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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medlit</journal-id><journal-title-group><journal-title xml:lang="ru">Гигиена и санитария</journal-title><trans-title-group xml:lang="en"><trans-title>Hygiene and Sanitation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0016-9900</issn><issn pub-type="epub">2412-0650</issn><publisher><publisher-name>Federal Scientific Center of Hygiene named after F.F. Erisman</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47470/0016-9900-2018-97-5-424-428</article-id><article-id custom-type="elpub" pub-id-type="custom">medlit-563</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГИГИЕНА ОКРУЖАЮЩЕЙ СРЕДЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ENVIRONMENTAL HYGIENE</subject></subj-group></article-categories><title-group><article-title>Перспективы первичной профилактики колоректального рака на основе оценки значимости факторов, ассоциированных с риском развития этой патологии</article-title><trans-title-group xml:lang="en"><trans-title>Perspectives of the primary prevention of colorectal cancer based on the assessment of the impact of factors associated with the risk of this pathology</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вильмс</surname><given-names>Елена Анатольевна</given-names></name><name name-style="western" xml:lang="en"><surname>Vilms</surname><given-names>Elena A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Канд. мед. наук, доц. каф. эпидемиологии, ФГБОУ ВО «Омский государственный медицинский университет» Минздрава России, 644099, Омск.</p><p>e-mail: wilms26@yandex.ru</p></bio><bio xml:lang="en"><p>MD, Ph.D., Associate Professor of the Department of Epidemiology of the Omsk State Medical University, Омск; 644099, Russian Federation.</p><p>e-mail: wilms26@yandex.ru</p></bio><email xlink:type="simple">wilms26@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Турчанинов</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Turchaninov</surname><given-names>D. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стасенко</surname><given-names>В. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Stasenko</surname><given-names>V. L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ширлина</surname><given-names>Н. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Shirlina</surname><given-names>N. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Омский государственный медицинский университет» Минздрава России</institution></aff><aff xml:lang="en"><institution>Omsk State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>20</day><month>10</month><year>2020</year></pub-date><volume>97</volume><issue>5</issue><fpage>424</fpage><lpage>428</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Вильмс Е.А., Турчанинов Д.В., Стасенко В.Л., Ширлина Н.Г., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Вильмс Е.А., Турчанинов Д.В., Стасенко В.Л., Ширлина Н.Г.</copyright-holder><copyright-holder xml:lang="en">Vilms E.A., Turchaninov D.V., Stasenko V.L., Shirlina N.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rjhas.ru/jour/article/view/563">https://www.rjhas.ru/jour/article/view/563</self-uri><abstract><p>Проведён анализ анкетных данных (характеризующих образ жизни, место проживания, пищевой рацион, имеющиеся заболевания, симптомы) пациентов с установленным диагнозом колоректальный рак (КРР) и лиц группы сравнения без этого диагноза. Определены факторы (признаки), ассоциированные с риском развития колоректального рака, оценена вероятность их обнаружения у больных и здоровых, их диагностическая ценность (информативность). Установлены наиболее информативные, ассоциированные с риском развития КРР для жителей Омской области факторы (признаки): смена региона проживания, пристрастие к жирной пище, прохождение последнего медосмотра более четырёх лет назад, наличие родственников первой линии с колоректальным раком, сведения о состоянии здоровья (положительный результат исследования кала на скрытую кровь, симптомы наличия примеси крови в кале, ложные позывы на стул, наличие полипов, геморроя, трещин прямой кишки).</p></abstract><trans-abstract xml:lang="en"><p>The analysis of personal data (characterizing a way of life, area of residence, food ration, an available disease, symptoms) of patients with the established diagnosis of colorectal cancer (CRC) and persons of the comparison group without this diagnosis was carried out. The factors (signs) associated with the risk of the development of colorectal cancer were determined, the probability of their detection in patients and healthy, their diagnostic value (informative value) was estimated. The most informative factors associated with the risk of the development of CRC were found for residents of the Omsk region: changing the region of residence, addiction to fatty food, passing the last prophylactic medical examination more than 4 years ago, having relatives of the first line with colorectal cancer, information on the state of health (positive the result of examination of feces for latent blood, symptoms of the presence of admixture of blood in the stool, false desires for stool presence of polyps, hemorrhoids, cracks in the rectum).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>колоректальный рак</kwd><kwd>эпидемиология</kwd><kwd>факторы риска</kwd><kwd>отношение правдоподобия</kwd><kwd>диагностическая информативность</kwd><kwd>Омская область</kwd></kwd-group><kwd-group xml:lang="en"><kwd>colorectal cancer</kwd><kwd>epidemiology</kwd><kwd>risk factors</kwd><kwd>likelihood ratio</kwd><kwd>diagnostic information Omsk region</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Jemal A., Siegel R., Ward E., Hao Y., Xu J., Thun M.J. 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