medlitГигиена и санитарияHygiene and Sanitation0016-99002412-0650Federal Scientific Center of Hygiene named after F.F. Erisman10.47470/0016-9900-2025-104-12-1733-1740mrgimlmedlit-5350Research ArticleПРОФИЛАКТИЧЕСКАЯ ТОКСИКОЛОГИЯ И ГИГИЕНИЧЕСКОЕ НОРМИРОВАНИЕPREVENTIVE TOXICOLOGY AND HYGIENIC STANDARTIZATIONК вопросу о внесении инсектицида хлорпирифоса в Приложение А Стокгольмской конвенции о стойких органических загрязнителях (обзор литературы)On the issue of adding the insecticide chlorpyrifos to Appendix A of the Stockholm Convention on Persistent Organic Pollutants (literature review)https://orcid.org/0000-0002-9959-6507РакитскийВалерий НиколаевичRakitskiiValerii N.

Доктор мед. наук, профессор, академик РАН, научный руководитель Института гигиены, токсикологии пестицидов и химической безопасности ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, 141014, Мытищи, Россия

e-mail: rakitskii.vn@fncg.ru

DSc (Medicine), professor, academician of the RAS, scientific director of the Institute of Hygiene, Toxicology of Pesticides and Chemical Safety of the Federal Scientific Center of Hygiene named after F.F. Erisman, Mytishchi, 141014, Russian Federation

e-mail: rakitskii.vn@fncg.ru

rakitskii.vn@fncg.ruhttps://orcid.org/0000-0002-0444-1095ВещемоваТатьяна ЕвгеньевнаVeshchemovaTatiana E.

Канд. мед. наук, ст. науч. сотр. отд. гигиены труда Института гигиены, токсикологии пестицидов и химической безопасности ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, 141014, Мытищи, Россия

e-mail: veshchemova.te@fncg.ru

PhD (Medicine), senior researcher, Occupational health department, Institute of Hygiene, Pesticide Toxicology and Chemical Safety, Federal Scientific Center of Hygiene named after F.F. Erisman, Mytishchi, 141014, Russian Federation

e-mail: veshchemova.te@fncg.ru

veshchemova.te@fncg.ruhttps://orcid.org/0000-0002-0519-3257ЧхвиркияЕлена ГригорьевнаChkhvirkiyaElena G.

Доктор мед. наук, профессор, гл. науч. сотр. отд. токсикологии ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, 141014, Мытищи, Россия

e-mail: chkhvirkiya.eg@fncg.ru

DSc (Medicine), professor, chief researcher, Toxicology department, Scientific Center of Hygiene named after F.F. Erisman, Mytishchi, 141014, Russian Federation

e-mail: chkhvirkiya.eg@fncg.ru

chkhvirkiya.eg@fncg.ruhttps://orcid.org/0000-0003-1539-1633МасальцевГлеб ВикторовичMasaltsevGleb V.

Канд. биол. наук, зав. отд. токсикологии Института гигиены, токсикологии пестицидов и химической безопасности ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, 141014, Мытищи, Россия

e-mail: masalcev.gv@fncg.ru

PhD (Biology), head, Toxicology department, Institute of Hygiene, pesticide toxicology and chemical safety, Federal Scientific Center of Hygiene named after F.F. Erisman, Mytishchi, 141014, Russian Federation

e-mail: masalcev.gv@fncg.ru

masalcev.gv@fncg.ruФБУН «Федеральный научный центр гигиены имени Ф.Ф. Эрисмана» РоспотребнадзораРоссияFederal Scientific Center of Hygiene named after F.F. ErismanRussian Federation2025200120261041217331740Copyright © Ракитский В.Н., Вещемова Т.Е., Чхвиркия Е.Г., Масальцев Г.В., 20262026Ракитский В.Н., Вещемова Т.Е., Чхвиркия Е.Г., Масальцев Г.В.Rakitskii V.N., Veshchemova T.E., Chkhvirkiya E.G., Masaltsev G.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.rjhas.ru/jour/article/view/5350

Обзор баз данных РИНЦ и КиберЛенинка, а также интернет-ресурсов международных организаций (ВОЗ и др.) и регуляторных агентств стран, представленных в обзоре (Агентство по охране окружающей среды США и др.), с глубиной поиска 2018–2025 гг. выявил разногласия в подходах мировых регуляторов к минимизации потенциальных рисков при применении хлорпирифоса (ХПФС), несмотря на предложение Европейского союза о включении его в список стойких органических загрязнителей (СОЗ) Стокгольмской конвенции после появления новой информации о потенциальной опасности этого соединения для ребёнка в утробе матери. В настоящее время полный запрет ХПФС ввели страны с холодным или умеренным климатом (Канада, ЕС), а также страны-экспортёры, осуществляющие торговлю с ЕС (Вьетнам, Индонезия, Малайзия, Непал, Перу, Таиланд, Турция, Чили, Шри-Ланка). Российская Федерация наряду с США и Австралией входит в список стран, значительно ограничивших применение ХПФС. В сельском хозяйстве Мексики, Китая, Бразилии по-прежнему используется хлорпирифос. Несмотря на финансовую доступность некоторых альтернативных химических средств защиты растений как замены для некоторых сфер применения ХПФС, на рынке нет полного аналога со столь же широким спектром действия, что может сдерживать развивающиеся страны от ограничения или запрета ХПФС до официального его включения в Приложение А Стокгольмской конвенции о стойких органических загрязнителях, несмотря на потенциальные риски, которые он может представлять для здоровья населения.

Участие авторов

Участие авторов: Ракитский В.Н., Чхвиркия Е.Г. – концепция и дизайн исследования; Вещемова Т.Е., Масальцев Г.В. – концепция и дизайн исследования, сбор и анализ данных литературы, написание текста. Все соавторы – утверждение окончательного варианта статьи, ответственность за целостность всех её частей.

Конфликт интересов

Конфликт интересов. Авторы декларируют отсутствие явных и потенциальных конфликтов интересов в связи с публикацией данной статьи.

Финансирование

Финансирование. Литературный обзор выполнен в рамках отраслевой программы Роспотребнадзора «Научное обоснование национальной системы обеспечения санитарно-эпидемиологического благополучия, управления рисками здоровью и повышения качества жизни населения России» (2021–2025 гг.).

Поступила

Поступила: 13.10.2025 / Принята к печати: 02.12.2025 / Опубликована: 15.01.2026

The Russian Science Citation Index and CyberLeninka, as well as the Internet resources of international organizations (WHO, etc.) and regulatory agencies of the countries listed in the review (US Environmental Protection Agency, etc.) with a search depth from 2018-2025 revealed differences in the approaches of global regulators to minimizing potential risks from the use of chlorpyrifos (CPFS), despite the European Union’s proposal to include it in the list of persistent organic pollutants (POPs) of the Stockholm Convention after new information emerged about its potential danger to the unborn child. To date, a complete ban on CPFS has been introduced by countries with a cold or temperate climate (Canada, EU), as well as exporting countries trading with the EU (Vietnam, Indonesia, Malaysia, Nepal, Peru, Thailand, Turkey, Chile, Sri Lanka). At the same time, the Russian Federation, along with the United States of America and Australia, have significantly restricted the use of CPFS. The use of chlorpyrifos in agriculture remains unchanged in Mexico, China, and Brazil. Despite the affordability of some alternative chemical plant protection products available for some applications of CPFS, there is no complete analogue with the same broad spectrum of action on the market, which may deter developing countries from restricting or banning CPFS until it is officially included in Annex A of the Stockholm Convention on Persistent Organic Pollutants, despite the potential risks it may pose to the safety of the unborn child.

Contribution

Contribution: Rakitskii V.N., Veshchemova T.E. – concept and design of the study, collection and analysis of literary data, writing the text; Chkhvirkiya E.G., Masaltsev G.V. – concept and design of the study, collection and analysis of literary data, writing the text. All authors are responsible for the integrity of all parts of the manuscript and approval of the manuscript final version.

Conflict of interest

Conflict of interest. The authors declare no conflict of interest.

Funding

Funding. The study was carried out within the framework of the industry programs of Rospotrebnadzor “Scientific justification of the national system for ensuring sanitary and epidemiological well-being, health risk management and improving the quality of life of the population of Russia” (2021-2025).

Received

Received: October 13, 2025 / Accepted: December 2, 2025 / Published: January 15, 2026

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The authors declare that there are no conflicts of interest present.