Генотоксические биомаркеры у сотрудников патологоанатомических лабораторий, работающих с формальдегидом (систематический обзор)
https://doi.org/10.47470/0016-9900-2020-99-8-792-802
Аннотация
Ключевые слова
Об авторах
Наталья Вахитовна Еремина
ФГБНУ «Научно-исследовательский институт фармакологии имени В.В. Закусова»
Россия
Россия
Кандидат биол. наук, ст. науч. сотр. лаб. лекарственной токсикологии ФГБНУ «НИИ фармакологии им. В.В. Закусова», 125315, Москва.
e-mail: neremina@panacelalabs.com
А. К. Жанатаев
ФГБНУ «Научно-исследовательский институт фармакологии имени В.В. Закусова»
Россия
Россия
А. Д. Дурнев
ФГБНУ «Научно-исследовательский институт фармакологии имени В.В. Закусова»
Россия
Россия
Список литературы
1. d’Ettorre G., Criscuolo M., Mazzotta M. Managing Formaldehyde indoor pollution in anatomy pathology departments. Work. 2017; 56(3): 397-402. https://doi.org/10.3233/WOR-172505
2. Fenech M., Nersesyan A., Knasmueller S. A systematic review of the association between occupational exposure to formaldehyde and effects on chromosomal DNA damage measured using the cytokinesis-block micronucleus assay in lymphocytes. Mutat. Res. 2016; 770(Pt. A): 46-57. https://doi.org/10.1016/j.mrrev.2016.04.005
3. Swenberg J.A., Kerns W.D., Mitchell R.I., Gralla E.J., Pavkov K.L. Induction of squamous cell carcinomas of the rat nasal cavity by inhalation exposure to formaldehyde vapor. Cancer Res. 1980; 40(9): 3398-402.
4. U.S. Environmental Protection Agency, Office of Air and Radiation. Report to Congress on Indoor Air Quality. Volume II. Assessment and Control of Indoor Air Pollution. EPA 400-1-89-001C. Washington: USEPAOAR; 1989.
5. IARC Monographs on the Evaluation of Carcinogenic Risks to Human. Volume 88: Formaldehyde, 2-Butoxyethanol and 1-tert-Butoxy-2-propanol. Lyon: WHO; 2006.
6. IARC (International Agency for Research on Cancer). Formaldehyde. In: IARC, ed. A Review of Human Carcinogens, Chemical Agents and Related Occupations, IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Part F of Vol. 100. Lyon: WHO; 2012: 401-35.
7. NTP (National Toxicology Program). Report on Carcinogens. US Department of Health and Human Services, Public Health Service, National Toxicology Program, Formaldehyde. Research Triangle Park; 2011: 195-205.
8. Zhang L., Steinmaus C., Eastmond D.A., Xin X.K., Smith M.T. Formaldehyde exposure and leukemia: a new meta-analysis and potential mechanisms. Mutat. Res. 2009; 681(2-3): 150-68. https://doi.org/10.1016/j.mrrev.2008.07.002
9. Heck H.d., Casanova M. The implausibility of leukemia induction by formaldehyde: a critical review of the biological evidence on distant-site toxicity. Regul. Toxicol. Pharmacol. 2004; 40(2): 92-106. https://doi.org/10.1016/j.yrtph.2004.05.001
10. Pyatt D., Natelson E., Golden R. Is inhalation exposure to formaldehyde a biologically plausible cause of lymphohematopoietic malignancies? Regul. Toxicol. Pharmacol. 2008; 51(1): 119-33. https://doi.org/10.1016/j.yrtph.2008.03.003
11. Franks S.J. A mathematical model for the absorption and metabolism of formaldehyde vapour by humans. Toxicol. Appl. Pharmacol. 2005; 206(3): 309-20. https://doi.org/10.1016/j.taap.2004.11.012
12. National Toxicology Program. Final report on carcinogens background document for formaldehyde. Rep. Carcinog. Backgr. Doc. 2010; (10-5981): i-512.
13. Lu K., Ye W., Zhou L., Collins L.B., Chen X., Gold A. et al. Structural characterization of formaldehyde-induced cross-links between amino acids and deoxynucleosides and their oligomers. J. Am. Chem. Soc. 2010; 132(10): 3388-99. https://doi.org/10.1021/ja908282f
14. Zhang L., Freeman L.E., Nakamura J., Hecht S.S., Vandenberg J.J., Smith M.T. et al. Formaldehyde and leukemia: epidemiology, potential mechanisms, and implications for risk assessment. Environ. Mol. Mutagen. 2010; 51(3): 181-91. https://doi.org/10.1002/em.20534
15. Swenberg J.A., Moeller B.C., Lu K., Rager J.E., Fry R.C., Starr T.B. Formaldehyde carcinogenicity research: 30 years and counting for mode of action, epidemiology, and cancer risk assessment. Toxicol. Pathol. 2013; 41(2): 181-9. https://doi.org/10.1177/0192623312466459
16. Ye X., Ji Z., Wei C., McHale C.M., Ding S., Thomas R. et al. Inhaled formaldehyde induces DNA-protein crosslinks and oxidative stress in bone marrow and other distant organs of exposed mice. Environ. Mol. Mutagen. 2013; 54(9): 705-18. https://doi.org/10.1002/em.21821
17. Bonassi S., Norppa H., Ceppi M., Strömberg U., Vermeulen R., Znaor A. et al. Chromosomal aberration frequency in lymphocytes predicts the risk of cancer: results from a pooled cohort study of 22 358 subjects in 11 countries. Carcinogenesis. 2008; 29(6): 1178-83. https://doi.org/10.1093/carcin/bgn075
18. Bonassi S., Znaor A., Ceppi M., Lando C., Chang W.P., Holland N. et al. An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans. Carcinogenesis. 2007; 28(3): 625-31. https://doi.org/10.1093/carcin/bgl177
19. Vodicka P., Polivkova Z., Sytarova S., Demova H., Kucerova M., Vodickova L. et al. Chromosomal damage in peripheral blood lymphocytes of newly diagnosed cancer patients and healthy controls. Carcinogenesis. 2010; 31(7): 1238-41. https://doi.org/10.1093/carcin/bgq056
20. Mateuca R., Lombaert N., Aka P.V., Decordier I., Kirsch-Volders M. Chromosomal changes: induction, detection methods and applicability in human biomonitoring. Biochimie. 2006; 88(11): 1515-31. https://doi.org/10.1016/j.biochi.2006.07.004
21. Albertini R.J., Anderson D., Douglas G.R., Hagmar L., Hemminki K., Merlo F. et al. IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans. International Programme on Chemical Safety. Mutat. Res. 2000; 463(2): 111-72. https://doi.org/10.1016/s1383-5742(00)00049-1
22. Collins A.R. The comet assay for DNA damage and repair: principles, applications, and limitations. Mol. Biotechnol. 2004; 26(3): 249-61. https://doi.org/10.1385/MB:26:3:249
23. Ying C.J., Yan W.S., Zhao M.Y., Ye X.L., Xie H., Yin S.Y. et al. Micronuclei in nasal mucosa, oral mucosa and lymphocytes in students exposed to formaldehyde vapor in anatomy class. Biomed. Environ. Sci. 1997; 10(4): 451-5.
24. Vasudeva N., Anand C. Cytogenetic evaluation of medical students exposed to formaldehyde vapor in the gross anatomy dissection laboratory. J. Am. Coll. Health. 1996; 44(4): 177-9. https://doi.org/10.1080/07448481.1996.9937526
25. Costa S., Costa C., Madureira J., Valdiglesias V., Teixeira-Gomes A., Guedes de Pinho P. et al. Occupational exposure to formaldehyde and early biomarkers of cancer risk, immunotoxicity and susceptibility. Environ. Res. 2019; 179(Pt. A): 108740. https://doi.org/10.1016/j.envres.2019.108740
26. Costa S., García-Lestón J., Coelho M., Coelho P., Costa C., Silva S. et al. Cytogenetic and immunological effects associated with occupational formaldehyde exposure. J. Toxicol. Environ. Health A. 2013; 76(4-5): 217-29. https://doi.org/10.1080/15287394.2013.757212
27. Ladeira C., Viegas S., Carolino E., Gomes M.C., Brito M. The influence of genetic polymorphisms in XRCC3 and ADH5 genes on the frequency of genotoxicity biomarkers in workers exposed to formaldehyde. Environ. Mol. Mutagen. 2013; 54(3): 213-21. https://doi.org/10.1002/em.21755
28. Bouraoui S., Mougou S., Brahem A., Tabka F., Ben Khelifa H., Harrabi I. et al. A combination of micronucleus assay and fluorescence in situ hybridization analysis to evaluate the genotoxicity of formaldehyde. Arch. Environ. Contam. Toxicol. 2013; 64(2): 337-44. https://doi.org/10.1007/s00244-012-9828-6
29. Costa S., Pina C., Coelho P., Costa C., Silva S., Porto B. et al. Occupational exposure to formaldehyde: genotoxic risk evaluation by comet assay and micronucleus test using human peripheral lymphocytes. J. Toxicol. Environ. Health A. 2011; 74(15-16): 1040-51. https://doi.org/10.1080/15287394.2011.582293
30. Ladeira C., Viegas S., Carolino E., Prista J., Gomes M.C., Brito M. Genotoxicity biomarkers in occupational exposure to formaldehyde – the case of histopathology laboratories. Mutat. Res. 2011; 721(1): 15-20. https://doi.org/10.1016/j.mrgentox.2010.11.015
31. Viegas S., Ladeira C., Nunes C., Malta-Vacas J., Gomes M., Brito M. et al. Genotoxic effects in occupational exposure to formaldehyde: A study in anatomy and pathology laboratories and formaldehyde-resins production. J. Occup. Med. Toxicol. 2010; 5(1): 25. https://doi.org/10.1186/1745-6673-5-25
32. Costa S., Coelho P., Costa C., Silva S., Mayan O., Santos L.S. et al. Genotoxic damage in pathology anatomy laboratory workers exposed to formaldehyde. Toxicology. 2008; 252(1-3): 40-8. https://doi.org/10.1016/j.tox.2008.07.056
33. Orsière T., Sari-Minodier I., Iarmarcovai G., Botta A. Genotoxic risk assessment of pathology and anatomy laboratory workers exposed to formaldehyde by use of personal air sampling and analysis of DNA damage in peripheral lymphocytes. Mutat. Res. 2006; 605(1-2): 30-41. https://doi.org/10.1016/j.mrgentox.2006.01.006
34. Costa S., Carvalho S., Costa C., Coelho P., Silva S., Santos L.S. et al. Increased levels of chromosomal aberrations and DNA damage in a group of workers exposed to formaldehyde. Mutagenesis. 2015; 30(4): 463-73. https://doi.org/10.1093/mutage/gev002
35. Formaldehyde: Method 3500 (Issue 2). In: NIOSH (National Institute for Occupational Safety and Health), ed. NIOSH Manual of Analytical Method U.S. Department of Health and Human Services. Cincinnati, Ohio; 1994: 2-5.
36. NIOSH Manual of Analytical Methods. 2541. Formaldehyde by GC. Available at: https://www.cdc.gov/niosh/docs/2003-154/pdfs/2541.pdf
37. American Conference of Governmental Industrial Hygienists. TLV’s and BEI’s – Based on the Documentation of the Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. ACGIH; 2017.
38. Bonassi S., El-Zein R., Bolognesi C., Fenech M. Micronuclei frequency in peripheral blood lymphocytes and cancer risk: evidence from human studies. Mutagenesis. 2011; 26(1): 93-100. https://doi.org/10.1093/mutage/geq075
39. Hopf N.B., Bolognesi C., Danuser B., Wild P. Biological monitoring of workers exposed to carcinogens using the buccal micronucleus approach: A systematic review and meta-analysis. Mutat. Res. 2019; 781: 11-29. https://doi.org/10.1016/j.mrrev.2019.02.006
40. Suruda A., Schulte P., Boeniger M., Hayes R.B., Livingston G.K., Steenland K. et al. Cytogenetic effects of formaldehyde exposure in students of mortuary science. Cancer Epidemiol. Biomarkers Prev. 1993; 2(5): 453-60.
41. Zeller J., Neuss S., Mueller J.U., Kühner S., Holzmann K., Högel J. et al. Assessment of genotoxic effects and changes in gene expression in humans exposed to formaldehyde by inhalation under controlled conditions. Mutagenesis. 2011; 26(4): 555-61. https://doi.org/10.1093/mutage/ger016
42. Bolognesi C., Knasmueller S., Nersesyan A., Thomas P., Fenech M. The HUMNxl scoring criteria for different cell types and nuclear anomalies in the buccal micronucleus cytome assay – an update and expanded photogallery. Mutat. Res. 2013; 753(2): 100-13. https://doi.org/10.1016/j.mrrev.2013.07.002
43. Fenech M., Holland N., Zeiger E., Chang W.P., Burgaz S., Thomas P. et al. The HUMN and HUMNxL international collaboration projects on human micronucleus assays in lymphocytes and buccal cells–past, present and future. Mutagenesis. 2011; 26(1): 239-45. https://doi.org/10.1093/mutage/geq051
44. He J.L., Jin L.F., Jin H.Y. Detection of cytogenetic effects in peripheral lymphocytes of students exposed to formaldehyde with cytokinesis-blocked micronucleus assay. Biomed. Environ. Sci. 1998; 11(1): 87-92.
45. Shaham J., Gurvich R., Kaufman Z. Sister chromatid exchange in pathology staff occupationally exposed to formaldehyde. Mutat. Res. 2002; 514(1-2): 115-23. https://doi.org/10.1016/s1383-5718(01)00334-5
46. Santovito A., Schilirò T., Castellano S., Cervella P., Bigatti M.P., Gilli G. et al. Combined analysis of chromosomal aberrations and glutathione S-transferase M1 and T1 polymorphisms in pathologists occupationally exposed to formaldehyde. Arch. Toxicol. 2011; 85(10): 1295-302. https://doi.org/10.1007/s00204-011-0668-3
47. Jakab M.G., Klupp T., Besenyei K., Biró A., Major J., Tompa A. Formaldehyde-induced chromosomal aberrations and apoptosis in peripheral blood lymphocytes of personnel working in pathology departments. Mutat. Res. 2010; 698(1-2): 11-7. https://doi.org/10.1016/j.mrgentox.2010.02.015
48. Musak L., Smerhovsky Z., Halasova E., Osina O., Letkova L., Vodickova L. et al. Chromosomal damage among medical staff occupationally exposed to volatile anesthetics, antineoplastic drugs, and formaldehyde. Scand. J. Work Environ. Health. 2013; 39(6): 618-30. https://doi.org/10.5271/sjweh.3358
49. Pala M., Ugolini D., Ceppi M., Rizzo F., Maiorana L., Bolognesi C. et al. Occupational exposure to formaldehyde and biological monitoring of Research Institute workers. Cancer Detect. Prev. 2008; 32(2): 121-6. https://doi.org/10.1016/j.cdp.2008.05.003
50. Thomson E.J., Shackleton S., Harrington J.M. Chromosome aberrations and sister-chromatid exchange frequencies in pathology staff occupationally exposed to formaldehyde. Mutat. Res. 1984; 141(2): 89-93. https://doi.org/10.1016/0165-7992(84)90016-2
51. Ogawa M., Kabe I., Terauchi Y., Tanaka S. A strategy for the reduction of formaldehyde concentration in a hospital pathology laboratory. J. Occup. Health. 2019; 61(1): 135-42. https://doi.org/10.1002/1348-9585.12018
52. Keshava N., Ong T.M. Occupational exposure to genotoxic agents. Mutat. Res. 1999; 437(2): 175-94. https://doi.org/10.1016/s1383-5742(99)00083-6
53. Ladeira C., Pádua M., Veiga L., Viegas S., Carolino E., Gomes M.C. et al. Influence of serum levels of vitamins A, D, and E as well as vitamin D receptor polymorphisms on micronucleus frequencies and other biomarkers of genotoxicity in workers exposed to formaldehyde. J. Nutrigenet. Nutrigenomics. 2015; 8(4-6): 205-14. https://doi.org/10.1159/000444486
54. Mierauskiene J., Lekevicius R., Lazutka J.R. Anticlastogenic effects of Aevitum intake in a group of chemical industry workers. Hereditas. 1993; 118(3): 201-4. https://doi.org/10.1111/j.1601-5223.1993.00201.x
55. Дурнев А.Д., Жанатаев А.К., Шредер О.В., Середенина В.С. Генотоксические поражения и болезни. Молекулярная медицина. 2013; (3): 3-19.
56. Дурнев А.Д. Антимутагенез и антимутагены. Физиология человека. 2018; 44(3): 116-37. https://doi.org/10.7868/S013116461803013X
Рецензия
Для цитирования:
Еремина Н.В., Жанатаев А.К., Дурнев А.Д. Генотоксические биомаркеры у сотрудников патологоанатомических лабораторий, работающих с формальдегидом (систематический обзор). Гигиена и санитария. 2020;99(8):792-802. https://doi.org/10.47470/0016-9900-2020-99-8-792-802
For citation:
Eremina N.V., Zhanataev A.K., Durnev A.D. Genotoxic biomarkers in employees of pathomorphological laboratories working with formaldehyde (systematic review). Hygiene and Sanitation. 2020;99(8):792-802. (In Russ.) https://doi.org/10.47470/0016-9900-2020-99-8-792-802
Просмотров: 410
Послать статью по эл. почте 