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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medlit</journal-id><journal-title-group><journal-title xml:lang="ru">Гигиена и санитария</journal-title><trans-title-group xml:lang="en"><trans-title>Hygiene and Sanitation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0016-9900</issn><issn pub-type="epub">2412-0650</issn><publisher><publisher-name>Federal Scientific Center of Hygiene named after F.F. Erisman</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47470/0016-9900-2018-97-5-445-448</article-id><article-id custom-type="elpub" pub-id-type="custom">medlit-567</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГИГИЕНА ТРУДА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OCCUPATIONAL HYGIENE</subject></subj-group></article-categories><title-group><article-title>Лёгочный газообмен и кислотно-щелочное состояние крови при применении средств индивидуальной защиты органов дыхания</article-title><trans-title-group xml:lang="en"><trans-title>Pulmonary gas exchange and acid-base status of blood under the use of means for individual protection of respiratory organs</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6769-8277</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бяловский</surname><given-names>Юрий Юльевич</given-names></name><name name-style="western" xml:lang="en"><surname>Byalovsky</surname><given-names>Yury Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Д-р мед. наук, зав. каф. патофизиологии ФГБОУ ВО «РязГМУ» Минздрава России.</p><p>e-mail: b_uu@mail.ru</p></bio><bio xml:lang="en"><p>MD, Ph.D., DSci., Head of the Department of Pathophysiology of the State Medical University of the Ryazan, 390026, Russian Federation.</p><p>e-mail: b_uu@mail.ru</p></bio><email xlink:type="simple">b_uu@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6023-7523</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Булатецкий</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bulatetsky</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1258-9807</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кирюшин</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kiryushin</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4510-2890</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прохоров</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Prokhorov</surname><given-names>N. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7011-4765</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абросимов</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Abrosimov</surname><given-names>V. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4445-4480</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Глотов</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Glotov</surname><given-names>S. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0273-4388</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пономарёва</surname><given-names>И. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Ponomareva</surname><given-names>I. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7459-5380</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Субботин</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Subbotin</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО РязГМУ Минздрава России</institution></aff><aff xml:lang="en"><institution>Ryazan State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАОУ ВО Первый МГМУ им. И.М. Сеченова Минздрава России (Сеченовский Университет)</institution></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>20</day><month>10</month><year>2020</year></pub-date><volume>97</volume><issue>5</issue><fpage>445</fpage><lpage>448</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бяловский Ю.Ю., Булатецкий С.В., Кирюшин В.А., Прохоров Н.И., Абросимов В.Н., Глотов С.И., Пономарёва И.Б., Субботин С.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Бяловский Ю.Ю., Булатецкий С.В., Кирюшин В.А., Прохоров Н.И., Абросимов В.Н., Глотов С.И., Пономарёва И.Б., Субботин С.В.</copyright-holder><copyright-holder xml:lang="en">Byalovsky Y.Y., Bulatetsky S.V., Kiryushin V.A., Prokhorov N.I., Abrosimov V.N., Glotov S.I., Ponomareva I.B., Subbotin S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rjhas.ru/jour/article/view/567">https://www.rjhas.ru/jour/article/view/567</self-uri><abstract><p>Проведено исследование, целью которого было изучение влияния длительности тренировок к использованию средств индивидуальной защиты органов дыхания на показатели лёгочного газообмена и кислотно-щелочного состояния крови. Моделирование условий применения средств индивидуальной защиты органов дыхания осуществлялось с помощью инспираторных сопротивлений дыханию величиной 40, 60, 70 и 80% Pmmax. В исследовании участвовало 38 практически здоровых испытуемых мужского пола в возрасте от 20 до 36 лет. По результатам исследования показано, что при использовании средств индивидуальной защиты органов дыхания предварительная тренировка имеет существенное значение. У испытуемых, не прошедших предварительной тренировки, характер дыхательного рисунка мало изменялся при использовании средств индивидуальной защиты органов дыхания. У испытуемых, прошедших предварительную тренировку, отмечалась адаптивная перестройка дыхательного рисунка, состоявшая в урежении дыхательных движений по мере роста респираторного сопротивления. Предварительная тренировка к действию дополнительного сопротивления дыханию изменяла лёгочный газообмен и кислотно-щелочное состояние крови. Тренированные испытуемые имели более высокие значения напряжения углекислого газа и более низкие значения напряжения кислорода в крови. У них обнаруживался больший дефицит буферных оснований плазмы по сравнению с нетренированными. Данный факт свидетельствовал о том, что предварительная тренировка к использованию средств индивидуальной защиты органов дыхания (долговременная адаптация) изменяла газовый состав и кислотно-щелочное состояние крови на более экономный режим расхода буферных систем. На основании полученных данных выдвинуто положение о том, что при использовании средств индивидуальной защиты органов дыхания целесообразно проведение предварительной тренировки к увеличенному сопротивлению дыхания.</p></abstract><trans-abstract xml:lang="en"><p>The aim of the study was to evaluate the effect of the duration of training on the use of personal respiratory protective equipment on indices of pulmonary gas exchange. Simulation of conditions for the use of personal respiratory protective equipment was carried out at the inspiratory resistance of 40, 60, 70 and 80% Pmmax. The study included 38 healthy male subjects aged 20 to 36 years. According to the results of the study, under the use of personal protective equipment for the respiratory system, preliminary training was shown to be essential. In the subjects without preliminary training, the use of personal protective equipment was followed by a weak change in the nature of the respiratory pattern. After the preliminary training subjects had an adaptive rearrangement of the respiratory pattern, consisted of the decline in breathing movements as the respiratory resistance increased. Preliminary training to the exposure of additional resistance to breathing, altered pulmonary gas exchange and acid-base state of blood. The trained subjects had higher pCO2 blood values and lower values of pO2. They showed a greater deficit of buffer bases of plasma compared to untrained ones. This fact testified the preliminary training for the use of personal respiratory protective equipment (long-term adaptation) changed the gas composition and acid-base state of the blood to be a more economical mode of the discharge of buffer systems. On the basis of the data obtained, the preliminary training for increased respiratory resistance was suggested to be advisable before the using personal respiratory protective equipment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дополнительное респираторное сопротивление</kwd><kwd>лёгочный газообмен</kwd><kwd>кислотно-щелочное состояние</kwd><kwd>средства индивидуальной защиты органов дыхания</kwd></kwd-group><kwd-group xml:lang="en"><kwd>additional respiratory resistance</kwd><kwd>pulmonary gas exchange</kwd><kwd>acid-base state</kwd><kwd>personal respiratory protective equipment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Каминский С.Л. Основы рациональной защиты органов дыхания на производстве. М.: Проспект Науки; 2007: 208.</mixed-citation><mixed-citation xml:lang="en">Kaminsky S.L. Basics of rational respiratory protection in the workplace. 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