kochina E.V. Biological age as a rating criterion and the state of health of students. Zdorov’e naselenija i sreda obitanija. 2017; 2(287): 15-7. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Krutko V.N., Dontsov V.I., Mamikonova O.A., Markova A.M., Molodchenkov A.I., Potemkina N.S. et al. Intelligent internet technology for personalized health-saving support. Advances in Intelligent Systems and Computing. 2018; 658: 157-65. https://doi.org/10.1007/978-3-319-67349-3_14</mixed-citation><mixed-citation xml:lang="en">Krutko V.N., Dontsov V.I., Mamikonova O.A., Markova A.M., Molodchenkov A.I., Potemkina N.S. et al. Intelligent internet technology for personalized health-saving support. Advances in Intelligent Systems and Computing. 2018; 658: 157-65. https://doi.org/10.1007/978-3-319-67349-3_14</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Смирнова Т.М., Крутько В.Н., Маркова А.М. Анализ биовозраста с помощью компьютерного мониторинга работоспособности и психо-эмоционального состояния как элемент превентивно-персонализированного подхода к управлению здоровьем. Вестник восстановительной медицины. 2018; 1(83): 54-60.</mixed-citation><mixed-citation xml:lang="en">Smirnova T.M., Krut’ko V.N., Markova A.M. Analysis of biologocal age using a computer to monitor the health and psycho-emotional condition as an element of a preventive and personalized approach to health management. Vestnik vosstanovitel’noj mediciny. 2018; 1(83): 54-60. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Башкирёва А.С. Оценка ускоренного старения водителей автотранспорта на модели биологического возраста по показателям физической работоспособности. Успехи геронтологии. 2012; 25(4): 709-17.</mixed-citation><mixed-citation xml:lang="en">Bashkireva A.S. Assessment of accelerated aging truck drivers on the model of biological age on physical performance indicators. Uspekhi gerontologii. 2012; 25(4): 709-17. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Пучкова Е.И., Алишев Н.В. Показатели биологического возраста и ускоренное старение у ликвидаторов последствий радиационных аварий. Успехи геронтологии. 2011; 24(1): 99-104.</mixed-citation><mixed-citation xml:lang="en">Puchkova E.I., Alishev N.V. Indicators of biological age and ageing in liquidators of consequences of radiation accidents]. Uspeki gerontologii. 2011; 24(1): 99-104. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Черемушникова И.И., Давыдова Н.О., Гривко Н.В., Барышева Е.С. Мониторинг биологического возраста студентов как показатель адаптации в вузе. Врач-аспирант. 2012; 53(4): 285-292.</mixed-citation><mixed-citation xml:lang="en">Cheremisinova I.I., Davydov N.O., Grivko N.V., Barysheva Y.S. Monitoring of biological age of the students as an indicator of adaptation in University. Vrach-aspirant. 2012; 53(4): 285-92. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Большаков А.М., Крутько В.Н., Донцов В.И. Возможности компьютерных систем для оценки донозологических изменений здоровья. Гигиена и санитария. 2017; 96(11): 1115-8. https://doi.org/10.18821/0016-9900-2017-96-11-1115-1118</mixed-citation><mixed-citation xml:lang="en">Bol’shakov A.M., Krut’ko V.N., Dontsov V.I. Possibilities of computer systems for assessment of prenosological changes in health. Gigiena i sanitarija. 2017; 96(11): 1115-8. (in Russian). https://doi.org/10.18821/0016-9900-2017-96-11-1115-8</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Gary A., Borkan Arthur H., Norris G. Assessment of biological age using a profile of physical parameters. J. Gerontol. 1980; 35: 177-84</mixed-citation><mixed-citation xml:lang="en">Gary A., Borkan Arthur H., Norris G. Assessment of biological age using a profile of physical parameters. J. Gerontol. 1980; 35: 177-84.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Прохоров Н.И., Донцов В.И., Крутько В.Н., Ходыкина Т.М. Биологический возраст как метод оценки рисков изменений здоровья, обусловленных природно-климатическими и экологическими факторами. Анализ прогностической значимости экологического рейтинга регионов Российской Федерации. «Современные проблемы оценки, прогноза и управления экологическими рисками здоровью населения и окружающей среды, пути их рационального решения». Материалы III Международного форума Научного совета Российской Федерации по экологии человека и гигиене окружающей среды 13-14 декабря 2018 г. Москва, 2018: 294-7.</mixed-citation><mixed-citation xml:lang="en">Prohorov N.I., Dontsov V.I., Krut’ko V.N., Hodykina T.M. Biological age as a method of assessing the risks of health changes caused by natural, climatic and environmental factors. Analysis of the prognostic significance of the environmental rating of the Russian Federation regions. “Modern problems of assessment, forecasting and management of environmental risks to public health and the environment, ways of their rational solution”. Materials of the III international forum of the Scientific Council of the Russian Federation on human ecology and environmental hygiene 13-14 December 2018. [Materialy III Mezhdunarodnogo foruma Nauchnogo soveta Rossijskoj Federacii po jekologii cheloveka i gigiene okruzhajushhej sredy 13-14 dekabrja 2018]. Moscow; 2018: 294-7. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Крутько В.Н., Донцов В.И., Захарьящева О.В., Кузнецов И.А., Мамиконова О.А., Пырву В.В. и др. Биологический возраст как показатель уровня здоровья, старения и экологического благополучия человека. Авиакосмическая и экологическая медицина. 2014; 48 (3): 2-19.</mixed-citation><mixed-citation xml:lang="en">Krut’ko V.N., Dontsov V.I., Zahar’jashheva O.V., Kuznecov I.A., Mamikonova O.A., Pyrvu V.V. et al. Biological age as an indicator of the level of health, aging, and environmental well-being of the person. Aviakosmicheskaja i jekologicheskaja medicina. 2014; 48(3): 2-19. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Донцов В.И., Крутько В.Н. Старение: системный подход. Труды ИСА РАН. 2017; 67(1): 104-12.</mixed-citation><mixed-citation xml:lang="en">Dontsov V.I., Krut`ko V.N. Aging: a systematic approach. Trudy ISA RAN. 2017; 67(1): 104-12. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Karasik D., Demissie S., Cupples A., Kiel D. Disentangling the genetic determinants of human aging: biological age as an alternative to the use of survival measures. J. gerontol. A. Biol. Sci. Med. Sci. 2005; 60: 574-87</mixed-citation><mixed-citation xml:lang="en">Karasik D., Demissie S., Cupples A., Kiel D. Disentangling the genetic determinants of human aging: biological age as an alternative to the use of survival measures. J. gerontol. A. Biol. Sci. Med. Sci. 2005; 60: 574-87.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Донцов В.И., Крутько В.Н. «БИОВОЗРАСТ: количественная диагностика старения и рисков смерти». Свидетельство о государственной регистрации программы для ЭВМ № 2016663535; 2016.</mixed-citation><mixed-citation xml:lang="en">Dontsov V.I., Krut`ko V.N. Biological age : quantitative diagnosis of aging and risk of mortality. Certificate of state registration of computer programs № 2016663535 RF. 2016. (in Russian). https://doi.org/10.1093/geronb/gbr039</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Холин В.А., Бачинская Н.Ю., Безруков В.В. Нейрофункциональный биологический возраст у лиц пожилого возраста с синдромом умеренных когнитивных нарушений. Украинский неврологический журнал. 2007; 4 (5): 024-8.</mixed-citation><mixed-citation xml:lang="en">Holin V.A., Bachinskaya N.Yu., Bezrukov V.V. Neurofunctional biological age in the elderly with the syndrome of moderate cognitive impairment. Ukrainian neurological journal. 2007; 4 (5): 024-8. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">MacDonald S.W, DeCarlo C.A., Dixon R.A. Linking biological and cognitive aging: toward improving characterizations of developmental time. J Gerontol B Psychol Sci Soc Sci. 2011; 66(Suppl 1): i59-70. https://doi.org/10.1093/geronb/gbr039</mixed-citation><mixed-citation xml:lang="en">MacDonald S.W, DeCarlo C.A., Dixon R.A. Linking biological and cognitive aging: toward improving characterizations of developmental time. J Gerontol B Psychol Sci Soc Sci. 2011; 66(Suppl 1): i59-70. https://doi.org/10.1093/geronb/gbr039</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Dontsov V.I., Krutko V.N. Biological age as a method for systematic assessment of ontogenetic changes in the state of an organism. Russian Journal of Developmental Biology. 2015; 46(5): 246-53. https://doi.org/10.1134/S1062360415050033</mixed-citation><mixed-citation xml:lang="en">Dontsov V.I., Krutko V.N. Biological age as a method for systematic assessment of ontogenetic changes in the state of an organism. Russian Journal of Developmental Biology. 2015; 46(5): 246-53. https://doi.org/10.1134/S1062360415050033</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Sprott R.L. Biomarkers of aging and disease: Introduction and definitions. Exp. Gerontol. 2010; 45: 2-4. https://doi.org/10.1016/j.exger.2009.07.008</mixed-citation><mixed-citation xml:lang="en">Sprott R.L. Biomarkers of aging and disease: Introduction and definitions. Exp. Gerontol. 2010; 45: 2-4. https://doi.org/10.1016/j.exger.2009.07.008</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Плакуева А.Н., Хромова А.В., Катышева Л.В., Попов Д.С. Биологический возраст у молодых людей, проживающих в условиях европейского севера. Экология человека. 2006; 11: 17-20.</mixed-citation><mixed-citation xml:lang="en">Plakueva A.N., Hromova A.V., Katysheva L.V., Popov D.S. . Biological age of young people living in conditions of European North. Jekologija cheloveka. 2006; 11: 17-20. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Кусякова Р.Ф. Физическая нагрузка и биологический возраст. Международный научно-исследовательский журнал. 2016; 8-5(50): 42-4. https://doi.org/10.18454/IRJ.2016.50.107</mixed-citation><mixed-citation xml:lang="en">Kusjakova R.F. . Physical activity and biological age. Mezhdunarodnyj nauchno-issledovatel’skij zhurnal. 2016; 8-5(50): 42-4. (in Russian). https://doi.org/10.18454/IRJ.2016.50.107</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Артемьева Н.К., Степуренко В.В., Абакумова М.В. Взаимосвязь адекватности питания и параметров биологического возраста спортсменок высокой квалификации. Ресурсы конкурентоспособности спортсменов: теория и практика реализации. 2015; 3: 7-9.</mixed-citation><mixed-citation xml:lang="en">Artem’eva N.K., Stepurenko V.V., Abakumova M.V. The relationship between the adequacy of nutrition and parameters of the biological age of athletes of high qualification. Resursy konkurentosposobnosti sportsmenov: teorija i praktika realizacii. 2015; 3: 7-9. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Зеленин В.А., Павлова Г.В. Биологический возраст человека, как хронобиологический показатель тактики профилактики и лечения заболеваний. Курортная медицина. 2018; 3: 45-7.</mixed-citation><mixed-citation xml:lang="en">Zelenin V.A., Pavlova G.V.Biological age of human, chronobiological indicator of tactics of prevention and treatment of diseases. Kurortnaja medicina. 2018; 3: 45-7. (in Russian).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
