Prevalence of the metabolic syndrome and its components among Irkutsk region residents

Introduction. The metabolic syndrome (MS) is one of the manifestations of symptoms combination of endocrine and cardiovascular diseases. Its estimated incidence in 2005 was approximately 25% of the world population.

The aim of the study. To determine the prevalence of metabolic syndrome and its components among Irkutsk region residents.

Materials and methods. Seven hundred sixty nine men and 390 women aged 30 to 69 years were examined. Body mass index, glucose levels, and lipid metabolism parameters were calculated for all subjects. Relative abundance was compared using confidence intervals (CI).

Results. MS in the examined sample occurred in 45% (95% CI 42–49) of men and 61% (95% CI 57–66) of women (p<0.05). The prevalence of abdominal obesity among the cohort representatives was 57% (95% CI 54–61) and 79% (95% CI 75–83) in males and females, respectively. In women, the incidence of the cholesterol proatherogenic fraction was statistically significantly higher than in men: 82% (95% CI 76–86) and 70% (95% CI 65–75), respectively. The second most common was elevated triglyceride levels. Its frequency of occurrence was statistically significantly higher in men. The third place was occupied by a criterion associated with certain carbohydrate metabolism disorders. This criterion was statistically significantly more often recorded in females. Low concentration of the cholesterol antiatherogenic fraction as an additional criterion of MS ranked fourth in frequency of occurrence and did not statistically differ in men and women.

Limitations. Individuals living in the Irkutsk region. Subjects aged 30–69 years with no history of diabetes, stroke, or heart attack.

Conclusion. The prevalence of MS in the Irkutsk region is 45–61% for men and women, respectively, which is higher than the global average.

Compliance with ethical standards. The study was conducted in compliance with the ethical standards of the Helsinki Declaration (last revised). Conclusion of the local ethical committee of the East-Siberian Institute of Medical and Ecological Research No. 2 dated December 21, 2023. All participants gave informed voluntary written consent to participate in the study.

Contribution:
Kudaeva I.V. – the concept and design of the study, editing, statistical processing, writing text;
Kucherova N.G. – collection and processing of material, statistical processing;
Lysenko A.A. – collection and processing of material;
Rybakova A.P. – collection and processing of material.
All authors are responsible for the integrity of all parts of the manuscript and approval of the manuscript final version.

Conflict of interests. The authors declare no conflict of interests.

Funding. The study had no funding and was performed within the framework of the funds allocated for exploratory scientific research of East-Siberian Institute of Medical and Ecological Research.

Received: October 3, 2025 / Revise d: November 1, 2025 / Accepted: November 3, 2025 / Published: December 19, 2025

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