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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medlit</journal-id><journal-title-group><journal-title xml:lang="ru">Гигиена и санитария</journal-title><trans-title-group xml:lang="en"><trans-title>Hygiene and Sanitation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0016-9900</issn><issn pub-type="epub">2412-0650</issn><publisher><publisher-name>Federal Scientific Center of Hygiene named after F.F. Erisman</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47470/0016-9900-2017-96-11-1049-1053</article-id><article-id custom-type="elpub" pub-id-type="custom">medlit-948</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГИГИЕНА ОКРУЖАЮЩЕЙ СРЕДЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ENVIRONMENTAL HYGIENE</subject></subj-group></article-categories><title-group><article-title>Влияние железа в питьевой воде на заболеваемость населения г. Орла</article-title><trans-title-group xml:lang="en"><trans-title>Effect of iron in drinking water on the morbidity rate in the population of the city of Orel</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6751-6149</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Егорова</surname><given-names>Наталия Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Egorova</surname><given-names>Nataliya A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Д-р мед. наук, вед. науч. сотр. лаб. диагностики экологически зависимой патологии с группой гигиенической экспертизы ФГБУ «Центр стратегического планирования и управления медико-биологическими рисками здоровью» Минздрава России, 119991, Москва, Россия.</p><p>e-mail: tussy@list.ru</p></bio><bio xml:lang="en"><p>Dr. Sci. Med., leading researcher of the Laboratory of environment-dependent pathology with group of the hygiene expertise of the Centre for Strategic Planning and Management of Biomedical Health Risks, Moscow, 119991, Russian Federation.</p><p>e-mail: tussy@list.ru</p></bio><email xlink:type="simple">tussy@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7413-2901</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Канатникова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kanatnikova</surname><given-names>N. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Центр стратегического планирования и управления медико-биологическими рисками здоровью» Минздрава России</institution></aff><aff xml:lang="en"><institution>Centre for Strategic Planning and Management of Biomedical Health Risks</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФБУЗ «Центр гигиены и эпидемиологии в Орловской области»</institution></aff><aff xml:lang="en"><institution>The Centre of Hygiene and Epidemiology in the Orel Region</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>21</day><month>10</month><year>2020</year></pub-date><volume>96</volume><issue>11</issue><fpage>1049</fpage><lpage>1053</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Егорова Н.А., Канатникова Н.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Егорова Н.А., Канатникова Н.В.</copyright-holder><copyright-holder xml:lang="en">Egorova N.A., Kanatnikova N.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rjhas.ru/jour/article/view/948">https://www.rjhas.ru/jour/article/view/948</self-uri><abstract><p>Население г. Орла использует в питьевых целях подземные воды Задонско-Оптуховского и Воронежско-Ливенского водоносных комплексов с природным содержанием общего железа, среднегодовые уровни которого в период наблюдения 2007–2015 гг. превышали ПДК 0,3 мг/л в 1,03–1,43 раза с максимумом 3,67–17,7 раза. Хотя повышенное содержание железа в питьевой воде принято рассматривать преимущественно с точки зрения изменений органолептических свойств воды, в ряде гигиенических исследований последних лет показано, что длительное употребление воды, в которой превышены ПДК железа, способствует увеличению общей заболеваемости, развитию болезней крови, кожи и подкожной клетчатки, костно-мышечной системы, органов пищеварения, мочеполовой системы, аллергических заболеваний. В литературе имеются многочисленные публикации, рассматривающие причины возникновения и повреждающее действие перегрузки организма человека железом, и во многом объясняющие возможность развития перечисленных выше видов патологии. Цель настоящей работы — выявление связей между уровнями содержания общего железа в питьевой воде и заболеваемостью населения г. Орла. Исследования проводили с использованием корреляционного анализа. Для периода наблюдения с 2007 по 2015 г. выявлены достоверные прямые корреляционные связи среднегодовых концентраций железа в питьевой воде с общей заболеваемостью детского и взрослого населения, а также с 11 видами неинфекционных патологий, в том числе болезнями органов дыхания, мочеполовой системы, атопическим дерматитом и реактивными артропатиями и экземой у детей; болезнями крови и кроветворных органов, реактивными артропатиями, гастритом и дуоденитом у подростков; стенокардией, цереброваскулярными болезнями, сахарным диабетом, гастритом, дуоденитом и болезнями печени у взрослых. Коэффициенты корреляции составили 0,66–0,86 с достоверностью &lt;0,01–&lt;0,05. Возможно, эти связи носят причинно-следственный характер, что находит подтверждение в сходных результатах, полученных в Тульской области, Приморском крае и Свердловской области, где для водоснабжения населения используются подземные воды с повышенным содержанием железа. По-видимому, следует более осторожно подходить к гигиенической оценке повышенного содержания железа в питьевой воде, не ограничиваясь его влиянием на органолептические свойства воды, но уделяя внимание возможным этиологическим связям с заболеваемостью населения.</p></abstract><trans-abstract xml:lang="en"><p>The population of the city of Orеl consumes drinking underground water of Zadonsko-Optuhovsky and Voronezh-Livny aquifers with natural iron content, annual mean levels of which over the observation period from 2007 to  2015 exceeded the maximum allowable concentration (0.3 mg/l) by 1.03 to 1.43 times, with a maximum of 3.67 to 17.7 times. Although an elevated iron content in drinking water has been considered primarily in terms of organoleptic changes, several sanitary studies of recent years have revealed the prolonged use of water containing iron in concentrations, which exceed the maximum allowable ones, to scale up overall morbidity as well as the development of blood, skin and subcutaneous tissue diseases, musculoskeletal problems, digestive,  urogenital system and allergic disorders. There are many reports concerning causes  and the harm to human organism due to iron overload, and largely explanation of the possibility of developing the above types of pathology. The purpose of the study is to identify relationships between levels of total iron content in drinking water and the morbidity rate of the population of the city of Orel. Investigations were executed with the use a correlation analysis. For the period from 2007 to 2015, there were revealed direct correlation relationships between the annual average concentrations of iron in drinking water and the total morbidity  rate of children and adults as well as 11 types of non-infectious pathologies, including diseases of the  respiratory and urogenital system, atopic dermatitis, reactive arthropathies and eczema in children; diseases of blood and blood-forming organs, reactive arthropathies, gastritis and duodenitis in adolescents, stenocardia, cerebrovascular diseases, diabetes mellitus, gastritis, duodenitis and liver diseases in adults. The correlation coefficients amounted to from 0.66 to 0.86, with an accuracy of 0.01-0.05. These relationships may be causal in nature, as it was proved by similar results obtained in the Tula region, Primorsky Krai, and Sverdlovsk region where the population uses ground water with a high iron content. Apparently, it should be more careful in the assessment of the elevated iron content in drinking water from a hygienic viewpoint and must focus, among other things, on its possible causal relations with the morbidity rates of the population, rather than scrutinizing primarily its impact on the organoleptic water properties.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>питьевая вода из подземных водоисточников</kwd><kwd>общее железо</kwd><kwd>заболеваемость населения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>drinking water from underground water sources</kwd><kwd>total iron</kwd><kwd>morbidity rate of population</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">WHO. Iron in drinking water. Geneva; 2003</mixed-citation><mixed-citation xml:lang="en">WHO. Iron in drinking water. 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