Pulmonary gas exchange and acid-base status of blood under the use of means for individual protection of respiratory organs

The aim of the study was to evaluate the effect of the duration of training on the use of personal respiratory protective equipment on indices of pulmonary gas exchange. Simulation of conditions for the use of personal respiratory protective equipment was carried out at the inspiratory resistance of 40, 60, 70 and 80% Pmmax. The study included 38 healthy male subjects aged 20 to 36 years. According to the results of the study, under the use of personal protective equipment for the respiratory system, preliminary training was shown to be essential. In the subjects without preliminary training, the use of personal protective equipment was followed by a weak change in the nature of the respiratory pattern. After the preliminary training subjects had an adaptive rearrangement of the respiratory pattern, consisted of the decline in breathing movements as the respiratory resistance increased. Preliminary training to the exposure of additional resistance to breathing, altered pulmonary gas exchange and acid-base state of blood. The trained subjects had higher pCO2 blood values and lower values of pO2. They showed a greater deficit of buffer bases of plasma compared to untrained ones. This fact testified the preliminary training for the use of personal respiratory protective equipment (long-term adaptation) changed the gas composition and acid-base state of the blood to be a more economical mode of the discharge of buffer systems. On the basis of the data obtained, the preliminary training for increased respiratory resistance was suggested to be advisable before the using personal respiratory protective equipment.

1. Kaminsky S.L. Basics of rational respiratory protection in the workplace. M.: Pro-spectrum of Science; 2007: 208.

2. Russell J. The gas mask. M .: The book on Demand, 2012:104.

3. Technical and special means of ensuring civil defense and protection from emergency situations. St. Petersburg: Institute for Risk and Safety; 2007: 232.

4. Byalovsky Yu.Y. Reciprocal reactions of the body to different values of increased resistance to breathing. Russian medical and biological bulletin named after academician I.P. Pavlova. 2016; 1: 19-25.

5. Byalovsky Yu.Yu., Bulatetsky S.V. The reaction of the body’s systems to increased resistance to breathing in groups with different levels of adaptive capacity. Central Scientific Bulletin. 2016; 1 (4): 7-11.

6. Byalovsky Yu.Y. The system organization of adaptive human activity in conditions of additional respiratory resistance. Dis .... kand. for the competition uch. Art. D.M. Ryazan; 1996: 277.

7. Alexandrova N.P. The relative contribution of the muscles of the chest and diaphragm to the work of respiration with an inspiratory resistive load. Fiziol. Journal. 1993; 79 (11): 64-71.

8. Pneumatic doser of external resistance to breathing. Yu.Yu. Byalovsky, V.N. Abrosimov. Description of the invention to the Russian Federation patent No. 2071790, 01.20.1997.

9. Leupold W., Roth J. Moglichkeiten des Einzatzes der Kapnographie im Rahmen von inhalativen Provokationstesten. Pneumologie. 1984; 38 (7): 256-60.

10. Severinghaus J.W., Stupfel M.A., Bradley A.F. Alveolar dead space in the dog and man. J. Appl. Physiol. 1957; 10: 349.

11. Van Meerten R.J. Expiratory gas concentration curves for examination of uneven distribution of ventilation and perfusion in the lung. Second Communication: experiments. Respiration. 1971; 28: 167.

12. Cherniack N.S. Load Detection and Breathlessness. Breathlessness. The Campbell Symposium. Canada; 1992: 66-71.

13. Gibson J., Gilmartin J.J., Vealle D., Walls T.J. et all. Respiratory Muscle Function in Neuromuscular Disease. Breathlessness. The Campbell Symposium. Canada: 1992: 66-71.

14. Byalovsky Yu.Yu., Bulatetsky S.V., Glushkova E.P. The system organization of nonspecific mechanisms of adaptation in restorative medicine: monograph. Yu. Yu. Byalovsky. Voronezh: OOO RITM Publishing House; 2017: 406.

15. Aleksandrova N.P., Isaev G.G. Central and peripheral components of diaphragmatic fatigue during an inspiratory resistive load in cats. Acta Physiol. Scand. 1997; 161: 355.