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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medlit</journal-id><journal-title-group><journal-title xml:lang="ru">Гигиена и санитария</journal-title><trans-title-group xml:lang="en"><trans-title>Hygiene and Sanitation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0016-9900</issn><issn pub-type="epub">2412-0650</issn><publisher><publisher-name>Federal Scientific Center of Hygiene named after F.F. Erisman</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47470/0016-9900-2019-98-11-1251-1256</article-id><article-id custom-type="elpub" pub-id-type="custom">medlit-449</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭКСПЕРИМЕНТАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXPERIMENTAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Влияние нелокальной активации и пара-состояний фазы ассоциированной воды на продолжительность жизни гидробионтов Daphnia magna</article-title><trans-title-group xml:lang="en"><trans-title>The impact of non-local activation and associated water phase para-state on an aquatic organisms Daphnia Magna lifetime</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иксанова</surname><given-names>Татьяна Исмаиловна</given-names></name><name name-style="western" xml:lang="en"><surname>Iksanova</surname><given-names>Tatyana I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Научный сотрудник отдела гигиены окружающей среды ФГБУ «ЦСП» Минздрава России, 119121, Москва.</p><p>e-mail: iti-1@mail.ru</p></bio><bio xml:lang="en"><p>Researcher of the environmental health department, Center for Strategic Planning, Russian Ministry of Health, Moscow, 119121, Russian Federation.</p><p>e-mail: iti-1@mail.ru</p></bio><email xlink:type="simple">iti-1@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9050-3757</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каменецкая</surname><given-names>Д. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Kamenetskya</surname><given-names>D. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8750-0686</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стехин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Stekhin</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8766-2773</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлева</surname><given-names>Г. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakovleva</surname><given-names>G. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9616-4517</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кочеткова</surname><given-names>М. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kochetkova</surname><given-names>M. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение «Центр стратегического планирования и управления медико-биологическими рисками здоровью» Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>Center for Strategic Planning, Russian Ministry of Health</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>14</day><month>10</month><year>2020</year></pub-date><volume>98</volume><issue>11</issue><fpage>1251</fpage><lpage>1256</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Иксанова Т.И., Каменецкая Д.Б., Стехин А.А., Яковлева Г.В., Кочеткова М.Г., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Иксанова Т.И., Каменецкая Д.Б., Стехин А.А., Яковлева Г.В., Кочеткова М.Г.</copyright-holder><copyright-holder xml:lang="en">Iksanova T.I., Kamenetskya D.B., Stekhin A.A., Yakovleva G.V., Kochetkova M.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rjhas.ru/jour/article/view/449">https://www.rjhas.ru/jour/article/view/449</self-uri><abstract><sec><title>Введение</title><p>Введение. Работа посвящена изучению влияния магнитного состояния фазы ассоциированной воды, представленной аморфными льдами с изменённым соотношением изомеров в сторону увеличения доли para-воды, и нелокальной активации воды на основе технологии нелокального квантового сопряжения воды c производственным активирующим процессом, на показатели жизнедеятельности гидробионтов Daphnia magna.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Исследования осуществлялись с использованием нелокально активируемой питьевой воды «Si» и концентрата para-воды, приготовленного в гипомагнитных условиях при остаточной плотности магнитного потока не более 20 нТл по технологии производителя. Концентрат para-воды вносился в среду развития гидробионтов в соотношении 9 мл на 1 л исследуемой воды.</p><p>Для получения потомства использовались особи, выводимые на отстоянной водопроводной воде (1-е поколение), и особи, выведенные на воде «Si», – 2-е поколение. Однодневные особи Daphnia magna помещались в количестве 20 шт./л исследуемой воды и весь жизненный цикл содержались в оптимальных условиях: климатостат Р-2 (температура – 20 ± 1 °С, освещённость – 1200–2500 люкс, фотопериод  – 12/12 час). Кормление дафний осуществлялось микроводорослью Chlorella, выращенной на среде «Тамийя»-50% с плотностью D = 0,65–0,72.</p></sec><sec><title>Результаты</title><p>Результаты. Продолжительность жизни гидробионтов Daphnia magna в нелокально активируемой среде жизнедеятельности (воде «Si») увеличивается в среднем на 38 сут в первом поколении и на 50 сут – во втором поколении, а в среде с потенцирующей добавкой para-ассоциатов воды на 58 сут (первое поколение) и 41 сут (второе поколение). Показатели продолжительности жизни гидробионтов находятся в отрицательной корреляционной зависимости с изменениями значений окислительно-восстановительного потенциала (Еh) среды развития гидробионтов – kкорр. = –0,993 (1-е поколение). Нелокальная активация воды и спин-модификации её ассоциированной фазы para-изомерами демонстрируют увеличение продуктивности гидробионтов:</p></sec><sec><title>Заключение</title><p>Заключение. Из результатов исследования следует, что определяющим фактором среды развития гидробионтов является её квантовое сопряжение с источниками электронов во внешней среде. Это предопределяет значимость квантового сопряжения воды с природными экосистемами, влияющего на клеточный метаболизм. Спиновая para-модификация фазы ассоциированной воды приводит к дополнительному увеличению продолжительности жизни гидробионтов в первом поколении. Во втором поколении влияние para-воды сопровождается некоторым снижением как продолжительности жизни гидробионтов, так и их продуктивности.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. The work is devoted to the study of associated water phase magnetic state influence, represented by amorphous ice with a modified ratio of isomers in the increasing of para-water proportion, and non-local water activation based on the technology of non-local quantum water conjugation with the production activating process, on the vital hydrobionts Daphnia magna signs. </p></sec><sec><title>Material and methods</title><p>Material and methods. The studies were carried out using non-locally activated drinking water “Si” and a para-water concentrate prepared in hypomagnetic conditions at a residual magnetic flux density not more than 20ntl according to the manufacturer’s technology. The para-water concentrate was introduced into the hydrobionts medium in the ratio of 9 ml per 1 liter of water under study.</p><p>To obtain offspring, individuals were used, derived on the settled tap water (1st generation) and individuals, derived on the water “Si” - 2nd generation. One-day individuals of Daphnia magna were placed in the amount of 20pcs/l of the studied water and the entire life cycle were kept in optimal conditions: climatostat P-2 (temperature - 20±1°C, illumination – 1200-2500lux, photoperiod - 12/12) hour. Feeding of Daphnia was carried out by Chlorella microalgae grown on the medium “Tamiya”-50% with a density D=0.65-0.72.</p></sec><sec><title>Results</title><p>Results. The life expectancy of Daphnia magna hydrobionts in the non-locally activated environment (water “Si”) increases by an average of 38 days in the first generation and 50 days in the second generation, and in an environment with a potentiating additive para-water associates for 58 days (first generation) and 41 days (second generation).The life expectancy of aquatic animals is related by negative correlation with the change in values of the oxidation-reductant potential (Eh) of the environment of hydrobionts development (kCorr.=-0.993 (1st generation). Both non-local water activation and spin-modification of its associated phase by para-isomers demonstrate an increase in the hydrobionts productivity: </p></sec><sec><title>Conclusion</title><p>Conclusion. From the results it follows that the determining factor in the hydrobionts medium is its quantum coupling with electron sources in the external environment. This determines the importance of water quantum coupling with natural ecosystems, affecting cellular metabolism. Spin para modification of the associated water phase leads to an additional increase in the hydrobionts life expectancy in the first generation. In the second generation, the influence of para-water is accompanied by some decrease in both the life hydrobionts expectancy and their productivity.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>гидробионты Daphnia magna</kwd><kwd>геронтология</kwd><kwd>ortho-вода и para-вода</kwd><kwd>фаза ассоциированной воды</kwd><kwd>нелокальная активация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Daphnia magna hydrobionts</kwd><kwd>gerontology</kwd><kwd>ortho-water and para-water</kwd><kwd>associated water phase</kwd><kwd>nonlocal activation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Авдеева Л.В., Кольтовер В.К. Ядерный спиновый катализ в живой природе. Вестник Московского университета. Химия. 2016; 57 (3): 145-53.</mixed-citation><mixed-citation xml:lang="en">Avdeeva L.V., Koltover V.K. Nuclear spin catalysis in nature. Vestnik Moskovskogo Universiteta. 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